KEGG   Homo sapiens (human): 126969Help
Entry
126969            CDS       T01001                                 

Gene name
SLC44A3, CTL3
Definition
(RefSeq) solute carrier family 44 member 3
  KO
K15282  solute carrier family 44 (choline transporter-like protein), member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    126969 (SLC44A3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    126969 (SLC44A3)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC44: Choline-like transporter
   126969 (SLC44A3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Choline_transpo
Motif
Other DBs
NCBI-GeneID: 126969
NCBI-ProteinID: NP_001107578
HGNC: 28689
Ensembl: ENSG00000143036
Vega: OTTHUMG00000010700
Pharos: Q8N4M1(Tdark)
UniProt: Q8N4M1
Position
1p21.3
AA seq 653 aa AA seqDB search
MHCLGAEYLVSAEGAPRQREWRPQIYRKCTDTAWLFLFFLFWTGLVFIMGYSVVAGAAGR
LLFGYDSFGNMCGKKNSPVEGAPLSGQDMTLKKHVFFMNSCNLEVKGTQLNRMALCVSNC
PEEQLDSLEEVQFFANTSGSFLCVYSLNSFNYTHSPKADSLCPRLPVPPSKSFPLFNRCV
PQTPECYSLFASVLINDVDTLHRILSGIMSGRDTILGLCILALALSLAMMFTFRFITTLL
VHIFISLVILGLLFVCGVLWWLYYDYTNDLSIELDTERENMKCVLGFAIVSTGITAVLLV
LIFVLRKRIKLTVELFQITNKAISSAPFLLFQPLWTFAILIFFWVLWVAVLLSLGTAGAA
QVMEGGQVEYKPLSGIRYMWSYHLIGLIWTSEFILACQQMTIAGAVVTCYFNRSKNDPPD
HPILSSLSILFFYHQGTVVKGSFLISVVRIPRIIVMYMQNALKEQQHGALSRYLFRCCYC
CFWCLDKYLLHLNQNAYTTTAINGTDFCTSAKDAFKILSKNSSHFTSINCFGDFIIFLGK
VLVVCFTVFGGLMAFNYNRAFQVWAVPLLLVAFFAYLVAHSFLSVFETVLDALFLCFAVD
LETNDGSSEKPYFMDQEFLSFVKRSNKLNNARAQQDKHSLRNEEGTELQAIVR
NT seq 1962 nt NT seq  +upstreamnt  +downstreamnt
atgcactgcctgggcgccgagtacctggtttctgcagaaggagcccctaggcaaagggag
tggcgaccccagatttataggaaatgcacagatacggcatggttattcctgttctttctc
ttttggactggtttggtgtttatcatgggctactcggtggtggctggagccgcgggaaga
ctcctctttggctatgacagctttggcaacatgtgtggcaagaagaactcccccgtggaa
ggggcccctctttcagggcaggacatgaccctaaaaaaacacgtgttctttatgaattcc
tgcaacctggaagtcaaaggtacgcagctcaaccgcatggccctctgtgtatccaactgc
cctgaagagcagcttgactccctggaagaggtccagttctttgcaaacaccagtgggtcc
ttcctgtgtgtttatagtttgaattccttcaactatacccacagtccaaaagcagactca
ctgtgtcccaggctaccagttcctccaagcaagtcatttcccttatttaaccgatgtgtc
cctcaaacacctgagtgctactccctatttgcatctgttttgataaatgatgttgacacc
ctccaccgaattctaagtggaatcatgtcgggaagagatacaatccttggcctgtgtatc
ctcgcattagccttgtctttggccatgatgtttaccttcagattcatcaccacccttctg
gttcacattttcatttcattggttattttgggattgttgtttgtctgcggtgttttatgg
tggctgtattatgactataccaacgacctcagcatagaattggacacagaaagggaaaat
atgaagtgcgtgctggggtttgctatcgtatccacaggcatcacggcagtgctgctcgtc
ttgatttttgttctcagaaagagaataaaattgacagttgagcttttccaaatcacaaat
aaagccatcagcagtgctcccttcctgctgttccagccactgtggacatttgccatcctc
attttcttctgggtcctctgggtggctgtgctgctgagcctgggaactgcaggagctgcc
caggttatggaaggcggccaagtggaatataagcccctttcgggcattcggtacatgtgg
tcgtaccatttaattggcctcatctggactagtgaattcatccttgcgtgccagcaaatg
actatagctggggcagtggttacttgttatttcaacagaagtaaaaatgatcctcctgat
catcccatcctttcgtctctctccattctcttcttctaccatcaaggaaccgttgtgaaa
gggtcatttttaatctctgtggtgaggattccgagaatcattgtcatgtacatgcaaaac
gcactgaaagaacagcagcatggtgcattgtccaggtacctgttccgatgctgctactgc
tgtttctggtgtcttgacaaatacctgctccatctcaaccagaatgcatatactacaact
gctattaatgggacagatttctgtacatcagcaaaagatgcattcaaaatcttgtccaag
aactcaagtcactttacatctattaactgctttggagacttcataatttttctaggaaag
gtgttagtggtgtgtttcactgtttttggaggactcatggcttttaactacaatcgggca
ttccaggtgtgggcagtccctctgttattggtagctttttttgcctacttagtagcccat
agttttttatctgtgtttgaaactgtgctggatgcacttttcctgtgttttgctgttgat
ctggaaacaaatgatggatcgtcagaaaagccctactttatggatcaagaatttctgagt
ttcgtaaaaaggagcaacaaattaaacaatgcaagggcacagcaggacaagcactcatta
aggaatgaggagggaacagaactccaggccattgtgagatag

