KEGG   Homo sapiens (human): 1407
Entry
1407              CDS       T01001                                 

Gene name
CRY1, DSPD, PHLL1
Definition
(RefSeq) cryptochrome circadian regulator 1
  KO
K02295  cryptochrome
Organism
hsa  Homo sapiens (human)
Pathway
hsa04710  Circadian rhythm
Disease
H00689  Delayed sleep phase syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    1407 (CRY1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    1407 (CRY1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   Direct repair
    1407 (CRY1)
SSDB
Motif
Pfam: FAD_binding_7 DNA_photolyase Peripla_BP_6
Other DBs
NCBI-GeneID: 1407
NCBI-ProteinID: NP_004066
OMIM: 601933
HGNC: 2384
Ensembl: ENSG00000008405
Vega: OTTHUMG00000170005
Pharos: Q16526(Tbio)
UniProt: Q16526 A2I2P0
Position
12q23.3
AA seq 586 aa
MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLE
DLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEA
GVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTT
PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMN
ANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAA
TNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA
VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGR
RTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLN
IERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYA
HGDSQQTHLLKQGRSSMGTGLSGGKRPSQEEDTQSIGPKVQRQSTN
NT seq 1761 nt   +upstreamnt  +downstreamnt
atgggggtgaacgccgtgcactggttccgaaaggggctccggctccacgacaaccccgcc
ctgaaggagtgcattcagggcgccgacaccatccgctgcgtctacatcctggacccctgg
ttcgccggctcctccaatgtgggcatcaacaggtggcgatttttgcttcagtgtcttgag
gatcttgatgccaatctacgaaaattaaactcccgtctgtttgtgattcgtggacaacca
gcagatgtgtttcccaggcttttcaaggaatggaacattactaaactttcaattgagtat
gattctgagccctttggaaaggaacgagacgcagctattaagaaactggcaactgaagct
ggagtagaagtcattgtaagaatttcacatacattatatgacctagacaagatcatagaa
ctcaatggtggacaaccgcctctaacttataaaagattccagactctcatcagcaaaatg
gaaccactagagataccagtagagacaattacttcagaagtgatagaaaagtgcacaact
cctctgtctgatgaccatgatgagaaatatggagtcccttcactggaagagctaggtttt
gatacagatggcttatcctctgcagtgtggccaggtggagaaactgaagcacttactcgt
ttggaaaggcatttggaaagaaaagcttgggtggcaaattttgaaagacctcgaatgaat
gcgaattctctgcttgcaagccctactggacttagtccttatctccgatttggttgtttg
tcatgtcgactgttttacttcaaactaacagatctctacaaaaaggtaaagaagaacagt
tcccctcccctttccctttatgggcaactgttatggcgtgaatttttctatacagcagca
acaaataatccacgctttgataaaatggaaggaaaccctatctgtgttcagattccttgg
gataaaaatcctgaggctttagccaaatgggcggaaggccggacaggctttccatggatt
gatgccatcatgacacagcttcgtcaggagggttggattcatcatctagccaggcatgca
gttgcttgcttcctgacacgaggggacctgtggattagttgggaagaaggaatgaaggta
tttgaagaattattgcttgatgcagattggagcataaatgctggaagttggatgtggctg
tcttgtagttccttttttcaacagttttttcactgctattgccctgttggttttggtagg
agaacagatcccaatggagactatatcaggcgttatttgcctgtcctaagaggcttccct
gcaaaatatatctatgatccctggaatgcaccagaaggtatccaaaaggtagccaaatgt
ttgataggagttaattatcctaaaccaatggtgaaccatgctgaggcaagccgtttgaat
atcgaaaggatgaaacagatctatcagcagctttcacgatatagaggactaggtcttctg
gcatcagtaccttctaatcctaatgggaatggaggcttcatgggatattctgcagaaaat
atcccaggttgtagcagcagtggaagttgctctcaagggagtggtattttacactatgct
catggcgacagtcagcaaactcacctgttgaagcaaggaagaagctccatgggcactggt
ctcagtggtgggaaacgtcctagtcaggaagaggacacacagagtattggtcctaaagtc
cagagacagagcactaattag

