KEGG   Homo sapiens (human): 1392
Entry
1392              CDS       T01001                                 
Symbol
CRH, CRF, CRH1
Name
(RefSeq) corticotropin releasing hormone
  KO
K05256  corticotropin-releasing hormone
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04081  Hormone signaling
hsa04730  Long-term depression
hsa04934  Cushing syndrome
hsa05034  Alcoholism
Network
nt06310  CRH-ACTH-cortisol signaling
nt06360  Cushing syndrome
  Element
N00324  CRHR-PKA-ACTH signaling pathway
N00327  Mutation-inactivated PRKAR1A to CRHR-PKA-ACTH signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    1392 (CRH)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1392 (CRH)
   04081 Hormone signaling
    1392 (CRH)
 09150 Organismal Systems
  09156 Nervous system
   04730 Long-term depression
    1392 (CRH)
 09160 Human Diseases
  09165 Substance dependence
   05034 Alcoholism
    1392 (CRH)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    1392 (CRH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    1392 (CRH)
Cytokines and neuropeptides [BR:hsa04052]
 Neuropeptides
  GPCR binding
   1392 (CRH)
SSDB
Motif
Pfam: CRF
Other DBs
NCBI-GeneID: 1392
NCBI-ProteinID: NP_000747
OMIM: 122560
HGNC: 2355
Ensembl: ENSG00000147571
CPD: C16079
UniProt: P06850 A0A0S2Z478
Structure
Position
8:complement(66176376..66178464)
AA seq 196 aa
MRLPLLVSAGVLLVALLPCPPCRALLSRGPVPGARQAPQHPQPLDFFQPPPQSEQPQQPQ
ARPVLLRMGEEYFLRLGNLNKSPAAPLSPASSLLAGGSGSRPSPEQATANFFRVLLQQLL
LPRRSLDSPAALAERGARNALGGHQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQL
AQQAHSNRKLMEIIGK
NT seq 591 nt   +upstreamnt  +downstreamnt
atgcggctgccgctgcttgtgtccgcgggagtcctgctggtggctctcctgccctgcccg
ccatgcagggcgctcctgagccgcgggccggtcccgggagctcggcaggcgccgcagcac
cctcagcccttggatttcttccagccgccgccgcagtccgagcagccccagcagccgcag
gctcggccggtcctgctccgcatgggagaggagtacttcctccgcctggggaacctcaac
aagagcccggccgctcccctttcgcccgcctcctcgctcctcgccggaggcagcggcagc
cgcccttcgccggaacaggcgaccgccaactttttccgcgtgttgctgcagcagctgctg
ctgcctcggcgctcgctcgacagccccgcggctctcgcggagcgcggcgctaggaatgcc
ctcggcggccaccaggaggcaccggagagagaaaggcggtccgaggagcctcccatctcc
ctggatctcaccttccacctcctccgggaagtcttggaaatggccagggccgagcagtta
gcacagcaagctcacagcaacaggaaactcatggagattattgggaaataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (11)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (18)   
   RefSeq(nuc) (4)   
   GenBank (7)   
   EMBL (7)   
3D Structure (5)   
   PDB (5)   
Protein domain (1)   
   Pfam (1)   
All databases (43)   

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