KEGG   Homo sapiens (human): 204962Help
Entry
204962            CDS       T01001                                 

Gene name
SLC44A5, CTL5
Definition
(RefSeq) solute carrier family 44 member 5
  KO
K15377  solute carrier family 44 (choline transporter-like protein), member 2/4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    204962 (SLC44A5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    204962 (SLC44A5)
   04147 Exosome [BR:hsa04147]
    204962 (SLC44A5)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC44: Choline-like transporter
   204962 (SLC44A5)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   204962 (SLC44A5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Choline_transpo
Motif
Other DBs
NCBI-GeneID: 204962
NCBI-ProteinID: NP_689910
HGNC: 28524
Ensembl: ENSG00000137968
Vega: OTTHUMG00000009721
Pharos: Q8NCS7(Tdark)
UniProt: Q8NCS7
Position
1p31.1
AA seq 719 aa AA seqDB search
MNDTEKPADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCMIFLLCIIGYIVLGLVAW
VHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLRCTSPSVLLNLQCPTTQICVSK
CPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTTAKPVKSLTQLLLDDDCPTAIFPSKPFLQ
RCFPDFSTKNGTLTIGSKMMFQDGNGGTRSVVELGIAANGINKLLDAKSLGLKVFEDYAR
TWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMIGVIGIIGYGIWHCYQQYTNLQERP
SSVLTIYDIGIQTNISMYFELQQTWFTFMIILCIIEVIVILMLIFLRNRIRVAIILLKEG
SKAIGYVPSTLVYPALTFILLSICICYWVVTAVFLATSGVPVYKVIAPGGHCIHENQTCD
PEIFNTTEIAKACPGALCNFAFYGGKSLYHQYIPTFHVYNLFVFLWLINFVIALGQCALA
GAFATYYWAMKKPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRL
KRTQNTLSKFLQCCLRCCFWCLENAIKFLNRNAYIMIAIYGRNFCRSAKDAFNLLMRNVL
KVAVTDEVTYFVLFLGKLLVAGSIGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVIFGS
YLIAHGFFSVYAMCVETIFICFCEDLERNDGSTEKPYFVTPNLHGILIKKQLVPQKQKE
NT seq 2160 nt NT seq  +upstreamnt  +downstreamnt
atgaatgacacagaaaaaccagcagatactccctctgaggaagaggactttggtgatcca
aggacatatgacccagatttcaaggggcctgttgccaacaggagttgtacagatgttctg
tgctgtatgatcttcctactgtgtattattggctacattgttttaggacttgtggcctgg
gtacatggggaccccagaagagcagcctatcctacagacagccagggccacttttgtggc
cagaagggcactcccaatgagaacaagaccattttgttttactttaacctgttacgctgt
accagtccctccgtgttgctaaacctacagtgccctaccacacagatctgtgtctccaag
tgcccagaaaaatttttaacctatgtggaaatgcaacttttgtacacaaaagacaaaagc
tactgggaagactaccgtcagttctgtaagaccactgctaagcctgtgaagtctctcaca
cagcttttactggatgatgattgtccaacagcgatttttcccagcaaaccttttctccag
agatgtttccctgacttctctaccaaaaatggcactttaacaataggaagtaagatgatg
tttcaagatggaaatggagggacaagaagtgttgtagaactcgggattgctgcaaatggt
atcaataaacttcttgatgcaaagtcacttggattgaaagtgtttgaagactatgcaaga
acttggtattggattctcattggcctgacgattgccatggtccttagttggatatttttg
atacttctgaggttcatagctggatgcctcttctgggtcttcatgattggtgtgattgga
attataggttatggaatatggcactgttaccagcagtacaccaatcttcaggaacgccca
agttctgtattaactatctatgacatcgggattcagactaacataagcatgtactttgaa
ctgcaacaaacatggttcacatttatgataatactctgcatcattgaagtgattgtcatc
ctcatgctgatcttcctcaggaatcgaatccgagtcgccattatcctgctgaaggaagga
agcaaagccattggatatgttcctagtacattagtctatccagctttaactttcattttg
ctctcaatctgcatttgctactgggtcgtgacagcagttttcttggcgacatcgggggta
cctgtatacaaagtcatagctccaggggggcattgtatacatgaaaatcaaacctgtgac
ccagagatttttaatacaactgaaattgccaaagcttgccctggggctctgtgtaacttt
gctttctatggtggaaagagcttgtaccatcagtacatccctaccttccatgtatacaac
ttatttgtctttctctggcttataaacttcgtcattgcattaggtcagtgcgcccttgct
ggtgcattcgctacttattactgggccatgaaaaaacctgatgacatcccacgatatcca
ctttttactgcatttggacgagccatacgatatcacacaggatccctagcatttggatct
ttaattattgcattaattcaaatgtttaaaattgtactagaatacttggaccaccgtctt
aaacgtacccagaacacattgtctaaattcctacaatgctgcctgagatgctgcttctgg
tgtttggaaaatgcaataaagtttttaaacagaaatgcctatattatgattgcaatatat
ggcagaaacttctgcaggtcagcaaaagatgctttcaatctgctgatgagaaatgttttg
aaagttgcagttacagatgaagttacatactttgtattattcctggggaaacttctagtt
gctggaagtataggtgttctggccttcctattcttcacacaaagactgccagtgattgca
caaggaccagcatctttaaattactactgggtacctttgctgacagtcatttttgggtct
tacctgattgcacatgggttcttcagcgtctatgcaatgtgtgttgaaacaattttcatc
tgcttctgtgaagatctggaaagaaatgatggatctacagaaaaaccctacttcgtaacc
cctaacctgcatggaattctgatcaagaagcaactagttccccagaagcagaaagagtag

