KEGG   Homo sapiens (human): 1410
Entry
1410              CDS       T01001                                 

Gene name
CRYAB, CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2
Definition
(RefSeq) crystallin alpha B
  KO
K09542  crystallin, alpha B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04213  Longevity regulating pathway - multiple species
Disease
H00595  Myofibrillar myopathies
H01202  Cataract
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    1410 (CRYAB)
 09150 Organismal Systems
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    1410 (CRYAB)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    1410 (CRYAB)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1410 (CRYAB)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP20
   1410 (CRYAB)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   1410 (CRYAB)
SSDB
Motif
Pfam: Crystallin HSP20 ArsA_HSP20
Other DBs
NCBI-GeneID: 1410
NCBI-ProteinID: NP_001276736
OMIM: 123590
HGNC: 2389
Ensembl: ENSG00000109846
Vega: OTTHUMG00000166885
Pharos: P02511(Tbio)
UniProt: P02511 V9HW27
Structure
PDB: 

Position
11q23.1
AA seq 175 aa
MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSW
FDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHR
KYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
NT seq 528 nt   +upstreamnt  +downstreamnt
atggacatcgccatccaccacccctggatccgccgccccttctttcctttccactccccc
agccgcctctttgaccagttcttcggagagcacctgttggagtctgatcttttcccgacg
tctacttccctgagtcccttctaccttcggccaccctccttcctgcgggcacccagctgg
tttgacactggactctcagagatgcgcctggagaaggacaggttctctgtcaacctggat
gtgaagcacttctccccagaggaactcaaagttaaggtgttgggagatgtgattgaggtg
catggaaaacatgaagagcgccaggatgaacatggtttcatctccagggagttccacagg
aaataccggatcccagctgatgtagaccctctcaccattacttcatccctgtcatctgat
ggggtcctcactgtgaatggaccaaggaaacaggtctctggccctgagcgcaccattccc
atcacccgtgaagagaagcctgctgtcaccgcagcccccaagaaatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (7)   
   KEGG DISEASE (2)   
   OMIM (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (155)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (132)   
   OC (1)   
   PHAROS (1)   
   PROTHERM (15)   
   VEGA (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (50)   
   RefSeq(nuc) (6)   
   GenBank (22)   
   EMBL (22)   
Protein domain (3)   
   Pfam (3)   
All databases (230)   

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KEGG   Homo sapiens (human): 3303
Entry
3303              CDS       T01001                                 

Gene name
HSPA1A, HEL-S-103, HSP70-1, HSP70-1A, HSP70-2, HSP70.1, HSP70.2, HSP70I, HSP72, HSPA1
Definition
(RefSeq) heat shock protein family A (Hsp70) member 1A
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
hsa04010  MAPK signaling pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04144  Endocytosis
hsa04213  Longevity regulating pathway - multiple species
hsa04612  Antigen processing and presentation
hsa04915  Estrogen signaling pathway
hsa05020  Prion disease
hsa05134  Legionellosis
hsa05145  Toxoplasmosis
hsa05162  Measles
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    3303 (HSPA1A)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3303 (HSPA1A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3303 (HSPA1A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3303 (HSPA1A)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    3303 (HSPA1A)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3303 (HSPA1A)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    3303 (HSPA1A)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    3303 (HSPA1A)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    3303 (HSPA1A)
  09172 Infectious disease: viral
   05162 Measles
    3303 (HSPA1A)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3303 (HSPA1A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3303 (HSPA1A)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    3303 (HSPA1A)
   03009 Ribosome biogenesis [BR:hsa03009]
    3303 (HSPA1A)
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3303 (HSPA1A)
   04131 Membrane trafficking [BR:hsa04131]
    3303 (HSPA1A)
   03051 Proteasome [BR:hsa03051]
    3303 (HSPA1A)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3303 (HSPA1A)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3303 (HSPA1A)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3303 (HSPA1A)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    3303 (HSPA1A)
 Complex C
   Prp19-CDC5 complex
    3303 (HSPA1A)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    3303 (HSPA1A)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP70 / DNAK
   3303 (HSPA1A)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    3303 (HSPA1A)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3303 (HSPA1A)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3303 (HSPA1A)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    3303 (HSPA1A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3303 (HSPA1A)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C DDR Hydantoinase_A Radial_spoke_3
Other DBs
NCBI-GeneID: 3303
NCBI-ProteinID: NP_005336
OMIM: 140550
HGNC: 5232
Ensembl: ENSG00000204389
Vega: OTTHUMG00000031201
UniProt: P0DMV8 P0DMV9 A8K5I0 B3KTT5
Structure
PDB: 

