KEGG   Homo sapiens (human): 129807Help
Entry
129807            CDS       T01001                                 

Gene name
NEU4
Definition
(RefSeq) neuraminidase 4
  KO
K12357  sialidase-2/3/4 [EC:3.2.1.18]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00511  Other glycan degradation
hsa00600  Sphingolipid metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    129807 (NEU4)
  09107 Glycan biosynthesis and metabolism
   00511 Other glycan degradation
    129807 (NEU4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.18  exo-alpha-sialidase
     129807 (NEU4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: BNR_2 BNR_3 BNR
Motif
Other DBs
NCBI-GeneID: 129807
NCBI-ProteinID: NP_001161072
OMIM: 608527
HGNC: 21328
Ensembl: ENSG00000204099
Vega: OTTHUMG00000133412
Pharos: Q8WWR8(Tchem)
UniProt: Q8WWR8 B3KR54
Position
2q37.3
AA seq 484 aa AA seqDB search
MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGT
LAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRN
AARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYR
VDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCN
ARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGP
GSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSW
TLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYS
DLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGC
CWPS
NT seq 1455 nt NT seq  +upstreamnt  +downstreamnt
atgggggtccctcgtaccccttcacggacagtgctcttcgagcgggagaggacgggcctg
acctaccgcgtgccctcgctgctccccgtgccccccgggcccaccctgctggcctttgtg
gagcagcggctcagccctgacgactcccacgcccaccgcctggtgctgaggaggggcacg
ctggccgggggctccgtgcggtggggtgccctgcacgtgctggggacagcagccctggcg
gagcaccggtccatgaacccctgccctgtgcacgatgctggcacgggcaccgtcttcctc
ttcttcatcgcggtgctgggccacacgcctgaggccgtgcagatcgccacgggaaggaac
gccgcgcgcctctgctgtgtggccagccgtgacgccggcctctcgtggggcagcgcccgg
gacctcaccgaggaggccatcggtggtgccgtgcaggactgggccacattcgctgtgggt
cccggccacggtgtgcagctgccctcaggccgcctgctggtacccgcctacacctaccgc
gtggaccgccgagagtgttttggcaagatctgccggaccagccctcactccttcgccttc
tacagcgatgaccacggccgcacctggcgctgtggaggcctcgtgcccaacctgcgctca
ggcgagtgccagctggcagcggtggacggtgggcaggccggcagcttcctctactgcaat
gcccggagcccactgggcagccgtgtgcaggcgctcagcactgacgagggcacctccttc
ctgcccgcagagcgcgtggcttccctgcccgagactgcctggggctgccagggcagcatc
gtgggcttcccagcccccgcccccaacaggccacgggatgacagttggtcagtgggcccc
gggagtcccctccagcctccactcctcggtcctggagtccacgaacccccagaggaggct
gctgtagacccccgtggaggccaggtgcctggtgggcccttcagccgtctgcagcctcgg
ggggatggccccaggcagcctggccccaggcctggggtcagtggggatgtggggtcctgg
accctggcactccccatgccctttgctgccccgccccagagccccacgtggctgctgtac
tcccacccagtggggcgcagggctcggctacacatgggtatccgcctgagccagtccccg
ctggacccgcgcagctggacagagccctgggtgatctacgagggccccagcggctactcc
gacctggcgtccatcgggccggcccctgaggggggcctggtttttgcctgcctgtacgag
agcggggccaggacctcctatgatgagatttccttttgtacattctccctgcgtgaggtc
ctggagaacgtgcccgccagccccaaaccgcccaaccttggggacaagcctcgggggtgc
tgctggccctcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (39)   
   RefSeq(nuc) (5)   
   GenBank (17)   
   EMBL (17)   
Protein domain (3)   
   Pfam (3)   
All databases (93)   

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