KEGG   Homo sapiens (human): 23446Help
Entry
23446             CDS       T01001                                 

Gene name
SLC44A1, CD92, CDW92, CHTL1, CTL1
Definition
(RefSeq) solute carrier family 44 member 1
  KO
K06515  solute carrier family 44 (choline transporter-like protein), member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    23446 (SLC44A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    23446 (SLC44A1)
   04090 CD molecules [BR:hsa04090]
    23446 (SLC44A1)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC44: Choline-like transporter
   23446 (SLC44A1)
CD molecules [BR:hsa04090]
 Proteins
  23446 (SLC44A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Choline_transpo
Motif
Other DBs
NCBI-GeneID: 23446
NCBI-ProteinID: NP_536856
OMIM: 606105
HGNC: 18798
Ensembl: ENSG00000070214
Vega: OTTHUMG00000020421
Pharos: Q8WWI5(Tbio)
UniProt: Q8WWI5 A0A024R151
Position
9q31.1-q31.2
AA seq 657 aa AA seqDB search
MGCCSSASSAAQSSKREWKPLEDRSCTDIPWLLLFILFCIGMGFICGFSIATGAAARLVS
GYDSYGNICGQKNTKLEAIPNSGMDHTQRKYVFFLDPCNLDLINRKIKSVALCVAACPRQ
ELKTLSDVQKFAEINGSALCSYNLKPSEYTTSPKSSVLCPKLPVPASAPIPFFHRCAPVN
ISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVL
VWILTILVILGSLGGTGVLWWLYAKQRRSPKETVTPEQLQIAEDNLRALLIYAISATVFT
VILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWVYWIMTLLFLG
TTGSPVQNEQGFVEFKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDK
RNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGKENACARCVLK
SCICCLWCLEKCLNYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVATINTVGDFML
FLGKVLIVCSTGLAGIMLLNYQQDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLC
FAIDTKYNDGSPGREFYMDKVLMEFVENSRKAMKEAGKGGVADSRELKPMASGASSA
NT seq 1974 nt NT seq  +upstreamnt  +downstreamnt
atgggctgctgcagctccgcctcctccgccgcgcagagctccaaacgagaatggaagccg
ctggaggaccgtagctgcacagacataccatggctgctgctcttcatcctcttctgcatt
gggatgggatttatttgtggcttttcaatagcaacaggtgcagcagcaagactagtgtca
ggatacgacagctatggaaatatctgtgggcagaaaaatacaaagttggaagcaatacca
aacagtggcatggaccacacccagcggaagtatgtattctttttggatccatgcaacctg
gacttgataaaccggaagattaagtctgtagcactgtgtgtagcagcgtgtccaaggcaa
gaactgaaaactctgagtgatgttcagaagtttgcagagataaatggttcagccctatgt
agctacaacctaaagccttctgaatacactacatctccaaaatcttctgttctctgcccc
aaactaccagttccagcgagtgcacctattccattcttccatcgctgtgctcctgtgaac
atttcctgctatgccaagtttgcagaggccctgatcacctttgtcagtgacaatagtgtc
ttacacaggctgattagtggagtaatgaccagcaaagaaattatattgggactttgcttg
ttatcactagttctatccatgattttgatggtgataatcaggtatatatcaagagtactt
gtgtggatcttaacgattctggtcatactcggttcacttggaggcacaggtgtactatgg
tggctgtatgcaaagcaaagaaggtctcccaaagaaactgttactcctgagcagcttcag
atagctgaagacaatcttcgggccctcctcatttatgccatttcagctacagtgttcaca
gtgatcttattcctgataatgttggttatgcgcaaacgtgttgctcttaccatcgccttg
ttccacgtagctggcaaggtcttcattcacttgccactgctagtcttccaacccttctgg
actttctttgctcttgtcttgttttgggtgtactggatcatgacacttctttttcttggc
actaccggcagtcctgttcagaatgagcaaggctttgtggagttcaaaatttctgggcct
ctgcagtacatgtggtggtaccatgtggtgggcctgatttggatcagtgaatttattcta
gcatgtcagcagatgacagtggcaggagctgtggtaacatactattttactagggataaa
aggaatttgccatttacacctattttggcatcagtaaatcgccttattcgttaccaccta
ggtacggtggcaaaaggatctttcattatcacattagtcaaaattccgcgaatgatcctt
atgtatattcacagtcagctcaaaggaaaggaaaatgcttgtgcacgatgtgtgctgaaa
tcttgcatttgttgcctttggtgtcttgaaaagtgcctaaattatttaaatcagaatgca
tacacagccacagctatcaacagcaccaacttctgcacctcagcaaaggatgcctttgtc
attctggtggagaatgctttgcgagtggctaccatcaacacagtaggagattttatgtta
ttccttggcaaggtgctgatagtctgcagcacaggtttagctgggattatgctgctcaac
taccagcaggactacacagtatgggtgctgcctctgatcatcgtctgcctctttgctttc
ctagtcgctcattgcttcctgtctatttatgaaatggtagtggatgtattattcttgtgt
tttgccattgatacaaaatacaatgatgggagccctggcagagaattctatatggataaa
gtgctgatggagtttgtggaaaacagtaggaaagcaatgaaagaagctggtaagggaggc
gtcgctgattccagagagctaaagccgatggcttcgggagcaagttctgcttga

