KEGG   Homo sapiens (human): 1360
Entry
1360              CDS       T01001                                 

Gene name
CPB1, CPB, PASP, PCPB
Definition
(RefSeq) carboxypeptidase B1
  KO
K01291  carboxypeptidase B [EC:3.4.17.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04972  Pancreatic secretion
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    1360 (CPB1)
   04974 Protein digestion and absorption
    1360 (CPB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    1360 (CPB1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.17  Metallocarboxypeptidases
    3.4.17.2  carboxypeptidase B
     1360 (CPB1)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M14: carboxypeptidase A family
   1360 (CPB1)
SSDB
Motif
Pfam: Peptidase_M14 Propep_M14 Intimin_C GATase1_like
Other DBs
NCBI-GeneID: 1360
NCBI-ProteinID: NP_001862
OMIM: 114852
HGNC: 2299
Ensembl: ENSG00000153002
Vega: OTTHUMG00000159520
Pharos: P15086(Tchem)
UniProt: P15086
Structure
PDB: 
1KWM 1ZLI

Position
3q24
AA seq 417 aa
MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ
IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN
KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREW
ISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTH
TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAY
LTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAG
GSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY
NT seq 1254 nt   +upstreamnt  +downstreamnt
atgttggcactcttggttctggtgactgtggccctggcatctgctcatcatggtggtgag
cactttgaaggcgagaaggtgttccgtgttaacgttgaagatgaaaatcacattaacata
atccgcgagttggccagcacgacccagattgacttctggaagccagattctgtcacacaa
atcaaacctcacagtacagttgacttccgtgttaaagcagaagatactgtcactgtggag
aatgttctaaagcagaatgaactacaatacaaggtactgataagcaacctgagaaatgtg
gtggaggctcagtttgatagccgggttcgtgcaacaggacacagttatgagaagtacaac
aagtgggaaacgatagaggcttggactcaacaagtcgccactgagaatccagccctcatc
tctcgcagtgttatcggaaccacatttgagggacgcgctatttacctcctgaaggttggc
aaagctggacaaaataagcctgccattttcatggactgtggtttccatgccagagagtgg
atttctcctgcattctgccagtggtttgtaagagaggctgttcgtacctatggacgtgag
atccaagtgacagagcttctcgacaagttagacttttatgtcctgcctgtgctcaatatt
gatggctacatctacacctggaccaagagccgattttggagaaagactcgctccacccat
actggatctagctgcattggcacagaccccaacagaaattttgatgctggttggtgtgaa
attggagcctctcgaaacccctgtgatgaaacttactgtggacctgccgcagagtctgaa
aaggagaccaaggccctggctgatttcatccgcaacaaactctcttccatcaaggcatat
ctgacaatccactcgtactcccaaatgatgatctacccttactcatatgcttacaaactc
ggtgagaacaatgctgagttgaatgccctggctaaagctactgtgaaagaacttgcctca
ctgcacggcaccaagtacacatatggcccgggagctacaacaatctatcctgctgctggg
ggctctgacgactgggcttatgaccaaggaatcagatattccttcacctttgaacttcga
gatacaggcagatatggctttctccttccagaatcccagatccgggctacctgcgaggag
accttcctggcaatcaagtatgttgccagctacgtcctggaacacctgtactag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
Protein domain (4)   
   Pfam (4)   
All databases (42)   

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KEGG   Homo sapiens (human): 1361
Entry
1361              CDS       T01001                                 

Gene name
CPB2, CPU, PCPB, TAFI
Definition
(RefSeq) carboxypeptidase B2
  KO
K01300  carboxypeptidase B2 [EC:3.4.17.20]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
hsa04972  Pancreatic secretion
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    1361 (CPB2)
  09154 Digestive system
   04972 Pancreatic secretion
    1361 (CPB2)
   04974 Protein digestion and absorption
    1361 (CPB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    1361 (CPB2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.17  Metallocarboxypeptidases
    3.4.17.20  carboxypeptidase U
     1361 (CPB2)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M14: carboxypeptidase A family
   1361 (CPB2)
SSDB
Motif
Pfam: Peptidase_M14 Propep_M14
Other DBs
NCBI-GeneID: 1361
NCBI-ProteinID: NP_001863
OMIM: 603101
HGNC: 2300
Ensembl: ENSG00000080618
Vega: OTTHUMG00000016867
Pharos: Q96IY4(Tchem)
UniProt: Q96IY4
Structure
PDB: 

Position
13q14.13
AA seq 423 aa
MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK
NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSE
TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI
RNV
NT seq 1272 nt   +upstreamnt  +downstreamnt
atgaagctttgcagccttgcagtccttgtacccattgttctcttctgtgagcagcatgtc
ttcgcgtttcagagtggccaagttctagctgctcttcctagaacctctaggcaagttcaa
gttctacagaatcttactacaacatatgagattgttctctggcagccggtaacagctgac
cttattgtgaagaaaaaacaagtccatttttttgtaaatgcatctgatgtcgacaatgtg
aaagcccatttaaatgtgagcggaattccatgcagtgtcttgctggcagatgtggaagat
cttattcaacagcagatttccaacgacacagtcagcccccgagcctccgcatcgtactat
gaacagtatcactcactaaatgaaatctattcttggatagaatttataactgagaggcat
cctgatatgcttacaaaaatccacattggatcctcatttgagaagtacccactctatgtt
ttaaaggtttctggaaaagaacaagcagccaaaaatgccatatggattgactgtggaatc
catgccagagaatggatctctcctgctttctgcttgtggttcataggccatataactcaa
ttctatgggataatagggcaatataccaatctcctgaggcttgtggatttctatgttatg
ccagtggttaatgtggatggttatgactactcatggaaaaagaatcgaatgtggagaaag
aaccgttctttctatgcgaacaatcattgcatcggaacagacctgaataggaactttgct
tccaaacactggtgtgaggaaggtgcatccagttcctcatgctcggaaacctactgtgga
ctttatcctgagtcagaaccagaagtgaaggcagtggctagtttcttgagaagaaatatc
aaccagattaaagcatacatcagcatgcattcatactcccagcatatagtgtttccatat
tcctatacacgaagtaaaagcaaagaccatgaggaactgtctctagtagccagtgaagca
gttcgtgctattgagaaaattagtaaaaataccaggtatacacatggccatggctcagaa
accttatacctagctcctggaggtggggacgattggatctatgatttgggcatcaaatat
tcgtttacaattgaacttcgagatacgggcacatacggattcttgctgccggagcgttac
atcaaacccacctgtagagaagcttttgccgctgtctctaaaatagcttggcatgtcatt
aggaatgtttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (17)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (20)   
   RefSeq(nuc) (4)   
   GenBank (8)   
   EMBL (8)   
Protein domain (2)   
   Pfam (2)   
All databases (65)   

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