KEGG   Homo sapiens (human): 1408
Entry
1408              CDS       T01001                                 

Gene name
CRY2, HCRY2, PHLL2
Definition
(RefSeq) cryptochrome circadian regulator 2
  KO
K02295  cryptochrome
Organism
hsa  Homo sapiens (human)
Pathway
hsa04710  Circadian rhythm
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    1408 (CRY2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    1408 (CRY2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   Direct repair
    1408 (CRY2)
SSDB
Motif
Pfam: FAD_binding_7 DNA_photolyase Peripla_BP_6 ROQ_II
Other DBs
NCBI-GeneID: 1408
NCBI-ProteinID: NP_066940
OMIM: 603732
HGNC: 2385
Ensembl: ENSG00000121671
Vega: OTTHUMG00000153225
Pharos: Q49AN0(Tbio)
UniProt: Q49AN0 A0A0D2X7Z3 A2I2P1
Position
11p11.2
AA seq 593 aa
MAATVATAAAVAPAPAPGTDSASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWF
AASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYD
SEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQAIISRME
LPKKPVGLVTSQQMESCRAEIQENHDETYGVPSLEELGFPTEGLGPAVWQGGETEALARL
DKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNST
PPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWID
AIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLS
CSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKAFPSRYIYEPWNAPESIQKAAKCI
IGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPSSSQ
AGSMSSAGPRPLPSGPASPKRKLEAAEEPPGEELSKRARVAELPTPELPSKDA
NT seq 1782 nt   +upstreamnt  +downstreamnt
atggcggcgactgtggcgacggcggcagctgtggccccggcgccagcgcccggcacggac
agcgcctcttcggtgcactggttccgcaaagggctgcgactccacgacaacccggcgttg
ctggcggccgtgcgcggggcgcgctgcgtgcgctgcgtttacattctcgacccgtggttc
gcggcctcctcctcagtcgggatcaaccgatggaggttcctacttcagtctctggaagat
ttggacacaagtttaaggaaactgaactcccgcctgtttgtagtccggggacagccagcc
gacgtgttcccaaggctgttcaaggaatggggagtgacccgcttgacctttgaatatgac
tctgaaccctttgggaaagaacgggatgcagccatcatgaagatggccaaggaggctggt
gtggaagtagtgacggagaattctcataccctctatgacctggacaggatcattgagctg
aatgggcagaagccaccccttacatacaagcgctttcaggccatcatcagccgcatggag
ctgcccaagaagccagtgggcttggtgaccagccagcagatggagagctgcagggccgag
atccaggagaaccacgacgagacctacggcgtgccctccctggaggagctggggttcccc
actgaaggacttggtccagctgtctggcagggaggagagacagaagctctggcccgcctg
gataagcacttggaacggaaggcctgggttgccaactatgagagaccccgaatgaacgcc
aactccctcctggccagccccacaggcctcagcccctacctgcgctttggttgtctctcc
tgccgcctcttctactaccgcctgtgggacctgtataaaaaggtgaagcggaacagcaca
cctcccctctccctatttgggcaactcctatggcgagagttcttctacacggcagctacc
aacaaccccaggtttgaccgcatggaggggaaccccatctgcatccagatcccctgggac
cgcaatcctgaggccctggccaagtgggctgagggcaagacaggcttcccttggattgat
gccatcatgacccaactgaggcaggagggctggatccaccacctggcccggcatgccgtg
gcctgcttcctgacccgcggggacctctgggtcagctgggagagcggggtccgggtattt
gatgagctgctcctggatgcagatttcagcgtgaacgcaggcagctggatgtggctgtcc
tgcagtgctttcttccagcagttcttccactgctactgccctgtgggctttggccgtcgc
acggaccccagtggggactacatcaggcgatacctgcccaaattgaaagcgttcccctct
cgatacatctatgagccctggaatgccccagagtcaattcagaaggcagccaagtgcatc
attggtgtggactacccacggcccatcgtcaaccatgccgagaccagccggcttaacatt
gaacgaatgaagcagatttaccagcagctttcgcgctaccggggactctgtctactggca
tctgtcccttcctgtgtggaagacctcagtcaccctgtggcagagcccagctcgagccag
gctggcagcatgagcagtgcaggcccaagaccactacccagtggcccagcatcccccaaa
cgcaagctggaagcagccgaggaaccacctggtgaagaactcagcaaacgggcccgggtg
gcagagttgccaaccccagagctgccgagcaaggatgcctga

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