KEGG   Homo sapiens (human): 57153Help
Entry
57153             CDS       T01001                                 

Gene name
SLC44A2, CTL2, PP1292
Definition
(RefSeq) solute carrier family 44 member 2
  KO
K15377  solute carrier family 44 (choline transporter-like protein), member 2/4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    57153 (SLC44A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    57153 (SLC44A2)
   04147 Exosome [BR:hsa04147]
    57153 (SLC44A2)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC44: Choline-like transporter
   57153 (SLC44A2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   57153 (SLC44A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Choline_transpo
Motif
Other DBs
NCBI-GeneID: 57153
NCBI-ProteinID: NP_065161
OMIM: 606106
HGNC: 17292
Ensembl: ENSG00000129353
Vega: OTTHUMG00000180585
Pharos: Q8IWA5(Tbio)
UniProt: Q8IWA5
Position
19p13.2
AA seq 706 aa AA seqDB search
MGDERPHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVFLLLAIVGYVAVGIIAWTHGDP
RKVIYPTDSRGEFCGQKGTKNENKPYLFYFNIVKCASPLVLLEFQCPTPQICVEKCPDRY
LTYLNARSSRDFEYYKQFCVPGFKNNKGVAEVLQDGDCPAVLIPSKPLARRCFPAIHAYK
GVLMVGNETTYEDGHGSRKNITDLVEGAKKANGVLEARQLAMRIFEDYTVSWYWIIIGLV
IAMAMSLLFIILLRFLAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLG
FQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCS
LLYPLVTFFLLCLCIAYWASTAVFLSTSNEAVYKIFDDSPCPFTAKTCNPETFPSSNESR
QCPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALR
KPDDLPAFPLFSAFGRALRYHTGSLAFGALILAIVQIIRVILEYLDQRLKAAENKFAKCL
MTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDF
LFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIVGSYLIAHGFFSVY
GMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLNKTNKKAAES
NT seq 2121 nt NT seq  +upstreamnt  +downstreamnt
atgggggacgagcggccccactactacgggaaacacggaacgccacagaagtatgatccc
actttcaaaggacccatttacaataggggctgcacggatatcatatgctgtgtgttcctg
ctcctggccattgtgggctacgtggctgtaggcatcatagcctggactcatggagaccct
cgaaaggtgatctaccccactgacagccggggcgagttctgcgggcagaagggcacaaaa
aacgagaacaaaccctatctgttttatttcaacattgtgaaatgtgccagccccctggtt
ctgctggaattccaatgtcccactccccagatctgcgtggaaaaatgccccgaccgctac
ctcacgtacctgaatgctcgcagctcccgggactttgagtactataagcagttctgtgtt
cctggcttcaagaacaataaaggagtggctgaggtgcttcaagatggtgactgccctgct
gtcctcatccccagcaaacccttggcccggagatgcttccccgctatccacgcctacaag
ggtgtcctgatggtgggcaatgagacgacctatgaggatgggcatggctcccggaaaaac
atcacagacctggtggagggcgccaagaaagccaatggagtcctagaggcgcggcaactc
gccatgcgcatatttgaagattacaccgtctcttggtactggattatcataggcctggtc
attgccatggcgatgagcctcctgttcatcatcctgcttcgcttcctggctggtattatg
gtctgggtgatgatcatcatggtgattctggtgctgggctacggaatatttcactgctac
atggagtactcccgactgcgtggtgaggccggctctgatgtctctttggtggacctcggc
tttcagacggatttccgggtgtacctgcacttacggcagacctggttggcctttatgatc
attctgagtatccttgaagtcattatcatcttgctgctcatctttctccggaagagaatt
ctcatcgcgattgcactcatcaaagaagccagcagggctgtgggatacgtcatgtgctcc
ttgctctacccactggtcaccttcttcttgctgtgcctctgcatcgcctactgggccagc
actgctgtcttcctgtccacttccaacgaagcggtctataagatctttgatgacagcccc
tgcccatttactgcgaaaacctgcaacccagagaccttcccctcctccaatgagtcccgc
caatgccccaatgcccgttgccagttcgccttctacggtggtgagtcgggctaccaccgg
gccctgctgggcctgcagatcttcaatgccttcatgttcttctggttggccaacttcgtg
ctggcgctgggccaggtcacgctggccggggcctttgcctcctactactgggccctgcgc
aagccggacgacctgccggccttcccgctcttctctgcctttggccgggcgctcaggtac
cacacaggctccctggcctttggcgcgctcatcctggccattgtgcagatcatccgtgtg
atactcgagtacctggatcagcggctgaaagctgcagagaacaagtttgccaagtgcctc
atgacctgtctcaaatgctgcttctggtgcctggagaagttcatcaaattccttaatagg
aatgcctacatcatgattgccatctacggcaccaatttctgcacctcggccaggaatgcc
ttcttcctgctcatgagaaacatcatcagagtggctgtcctggataaagttactgacttc
ctcttcctgttgggcaaacttctgatcgttggtagtgtggggatcctggctttcttcttc
ttcacccaccgtatcaggatcgtgcaggatacagcaccacccctcaattattactgggtt
cctatactgacggtgatcgttggctcctacttgattgcacacggtttcttcagcgtctat
ggcatgtgtgtggacacgctgttcctctgcttcttggaggacctggagaggaatgacggc
tcggccgagaggccttacttcatgtcttccaccctcaagaaactcttgaacaagaccaac
aagaaggcagcggagtcctga

KEGG   Homo sapiens (human): 60482Help
Entry
60482             CDS       T01001                                 

Gene name
SLC5A7, CHT, CHT1, CMS20, HMN7A
Definition
(RefSeq) solute carrier family 5 member 7
  KO
K14387  solute carrier family 5 (high affinity choline transporter), member 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04725  Cholinergic synapse
hsa05231  Choline metabolism in cancer
Disease
H00770  Congenital myasthenic syndrome
H00856  Distal hereditary motor neuropathies
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    60482 (SLC5A7)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    60482 (SLC5A7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    60482 (SLC5A7)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC5: Sodium glucose cotransporter
   60482 (SLC5A7)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SSF
Motif
Other DBs
NCBI-GeneID: 60482
NCBI-ProteinID: NP_001291934
OMIM: 608761
HGNC: 14025
Ensembl: ENSG00000115665
Vega: OTTHUMG00000130959
Pharos: Q9GZV3(Tchem)
UniProt: Q9GZV3 B2RCU2
Position
2q12.3
AA seq 580 aa AA seqDB search
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTA
TWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQ
IYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGG
LYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDW
NQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFA
RNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQ
LLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLD
ELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
NT seq 1743 nt NT seq  +upstreamnt  +downstreamnt
atggctttccatgtggaaggactgatagctatcatcgtgttctaccttctaattttgctg
gttggaatatgggctgcctggagaaccaaaaacagtggcagcgcagaagagcgcagcgaa
gccatcatagttggtggccgagatattggtttattggttggtggatttaccatgacagct
acctgggtcggaggagggtatatcaatggcacagctgaagcagtttatgtaccaggttat
ggcctagcttgggctcaggcaccaattggatattctcttagtctgattttaggtggcctg
ttctttgcaaaacctatgcgttcaaaggggtatgtgaccatgttagacccgtttcagcaa
atctatggaaaacgcatgggcggactcctgtttattcctgcactgatgggagaaatgttc
tgggctgcagcaattttctctgctttgggagccaccatcagcgtgatcatcgatgtggat
atgcacatttctgtcatcatctctgcactcattgccactctgtacacactggtgggaggg
ctctattctgtggcctacactgatgtcgttcagctcttttgcatttttgtagggctgtgg
atcagcgtcccctttgcattgtcacatcctgcagtcgcagacatcgggttcactgctgtg
catgccaaataccaaaagccgtggctgggaactgttgactcatctgaagtctactcttgg
cttgatagttttctgttgttgatgctgggtggaatcccatggcaagcatactttcagagg
gttctctcttcttcctcagccacctatgctcaagtgctgtccttcctggcagctttcggg
tgcctggtgatggccatcccagccatactcattggggccattggagcatcaacagactgg
aaccagactgcatatgggcttccagatcccaagactacagaagaggcagacatgatttta
ccaattgttctgcagtatctctgccctgtgtatatttctttctttggtcttggtgcagtt
tctgctgctgttatgtcatcagcagattcttccatcttgtcagcaagttccatgtttgca
cggaacatctaccagctttccttcagacaaaatgcttcggacaaagaaatcgtttgggtt
atgcgaatcacagtgtttgtgtttggagcatctgcaacagccatggccttgctgacgaaa
actgtgtatgggctctggtacctcagttctgaccttgtttacatcgttatcttcccccag
ctgctttgtgtactctttgttaagggaaccaacacctatggggccgtggcaggttatgtt
tctggcctcttcctgagaataactggaggggagccatatctgtatcttcagcccttgatc
ttctaccctggctattaccctgatgataatggtatatataatcagaaatttccatttaaa
acacttgccatggttacatcattcttaaccaacatttgcatctcctatctagccaagtat
ctatttgaaagtggaaccttgccacctaaattagatgtatttgatgctgttgttgcaaga
cacagtgaagaaaacatggataagacaattcttgtcaaaaatgaaaatattaaattagat
gaacttgcacttgtgaagccacgacagagcatgaccctcagctcaactttcaccaataaa
gaggccttccttgatgttgattccagtccagaagggtctgggactgaagataatttacag
tga

