KEGG   Homo sapiens (human): 134526
Entry
134526            CDS       T01001                                 
Symbol
ACOT12, CACH-1, Cach, STARD15, THEAL
Name
(RefSeq) acyl-CoA thioesterase 12
  KO
K01067  acetyl-CoA hydrolase [EC:3.1.2.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00620  Pyruvate metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    134526 (ACOT12)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.1  acetyl-CoA hydrolase
     134526 (ACOT12)
SSDB
Motif
Pfam: 4HBT START Polyketide_cyc2
Other DBs
NCBI-GeneID: 134526
NCBI-ProteinID: NP_570123
OMIM: 614315
HGNC: 24436
Ensembl: ENSG00000172497
UniProt: Q8WYK0
Structure
Position
5:complement(81308609..81394134)
AA seq 555 aa
MERPAPGEVVMSQAIQPAHATARGELSAGQLLKWIDTTACLAAEKHAGVSCVTASVDDIQ
FEETARVGQVITIKAKVTRAFSTSMEISIKVMVQDMLTGIEKLVSVAFSTFVAKPVGKEK
IHLKPVTLLTEQDHVEHNLAAERRKVRLQHEDTFNNLMKESSKFDDLIFDEEEGAVSTRG
TSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCWAHPFLKSVDMFKFRGPST
VGDRLVFTAIVNNTFQTCVEVGVRVEAFDCQEWAEGRGRHINSAFLIYNAADDKENLITF
PRIQPISKDDFRRYRGAIARKRIRLGRKYVISHKEEVPLCIHWDISKQASLSDSNVEALK
KLAAKRGWEVTSTVEKIKIYTLEEHDVLSVWVEKHVGSPAHLAYRLLSDFTKRPLWDPHF
VSCEVIDWVSEDDQLYHITCPILNDDKPKDLVVLVSRRKPLKDGNTYTVAVKSVILPSVP
PSPQYIRSEIICAGFLIHAIDSNSCIVSYFNHMSASILPYFAGNLGGWSKSIEETAASCI
QFLENPPDDGFVSTF
NT seq 1668 nt   +upstreamnt  +downstreamnt
atggagcggccggcgcccggcgaggtggtcatgagccaagccatccagccggcgcacgcc
actgcgcgcggcgagctgagcgcggggcagctgctcaagtggatcgacaccaccgcctgc
ctggcggctgagaaacatgctggagtttcctgcgttacagcctcagtggatgacatacag
tttgaggagacagctagagttggacaagttataaccatcaaagcaaaagttactagagca
ttcagcacaagcatggagatcagtatcaaggtcatggtacaggatatgctcactggcatt
gagaagcttgttagtgtggctttctccacatttgtagccaaaccagttggaaaagaaaag
attcatttaaaaccagtcacacttctaactgaacaagatcatgtggaacataatctggct
gctgagagaaggaaagttcgattacaacatgaagatacctttaacaatttaatgaaggaa
agtagcaaatttgatgatctcatttttgatgaagaggaaggagcggtttccacaaggggc
acctccgttcagagcattgaactggtcctcccaccccatgcaaaccatcacggaaataca
tttggtggccagattatggcgtggatggagacagtggctactatttctgcaagccgcctg
tgttgggctcatccctttctgaagtccgtagatatgtttaagttccggggaccatctaca
gttggagatcgtcttgtcttcactgccattgtcaacaatacatttcagacctgtgttgaa
gttggagttcgcgtggaggcctttgactgtcaggaatgggccgagggccgagggcgtcac
atcaacagtgcttttctcatttacaatgctgctgatgataaggaaaatctcatcacgttt
cccagaatccaacccatttcaaaggatgatttcagacgctatcggggagctattgcacgc
aagcgaattcgcctaggcagaaaatatgttatttcccacaaagaagaggttccactttgc
atacactgggatatcagcaagcaggcatccctgagtgacagcaatgtggaggccctcaaa
aaactggcagccaaaaggggttgggaggttaccagcactgtggaaaagataaaaatatat
actctggaagagcatgatgttttatctgtttgggttgaaaagcacgtgggaagtccagca
catttggcttatcgtctcttgtctgactttacaaagcgacctttgtgggacccccatttt
gtgtcctgtgaagtcatagactgggtgagtgaagatgatcagctgtatcacatcacctgt
cctatactgaatgatgacaaacccaaagacttggtagtactcgtatcacgaagaaaaccc
ctcaaagatggtaacacttacacagtggcagtgaagtcggtcattttgccatcggtcccc
ccgtctccacagtacatcagaagtgaaatcatatgtgccggatttctcatccatgctatt
gacagcaattcatgcatcgtatcttactttaaccatatgtctgctagcatccttccttac
tttgctggaaatcttggtggctggtcaaaatccattgaagaaacagcagcctcttgtata
cagttcttagagaatcctcctgatgatgggtttgtaagcacattttaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (10)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (22)   
   RefSeq(nuc) (12)   
   GenBank (5)   
   EMBL (5)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (53)   

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