Position
6p21.33
AA seq 641 aa
MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS
SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA
IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH
FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA
RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN
KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI
PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI
DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN
ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE
QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
NT seq 1926 nt   +upstreamnt  +downstreamnt
atggccaaagccgcggcgatcggcatcgacctgggcaccacctactcctgcgtgggggtg
ttccaacacggcaaggtggagatcatcgccaacgaccagggcaaccgcaccacccccagc
tacgtggccttcacggacaccgagcggctcatcggggatgcggccaagaaccaggtggcg
ctgaacccgcagaacaccgtgtttgacgcgaagcggctgattggccgcaagttcggcgac
ccggtggtgcagtcggacatgaagcactggcctttccaggtgatcaacgacggagacaag
cccaaggtgcaggtgagctacaagggggagaccaaggcattctaccccgaggagatctcg
tccatggtgctgaccaagatgaaggagatcgccgaggcgtacctgggctacccggtgacc
aacgcggtgatcaccgtgccggcctacttcaacgactcgcagcgccaggccaccaaggat
gcgggtgtgatcgcggggctcaacgtgctgcggatcatcaacgagcccacggccgccgcc
atcgcctacggcctggacagaacgggcaagggggagcgcaacgtgctcatctttgacctg
ggcgggggcaccttcgacgtgtccatcctgacgatcgacgacggcatcttcgaggtgaag
gccacggccggggacacccacctgggtggggaggactttgacaacaggctggtgaaccac
ttcgtggaggagttcaagagaaaacacaagaaggacatcagccagaacaagcgagccgtg
aggcggctgcgcaccgcctgcgagagggccaagaggaccctgtcgtccagcacccaggcc
agcctggagatcgactccctgtttgagggcatcgacttctacacgtccatcaccagggcg
aggttcgaggagctgtgctccgacctgttccgaagcaccctggagcccgtggagaaggct
ctgcgcgacgccaagctggacaaggcccagattcacgacctggtcctggtcgggggctcc
acccgcatccccaaggtgcagaagctgctgcaggacttcttcaacgggcgcgacctgaac
aagagcatcaaccccgacgaggctgtggcctacggggcggcggtgcaggcggccatcctg
atgggggacaagtccgagaacgtgcaggacctgctgctgctggacgtggctcccctgtcg
ctggggctggagacggccggaggcgtgatgactgccctgatcaagcgcaactccaccatc
cccaccaagcagacgcagatcttcaccacctactccgacaaccaacccggggtgctgatc
caggtgtacgagggcgagagggccatgacgaaagacaacaatctgttggggcgcttcgag
ctgagcggcatccctccggcccccaggggcgtgccccagatcgaggtgaccttcgacatc
gatgccaacggcatcctgaacgtcacggccacggacaagagcaccggcaaggccaacaag
atcaccatcaccaacgacaagggccgcctgagcaaggaggagatcgagcgcatggtgcag
gaggcggagaagtacaaagcggaggacgaggtgcagcgcgagagggtgtcagccaagaac
gccctggagtcctacgccttcaacatgaagagcgccgtggaggatgaggggctcaagggc
aagatcagcgaggcggacaagaagaaggtgctggacaagtgtcaagaggtcatctcgtgg
ctggacgccaacaccttggccgagaaggacgagtttgagcacaagaggaaggagctggag
caggtgtgtaaccccatcatcagcggactgtaccagggtgccggtggtcccgggcctggg
ggcttcggggctcagggtcccaagggagggtctgggtcaggccccaccattgaggaggta
gattag

  All links  
Ontology (9)   
   KEGG BRITE (9)   
Pathway (11)   
   KEGG PATHWAY (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (45)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (13)   
   OC (1)   
   PRONIT (4)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (4)   
   SWISS-PROT (2)   
   RefSeq(pep) (1)   
DNA sequence (41)   
   RefSeq(nuc) (1)   
   GenBank (20)   
   EMBL (20)   
Protein domain (6)   
   Pfam (6)   
All databases (121)   

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KEGG   Homo sapiens (human): 3304
Entry
3304              CDS       T01001                                 