KEGG   Homo sapiens (human): 6580Help
Entry
6580              CDS       T01001                                 

Gene name
SLC22A1, HOCT1, OCT1, oct1_cds
Definition
(RefSeq) solute carrier family 22 member 1
  KO
K08198  MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04976  Bile secretion
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    6580 (SLC22A1)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    6580 (SLC22A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6580 (SLC22A1)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   6580 (SLC22A1)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family [TC:2.A.1.19]
    6580 (SLC22A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Sugar_tr MFS_1
Motif
Other DBs
NCBI-GeneID: 6580
NCBI-ProteinID: NP_003048
OMIM: 602607
HGNC: 10963
Ensembl: ENSG00000175003
Vega: OTTHUMG00000015947
Pharos: O15245(Tchem)
UniProt: O15245
Position
6q25.3
AA seq 554 aa AA seqDB search
MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
NT seq 1665 nt NT seq  +upstreamnt  +downstreamnt
atgcccaccgtggatgacattctggagcaggttggggagtctggctggttccagaagcaa
gccttcctcatcttatgcctgctgtcggctgcctttgcgcccatctgtgtgggcatcgtc
ttcctgggtttcacacctgaccaccactgccagagtcctggggtggctgagctgagccag
cgctgtggctggagccctgcggaggagctgaactatacagtgccaggcctggggcccgcg
ggcgaggccttccttggccagtgcaggcgctatgaagtggactggaaccagagcgccctc
agctgtgtagaccccctggctagcctggccaccaacaggagccacctgccgctgggtccc
tgccaggatggctgggtgtatgacacgcccggctcttccatcgtcactgagttcaacctg
gtgtgtgctgactcctggaagctggacctctttcagtcctgtttgaatgcgggcttcttg
tttggctctctcggtgttggctactttgcagacaggtttggccgtaagctgtgtctcctg
ggaactgtgctggtcaacgcggtgtcgggcgtgctcatggccttctcgcccaactacatg
tccatgctgctcttccgcctgctgcagggcctggtcagcaagggcaactggatggctggc
tacaccctaatcacagaatttgttggctcgggctccagaagaacggtggcgatcatgtac
cagatggccttcacggtggggctggtggcgcttaccgggctggcctacgccctgcctcac
tggcgctggctgcagctggcagtctccctgcccaccttcctcttcctgctctactactgg
tgtgtgccggagtcccctcggtggctgttatcacaaaaaagaaacactgaagcaataaag
ataatggaccacatcgctcaaaagaatgggaagttgcctcctgctgatttaaagatgctt
tccctcgaagaggatgtcaccgaaaagctgagcccttcatttgcagacctgttccgcacg
ccgcgcctgaggaagcgcaccttcatcctgatgtacctgtggttcacggactctgtgctc
tatcaggggctcatcctgcacatgggcgccaccagcgggaacctctacctggatttcctt
tactccgctctggtcgaaatcccgggggccttcatagccctcatcaccattgaccgcgtg
ggccgcatctaccccatggccatgtcaaatttgttggcgggggcagcctgcctcgtcatg
atttttatctcacctgacctgcactggttaaacatcataatcatgtgtgttggccgaatg
ggaatcaccattgcaatacaaatgatctgcctggtgaatgctgagctgtaccccacattc
gtcaggaacctcggagtgatggtgtgttcctccctgtgtgacataggtgggataatcacc
cccttcatagtcttcaggctgagggaggtctggcaagccttgcccctcattttgtttgcg
gtgttgggcctgcttgccgcgggagtgacgctacttcttccagagaccaagggggtcgct
ttgccagagaccatgaaggacgccgagaaccttgggagaaaagcaaagcccaaagaaaac
acgatttaccttaaggtccaaacctcagaaccctcgggcacctga

