KEGG   Homo sapiens (human): 134526
Entry
134526            CDS       T01001                                 

Symbol
ACOT12, CACH-1, Cach, STARD15, THEAL
Name
(RefSeq) acyl-CoA thioesterase 12
  KO
K01067  acetyl-CoA hydrolase [EC:3.1.2.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00620  Pyruvate metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    134526 (ACOT12)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.1  acetyl-CoA hydrolase
     134526 (ACOT12)
SSDB
Motif
Pfam: 4HBT START Polyketide_cyc2 Polyketide_cyc
Other DBs
NCBI-GeneID: 134526
NCBI-ProteinID: NP_570123
OMIM: 614315
HGNC: 24436
Ensembl: ENSG00000172497
Vega: OTTHUMG00000131305
Pharos: Q8WYK0(Tbio)
UniProt: Q8WYK0
Structure
PDB: 
4MOB 4MOC 3B7K

Position
5q14.1
AA seq 555 aa
MERPAPGEVVMSQAIQPAHATARGELSAGQLLKWIDTTACLAAEKHAGVSCVTASVDDIQ
FEETARVGQVITIKAKVTRAFSTSMEISIKVMVQDMLTGIEKLVSVAFSTFVAKPVGKEK
IHLKPVTLLTEQDHVEHNLAAERRKVRLQHEDTFNNLMKESSKFDDLIFDEEEGAVSTRG
TSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCWAHPFLKSVDMFKFRGPST
VGDRLVFTAIVNNTFQTCVEVGVRVEAFDCQEWAEGRGRHINSAFLIYNAADDKENLITF
PRIQPISKDDFRRYRGAIARKRIRLGRKYVISHKEEVPLCIHWDISKQASLSDSNVEALK
KLAAKRGWEVTSTVEKIKIYTLEEHDVLSVWVEKHVGSPAHLAYRLLSDFTKRPLWDPHF
VSCEVIDWVSEDDQLYHITCPILNDDKPKDLVVLVSRRKPLKDGNTYTVAVKSVILPSVP
PSPQYIRSEIICAGFLIHAIDSNSCIVSYFNHMSASILPYFAGNLGGWSKSIEETAASCI
QFLENPPDDGFVSTF
NT seq 1668 nt   +upstreamnt  +downstreamnt
atggagcggccggcgcccggcgaggtggtcatgagccaagccatccagccggcgcacgcc
actgcgcgcggcgagctgagcgcggggcagctgctcaagtggatcgacaccaccgcctgc
ctggcggctgagaaacatgctggagtttcctgcgttacagcctcagtggatgacatacag
tttgaggagacagctagagttggacaagttataaccatcaaagcaaaagttactagagca
ttcagcacaagcatggagatcagtatcaaggtcatggtacaggatatgctcactggcatt
gagaagcttgttagtgtggctttctccacatttgtagccaaaccagttggaaaagaaaag
attcatttaaaaccagtcacacttctaactgaacaagatcatgtggaacataatctggct
gctgagagaaggaaagttcgattacaacatgaagatacctttaacaatttaatgaaggaa
agtagcaaatttgatgatctcatttttgatgaagaggaaggagcggtttccacaaggggc
acctccgttcagagcattgaactggtcctcccaccccatgcaaaccatcacggaaataca
tttggtggccagattatggcgtggatggagacagtggctactatttctgcaagccgcctg
tgttgggctcatccctttctgaagtccgtagatatgtttaagttccggggaccatctaca
gttggagatcgtcttgtcttcactgccattgtcaacaatacatttcagacctgtgttgaa
gttggagttcgcgtggaggcctttgactgtcaggaatgggccgagggccgagggcgtcac
atcaacagtgcttttctcatttacaatgctgctgatgataaggaaaatctcatcacgttt
cccagaatccaacccatttcaaaggatgatttcagacgctatcggggagctattgcacgc
aagcgaattcgcctaggcagaaaatatgttatttcccacaaagaagaggttccactttgc
atacactgggatatcagcaagcaggcatccctgagtgacagcaatgtggaggccctcaaa
aaactggcagccaaaaggggttgggaggttaccagcactgtggaaaagataaaaatatat
actctggaagagcatgatgttttatctgtttgggttgaaaagcacgtgggaagtccagca
catttggcttatcgtctcttgtctgactttacaaagcgacctttgtgggacccccatttt
gtgtcctgtgaagtcatagactgggtgagtgaagatgatcagctgtatcacatcacctgt
cctatactgaatgatgacaaacccaaagacttggtagtactcgtatcacgaagaaaaccc
ctcaaagatggtaacacttacacagtggcagtgaagtcggtcattttgccatcggtcccc
ccgtctccacagtacatcagaagtgaaatcatatgtgccggatttctcatccatgctatt
gacagcaattcatgcatcgtatcttactttaaccatatgtctgctagcatccttccttac
tttgctggaaatcttggtggctggtcaaaatccattgaagaaacagcagcctcttgtata
cagttcttagagaatcctcctgatgatgggtttgtaagcacattttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (18)   
   RefSeq(nuc) (8)   
   GenBank (5)   
   EMBL (5)   
Protein domain (4)   
   Pfam (4)   
All databases (57)   

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