KEGG   Homo sapiens (human): 1355
Entry
1355              CDS       T01001                                 
Symbol
COX15, CEMCOX2, HAS, MC4DN6
Name
(RefSeq) cytochrome c oxidase assembly homolog COX15
  KO
K02259  heme a synthase [EC:1.17.99.9]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa00860  Porphyrin metabolism
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
hsa04714  Thermogenesis
Module
hsa_M00154  Cytochrome c oxidase
Network
nt06529  Thermogenesis
  Element
N01691  mitochondrial complex - UCP1 in Thermogenesis
Disease
H01200  Fatal infantile cardioencephalomyopathy
H01368  Cytochrome c oxidase (COX) deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    1355 (COX15)
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    1355 (COX15)
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    1355 (COX15)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:hsa03029]
    1355 (COX15)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.99  With unknown physiological acceptors
    1.17.99.9  heme a synthase
     1355 (COX15)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitochondrial respiratory chain complex assembly factors
   Complex-IV assembly factors
    1355 (COX15)
SSDB
Motif
Pfam: COX15-CtaA DUF6220 Peptidase_S3
Other DBs
NCBI-GeneID: 1355
NCBI-ProteinID: NP_510870
OMIM: 603646
HGNC: 2263
Ensembl: ENSG00000014919
UniProt: Q7KZN9
Position
10:complement(99694293..99732127)
AA seq 410 aa
MQRLLFPPLRALKGRQYLPLLAPRAAPRAQCDCIRRPLRPGQYSTISEVALQSGRGTVSL
PSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAE
FQRYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRLVGLVYILPAAYFWRKGWLSRGM
KGRVLALCGLVCFQGLLGWYMVKSGLEEKSDSHDIPRVSQYRLAAHLGSALVLYCASLWT
SLSLLLPPHKLPETHQLLQLRRFAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESW
IPEDLFTFSPILRNVFENPTMVQFDHRILGITSVTAITVLYFLSRRIPLPRRTKMAAVTL
LALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLTGALWLMNELRRVPK
NT seq 1233 nt   +upstreamnt  +downstreamnt
atgcagcgattgctctttccgccgttgagggccttgaaggggaggcagtatctgccgctc
ctggctcctagggcagcgcctagagcacagtgtgattgcatcaggcgccctttgaggcca
gggcaatacagcaccatctctgaagtagctttgcaatctggaaggggtacagtgtccctt
ccctcaaaggctgctgagcgggtggtgggccgatggctcctggtctgcagtggaacagtg
gctggagcagttattcttggtggagtaactaggttgacagagtctggcctctcgatggta
gattggcatttaataaaggagatgaagccacctacaagccaagaggaatgggaagcagaa
ttccaaagataccagcaatttccagaatttaaaatcttgaatcatgatatgacactgaca
gaattcaagttcatctggtacatggagtactcacaccgaatgtggggtcgccttgtaggc
cttgtgtacatcctgcctgctgcctacttttggagaaagggctggctcagccgtggcatg
aaaggacgtgttcttgccctctgtggcctcgtctgcttccagggtctgttgggatggtat
atggtgaaaagtggactagaagaaaaatcagactcccatgacatccctcgggtcagtcag
taccgccttgctgcccacctgggatcagccctggttctttattgtgccagcttgtggacc
tcactgtcactgctactccctccgcacaagttgcctgaaacccaccaactcctacagttg
agacgatttgctcatggaacagcaggtctggtgttccttacggccctctcaggggctttt
gtggcagggctagatgctgggcttgtttataactcctttcccaaaatgggagaatcctgg
atcccggaggacctctttaccttctcccccatcctgaggaatgtttttgagaatcccacc
atggtgcagtttgatcaccggattctgggaatcacttcagtcactgccattacagtgctc
tacttcctctctcggagaattccccttcctagaaggaccaagatggcagcagtgactctg
ctggctttggcgtatacacaggtgggcttgggcatcagcacgctgctgatgtatgtccca
actcctctggccgccactcaccagtcaggctccttggctttgctcactggtgctctttgg
ctgatgaatgaactccgaagagtcccaaaatga

  All links  
Disease (3)   
   OMIM (3)   
Gene (14)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (37)   
   RefSeq(nuc) (13)   
   GenBank (12)   
   EMBL (12)   
Protein domain (3)   
   Pfam (3)   
All databases (71)   

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