KEGG   Homo sapiens (human): 6581Help
Entry
6581              CDS       T01001                                 

Gene name
SLC22A3, EMT, EMTH, OCT3
Definition
(RefSeq) solute carrier family 22 member 3
  KO
K08200  MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    6581 (SLC22A3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6581 (SLC22A3)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   6581 (SLC22A3)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family [TC:2.A.1.19]
    6581 (SLC22A3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Sugar_tr MFS_1
Motif
Other DBs
NCBI-GeneID: 6581
NCBI-ProteinID: NP_068812
OMIM: 604842
HGNC: 10967
Ensembl: ENSG00000146477
Vega: OTTHUMG00000015953
Pharos: O75751(Tchem)
UniProt: O75751
Position
6q25.3
AA seq 556 aa AA seqDB search
MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALA
ERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNR
SAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYG
RIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRR
IVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKK
GDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFT
SAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVA
CLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFG
GIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSPHS
CKCGRNKKTPVSRSHL
NT seq 1671 nt NT seq  +upstreamnt  +downstreamnt
atgccctccttcgacgaggcgctgcagcgggtgggcgagttcgggcgcttccagaggcgc
gtgtttttgctgctgtgcctgacgggcgtcaccttcgccttcctcttcgtcggcgtggtc
ttcctgggcacgcagcccgaccactactggtgccgcgggccaagtgccgcggcgctggcc
gagcgctgcggctggagcccggaggaggagtggaaccgcacggcgcccgcctcccgcggc
ccagagccccccgagcgccgcggccgctgccagcgctacctcctggaggcggccaacgac
agcgcctccgccactagcgctctcagctgcgcggacccactcgccgccttccccaaccgc
tcggctccccttgtgccgtgccgcggcggctggcgctacgcccaggcccactccaccatc
gtcagcgagtttgaccttgtctgtgtcaatgcgtggatgctggacctcacccaagccatc
ctgaacctcggcttcctgactggagcattcaccttaggctatgcagcagacaggtatggc
aggatcgtcatttacttgctatcctgccttggtgttggcgtcactggggttgtggtggcc
tttgcaccaaacttccctgtgtttgtgatcttccgcttcctgcaaggtgtatttggaaag
gggacgtggatgacttgctacgtgattgtgacagaaatagtaggttcgaaacaaaggagg
attgtgggaatcgtgattcaaatgttctttacccttggaatcataattctccctggaatt
gcctacttcatccccaactggcaaggaatccagttagccatcacgctgcccagctttctc
ttcctcctttattactgggtggtccctgagtctccccgttggctgattactcggaagaaa
ggagataaagcattacagatcctgagacgcattgctaagtgcaatgggaaatacctctca
tcaaattactcagagatcactgttacagatgaggaagttagtaatccatcctttttagat
ctggtgagaactccccaaatgaggaaatgcacacttattcttatgtttgcttggttcaca
agcgcagtggtgtatcaaggacttgtcatgcgcctgggaattatagggggcaacctctat
atagactttttcatctcgggcgtggtggaactgccaggagctctcttgatcttactaacc
attgagcgccttggacgacgcctcccctttgcggcaagcaatatagtggcaggggtggca
tgccttgtcactgcgttcttaccagaaggaatagcatggttgaggaccacagtggctaca
ttgggaagactagggataaccatggcctttgaaattgtttatttggtaaattcagaattg
tacccaacaacattacgaaatttcggagtttcgctctgttcaggtctgtgtgattttggg
ggaatcatagccccatttctgctctttcggctagcagccgtgtggctagaactacctctg
atcatctttggtatcctggcatccatctgtggtggccttgtgatgcttttgcctgaaacc
aagggtattgccttgccagagacagtggatgatgtagaaaaacttggcagtccacattcc
tgtaaatgtggcaggaataagaaaaccccagtttcccgctctcacctttga

KEGG   Homo sapiens (human): 6582Help
Entry
6582              CDS       T01001                                 

Gene name
SLC22A2, OCT2
Definition
(RefSeq) solute carrier family 22 member 2
  KO
K08199  MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    6582 (SLC22A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6582 (SLC22A2)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   6582 (SLC22A2)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family [TC:2.A.1.19]
    6582 (SLC22A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Sugar_tr MFS_1
Motif
Other DBs
NCBI-GeneID: 6582
NCBI-ProteinID: NP_003049
OMIM: 602608
HGNC: 10966
Ensembl: ENSG00000112499
Vega: OTTHUMG00000015950
Pharos: O15244(Tchem)
UniProt: O15244
Position
6q25.3
AA seq 555 aa AA seqDB search
MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELS
LRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLG
PCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCL
LTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIF
YQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAM
RIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSV
LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLA
SVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGII
TPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRKNKE
KMIYLQVQKLDIPLN
NT seq 1668 nt NT seq  +upstreamnt  +downstreamnt
atgcccaccaccgtggacgatgtcctggagcatggaggggagtttcactttttccagaag
caaatgtttttcctcttggctctgctctcggctaccttcgcgcccatctacgtgggcatc
gtcttcctgggcttcacccctgaccaccgctgccggagccccggagtggccgagctgagt
ctgcgctgcggctggagtcctgcagaggaactgaactacacggtgccgggcccaggacct
gcgggcgaagcctccccaagacagtgtaggcgctacgaggtggactggaaccagagcacc
ttcgactgcgtggaccccctggccagcctggacaccaacaggagccgcctgccactgggc
ccctgccgggacggctgggtgtacgagacgcctggctcgtccatcgtcaccgagtttaac
ctggtatgtgccaactcctggatgttggacctattccagtcatcagtgaatgtaggattc
tttattggctctatgagtatcggctacatagcagacaggtttggccgtaagctctgcctc
ctaactacagtcctcataaatgctgcagctggagttctcatggccatttccccaacctat
acgtggatgttaatttttcgcttaatccaaggactggtcagcaaagcaggctggttaata
ggctacatcctgattacagaatttgttgggcggagatatcggagaacagtggggattttt
taccaagttgcctatacagttgggctcctggtgctagctggggtggcttacgcacttcct
cactggaggtggttgcagttcacagtttctctgcccaacttcttcttcttgctctattac
tggtgcatacctgagtctcccaggtggctgatctcccagaataagaatgctgaagccatg
agaatcattaagcacatcgcaaagaaaaatggaaaatctctacccgcctcccttcagcgc
ctgagacttgaagaggaaactggcaagaaattgaacccttcatttcttgacttggtcaga
actcctcagataaggaaacatactatgatattgatgtacaactggttcacgagctctgtg
ctctaccagggcctcatcatgcacatgggccttgcaggtgacaatatctacctggatttc
ttctactctgccctggttgaattcccagctgccttcatgatcatcctcaccatcgaccgc
atcggacgccgttacccttgggctgcatcaaatatggttgcaggggcagcctgtctggcc
tcagtttttatacctggtgatctacaatggctaaaaattattatctcatgcttgggaaga
atggggatcacaatggcctatgagatagtctgcctggtcaatgctgagctgtaccccaca
ttcattaggaatcttggcgtccacatctgttcctcaatgtgtgacattggtggcatcatc
acgccattcctggtctaccggctcactaacatctggcttgagctcccgctgatggttttc
ggcgtgcttggcttggttgctggaggtctggtgctgttgcttccagaaactaaagggaaa
gctttgcctgagaccatcgaggaagccgaaaatatgcaaagaccaagaaaaaataaagaa
aagatgatttacctccaagttcagaaactagacattccattgaactaa

KEGG   Homo sapiens (human): 6583Help
Entry
6583              CDS       T01001                                 

Gene name
SLC22A4, DFNB60, OCTN1
Definition
(RefSeq) solute carrier family 22 member 4
  KO
K08202  MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Disease
H00286  Crohn disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    6583 (SLC22A4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6583 (SLC22A4)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   6583 (SLC22A4)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family [TC:2.A.1.19]
    6583 (SLC22A4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MFS_1 Sugar_tr
Motif
Other DBs
NCBI-GeneID: 6583
NCBI-ProteinID: NP_003050
OMIM: 604190
HGNC: 10968
Ensembl: ENSG00000197208
Vega: OTTHUMG00000059648
Pharos: Q9H015(Tbio)
UniProt: Q9H015
Position
5q31.1
AA seq 551 aa AA seqDB search
MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSS
AWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
QDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQ
TGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFA
VGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA
AKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALS
LDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPV
DYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVY
LGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGKKTRDSMET
EENPKVLITAF
NT seq 1656 nt NT seq  +upstreamnt  +downstreamnt
atgcgggactacgacgaggtgatcgccttcctgggcgagtgggggcccttccagcgcctc
atcttcttcctgctcagcgccagcatcatccccaatggcttcaatggtatgtcagtcgtg
ttcctggcggggaccccggagcaccgctgtcgagtgccggacgccgcgaacctgagcagc
gcctggcgcaacaacagtgtcccgctgcggctgcgggacggccgcgaggtgccccacagc
tgcagccgctaccggctcgccaccatcgccaacttctcggcgctcgggctggagccgggg
cgcgacgtggacctggggcagctggagcaggagagctgcctggatggctgggagttcagc
caggacgtctacctgtccaccgtcgtgaccgagtggaatctggtgtgtgaggacaactgg
aaggtgcccctcaccacctccctgttcttcgtaggcgtgctcctcggctccttcgtgtcc
gggcagctgtcagacaggtttggcaggaagaacgttctcttcgcaaccatggctgtacag
actggcttcagcttcctgcagattttctccatcagctgggagatgttcactgtgttattt
gtcatcgtgggcatgggccagatctccaactatgtggtagccttcatactaggaacagaa
attcttggcaagtcagttcgtattatattctctacattaggagtgtgcacattttttgca
gttggctatatgctgctgccactgtttgcttacttcatcagagactggcggatgctgctg
ctggcgctgacggtgccgggagtgctgtgtgtcccgctgtggtggttcattcctgaatct
ccccgatggctgatatcccagagaagatttagagaggctgaagatatcatccaaaaagct
gcaaaaatgaacaacatagctgtaccagcagtgatatttgattctgtggaggagctaaat
cccctgaagcagcagaaagctttcattctggacctgttcaggactcggaatattgccata
atgaccattatgtctttgctgctatggatgctgacctcagtgggttactttgctctgtct
ctggatgctcctaatttacatggagatgcctacctgaactgtttcctctctgccttgatt
gaaattccagcttacattacagcctggctgctattgcgaaccctgcccaggcgttatatc
atagctgcagtactgttctggggaggaggtgtgcttctcttcattcaactggtacctgtg
gattattacttcttatccattggtctggtcatgctgggaaaatttgggatcacctctgct
ttctccatgctgtatgtcttcactgctgagctctacccaaccctggtcaggaacatggcg
gtgggggtcacatccacggcctccagagtgggcagcatcattgccccctactttgtttac
ctcggtgcttacaacagaatgctgccctacatcgtcatgggtagtctgactgtcctgatt
ggaatcctcaccctttttttccctgaaagtttgggaatgactcttccagaaaccttagag
cagatgcagaaagtgaaatggttcagatctgggaaaaaaacaagagactcaatggagaca
gaagaaaatcccaaggttctaataactgcattctga

KEGG   Homo sapiens (human): 6584Help
Entry
6584              CDS       T01001                                 

Gene name
SLC22A5, CDSP, OCTN2
Definition
(RefSeq) solute carrier family 22 member 5
  KO
K08202  MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Network
nt06020  beta-Oxidation in mitochondria
  Element
N00812  Transport of carnitine
N00813  Mutation-inactivated SLC22A5 to transport of carnitine
Disease
H00286  Crohn disease
H00525  Disorders of mitochondrial fatty-acid oxidation
H01589  Systemic primary carnitine deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    6584 (SLC22A5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6584 (SLC22A5)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   6584 (SLC22A5)
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family [TC:2.A.1.19]
    6584 (SLC22A5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Sugar_tr MFS_1
Motif
Other DBs
NCBI-GeneID: 6584
NCBI-ProteinID: NP_003051
OMIM: 603377
HGNC: 10969
Ensembl: ENSG00000197375
Vega: OTTHUMG00000059634
Pharos: O76082(Tbio)
UniProt: O76082
Position
5q31.1
AA seq 557 aa AA seqDB search
MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSS
AWRNHTVPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS
QDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQ
TGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYA
FGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKA
AKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFG
LSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLV
PPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYF
VYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTR
MLKDGQERPTILKSTAF
NT seq 1674 nt NT seq  +upstreamnt  +downstreamnt
atgcgggactacgacgaggtgaccgccttcctgggcgagtgggggcccttccagcgcctc
atcttcttcctgctcagcgccagcatcatccccaatggcttcaccggcctgtcctccgtg
ttcctgatagcgaccccggagcaccgctgccgggtgccggacgccgcgaacctgagcagc
gcctggcgcaaccacactgtcccactgcggctgcgggacggccgcgaggtgccccacagc
tgccgccgctaccggctcgccaccatcgccaacttctcggcgcttgggctggagccgggg
cgcgacgtggacctggggcagctggagcaggagagctgtctggatggctgggagttcagt
caggacgtctacctgtccaccattgtgaccgagtggaacctggtgtgtgaggacgactgg
aaggccccactcacaatctccttgttcttcgtgggtgtgctgttgggctccttcatttca
gggcagctgtcagacaggtttggccggaagaatgtgctgttcgtgaccatgggcatgcag
acaggcttcagcttcctgcagatcttctcgaagaattttgagatgtttgtcgtgctgttt
gtccttgtaggcatgggccagatctccaactatgtggcagcatttgtcctggggacagaa
attcttggcaagtcagttcgtataatattctctacgttaggagtgtgcatattttatgca
tttggctacatggtgctgccactgtttgcttacttcatccgagactggcggatgctgctg
gtggcgctgacgatgccgggggtgctatgcgtggcactctggtggttcatccctgagtcc
ccccgatggctcatctctcagggacgatttgaagaggcagaggtgatcatccgcaaggct
gccaaagccaatgggattgttgtgccttccactatctttgacccgagtgagttacaagac
ctaagttccaagaagcagcagtcccacaacattctggatctgcttcgaacctggaatatc
cggatggtcaccatcatgtccataatgctgtggatgaccatatcagtgggctattttggg
ctttcgcttgatactcctaacttgcatggggacatctttgtgaactgcttcctttcagcg
atggttgaagtcccagcatatgtgttggcctggctgctgctgcaatatttgccccggcgc
tattccatggccactgccctcttcctgggtggcagtgtccttctcttcatgcagctggta
cccccagacttgtattatttggctacagtcctggtgatggtgggcaagtttggagtcacg
gctgccttttccatggtctacgtgtacacagccgagctgtatcccacagtggtgagaaac
atgggtgtgggagtcagctccacagcatcccgcctgggcagcatcctgtctccctacttc
gtttaccttggtgcctacgaccgcttcctgccctacattctcatgggaagtctgaccatc
ctgacagccatcctcaccttgtttctcccagagagcttcggtaccccactcccagacacc
attgaccagatgctaagagtcaaaggaatgaaacacagaaaaactccaagtcacacaagg
atgttaaaagatggtcaagaaaggcccacaatccttaaaagcacagccttctaa

KEGG   Homo sapiens (human): 80736Help
Entry
80736             CDS       T01001                                 

Gene name
SLC44A4, C6orf29, CTL4, DFNA72, NG22, TPPT, hTPPT1
Definition
(RefSeq) solute carrier family 44 member 4
  KO
K15377  solute carrier family 44 (choline transporter-like protein), member 2/4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    80736 (SLC44A4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    80736 (SLC44A4)
   04147 Exosome [BR:hsa04147]
    80736 (SLC44A4)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC44: Choline-like transporter
   80736 (SLC44A4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   80736 (SLC44A4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Choline_transpo
Motif
Other DBs
NCBI-GeneID: 80736
NCBI-ProteinID: NP_079533
OMIM: 606107
HGNC: 13941
Ensembl: ENSG00000204385
Vega: OTTHUMG00000031133
Pharos: Q53GD3(Tbio)
UniProt: Q53GD3 A0A140VJH4
Position
6p21.33
AA seq 710 aa AA seqDB search
MGGKQRDEDDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGD
PRQVLYPRNSTGAYCGMGENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSC
PEDPWTVGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGR
CFPWTNVTPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVAL
VLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLS
AYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLV
TFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCP
GLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQ
DIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQNPVARCIMCC
FKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLF
FGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFG
MCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKKRKK
NT seq 2133 nt NT seq  +upstreamnt  +downstreamnt
atggggggaaagcagcgggacgaggatgacgaggcctacgggaagccagtcaaatacgac
ccctcctttcgaggccccatcaagaacagaagctgcacagatgtcatctgctgcgtcctc
ttcctgctcttcattctaggttacatcgtggtggggattgtggcctggttgtatggagac
ccccggcaagtcctctaccccaggaactctactggggcctactgtggcatgggggagaac
aaagataagccgtatctcctgtacttcaacatcttcagctgcatcctgtccagcaacatc
atctcagttgctgagaacggcctacagtgccccacaccccaggtgtgtgtgtcctcctgc
ccggaggacccatggactgtgggaaaaaacgagttctcacagactgttggggaagtcttc
tatacaaaaaacaggaacttttgtctgccaggggtaccctggaatatgacggtgatcaca
agcctgcaacaggaactctgccccagtttcctcctcccctctgctccagctctggggcgc
tgctttccatggaccaacgttactccaccggcgctcccagggatcaccaatgacaccacc
atacagcaggggatcagcggtcttattgacagcctcaatgcccgagacatcagtgttaag
atctttgaagattttgcccagtcctggtattggattcttgttgccctgggggtggctctg
gtcttgagcctactgtttatcttgcttctgcgcctggtggctgggcccctggtgctggtg
ctgatcctgggagtgctgggcgtgctggcatacggcatctactactgctgggaggagtac
cgagtgctgcgggacaagggcgcctccatctcccagctgggtttcaccaccaacctcagt
gcctaccagagcgtgcaggagacctggctggccgccctgatcgtgttggcggtgcttgaa
gccatcctgctgctgatgctcatcttcctgcggcagcggattcgtattgccatcgccctc
ctgaaggaggccagcaaggctgtgggacagatgatgtctaccatgttctacccactggtc
acctttgtcctcctcctcatctgcattgcctactgggccatgactgctctgtacctggct
acatcggggcaaccccagtatgtgctctgggcatccaacatcagctcccccggctgtgag
aaagtgccaataaatacatcatgcaaccccacggcccaccttgtgaactcctcgtgccca
gggctgatgtgcgtcttccagggctactcatccaaaggcctaatccaacgttctgtcttc
aatctgcaaatctatggggtcctggggctcttctggacccttaactgggtactggccctg
ggccaatgcgtcctcgctggagcctttgcctccttctactgggccttccacaagccccag
gacatccctaccttccccttaatctctgccttcatccgcacactccgttaccacactggg
tcattggcatttggagccctcatcctgacccttgtgcagatagcccgggtcatcttggag
tatattgaccacaagctcagaggagtgcagaaccctgtagcccgctgcatcatgtgctgt
ttcaagtgctgcctctggtgtctggaaaaatttatcaagttcctaaaccgcaatgcatac
atcatgatcgccatctacgggaagaatttctgtgtctcagccaaaaatgcgttcatgcta
ctcatgcgaaacattgtcagggtggtcgtcctggacaaagtcacagacctgctgctgttc
tttgggaagctgctggtggtcggaggcgtgggggtcctgtccttcttttttttctccggt
cgcatcccggggctgggtaaagactttaagagcccccacctcaactattactggctgccc
atcatgacctccatcctgggggcctatgtcatcgccagcggcttcttcagcgttttcggc
atgtgtgtggacacgctcttcctctgcttcctggaagacctggagcggaacaacggctcc
ctggaccggccctactacatgtccaagagccttctaaagattctgggcaagaagaacgag
gcgcccccggacaacaagaagaggaagaagtga

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