Gene name
HSPA1B, HSP70-1, HSP70-1B, HSP70-2, HSP70.1, HSP70.2, HSP72, HSPA1, HSX70
Definition
(RefSeq) heat shock protein family A (Hsp70) member 1B
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
hsa04010  MAPK signaling pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04144  Endocytosis
hsa04213  Longevity regulating pathway - multiple species
hsa04612  Antigen processing and presentation
hsa04915  Estrogen signaling pathway
hsa05020  Prion disease
hsa05134  Legionellosis
hsa05145  Toxoplasmosis
hsa05162  Measles
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    3304 (HSPA1B)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3304 (HSPA1B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3304 (HSPA1B)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3304 (HSPA1B)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    3304 (HSPA1B)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3304 (HSPA1B)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    3304 (HSPA1B)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    3304 (HSPA1B)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    3304 (HSPA1B)
  09172 Infectious disease: viral
   05162 Measles
    3304 (HSPA1B)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3304 (HSPA1B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3304 (HSPA1B)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    3304 (HSPA1B)
   03009 Ribosome biogenesis [BR:hsa03009]
    3304 (HSPA1B)
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3304 (HSPA1B)
   04131 Membrane trafficking [BR:hsa04131]
    3304 (HSPA1B)
   03051 Proteasome [BR:hsa03051]
    3304 (HSPA1B)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3304 (HSPA1B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3304 (HSPA1B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3304 (HSPA1B)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    3304 (HSPA1B)
 Complex C
   Prp19-CDC5 complex
    3304 (HSPA1B)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    3304 (HSPA1B)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP70 / DNAK
   3304 (HSPA1B)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    3304 (HSPA1B)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3304 (HSPA1B)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3304 (HSPA1B)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    3304 (HSPA1B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3304 (HSPA1B)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C DDR Hydantoinase_A Radial_spoke_3
Other DBs
NCBI-GeneID: 3304
NCBI-ProteinID: NP_005337
OMIM: 603012
HGNC: 5233
Ensembl: ENSG00000204388
Vega: OTTHUMG00000031202
Pharos: P0DMV8(Tchem) P0DMV9(Tbio)
UniProt: P0DMV8 P0DMV9 A8K5I0
Structure
PDB: 

Position
6p21.33
AA seq 641 aa
MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS
SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA
IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH
FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA
RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN
KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI
PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI
DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN
ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE
QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
NT seq 1926 nt   +upstreamnt  +downstreamnt
atggccaaagccgcggcgatcggcatcgacctgggcaccacctactcctgcgtgggggtg
ttccaacacggcaaggtggagatcatcgccaacgaccagggcaaccgcaccacccccagc
tacgtggccttcacggacaccgagcggctcatcggggatgcggccaagaaccaggtggcg
ctgaacccgcagaacaccgtgtttgacgcgaagcggctgattggccgcaagttcggcgac
ccggtggtgcagtcggacatgaagcactggcctttccaggtgatcaacgacggagacaag
cccaaggtgcaggtgagctacaagggggagaccaaggcattctaccccgaggagatctcg
tccatggtgctgaccaagatgaaggagatcgccgaggcgtacctgggctacccggtgacc
aacgcggtgatcaccgtgccggcctacttcaacgactcgcagcgccaggccaccaaggat
gcgggtgtgatcgcggggctcaacgtgctgcggatcatcaacgagcccacggccgccgcc
atcgcctacggcctggacagaacgggcaagggggagcgcaacgtgctcatctttgacctg
ggcgggggcaccttcgacgtgtccatcctgacgatcgacgacggcatcttcgaggtgaag
gccacggccggggacacccacctgggtggggaggactttgacaacaggctggtgaaccac
ttcgtggaggagttcaagagaaaacacaagaaggacatcagccagaacaagcgagccgtg
aggcggctgcgcaccgcctgcgagagggccaagaggaccctgtcgtccagcacccaggcc
agcctggagatcgactccctgtttgagggcatcgacttctacacgtccatcaccagggcg
aggttcgaggagctgtgctccgacctgttccgaagcaccctggagcccgtggagaaggct
ctgcgcgacgccaagctggacaaggcccagattcacgacctggtcctggtcgggggctcc
acccgcatccccaaggtgcagaagctgctgcaggacttcttcaacgggcgcgacctgaac
aagagcatcaaccccgacgaggctgtggcctacggggcggcggtgcaggcggccatcctg
atgggggacaagtccgagaacgtgcaggacctgctgctgctggacgtggctcccctgtcg
ctggggctggagacggccggaggcgtgatgactgccctgatcaagcgcaactccaccatc
cccaccaagcagacgcagatcttcaccacctactccgacaaccaacccggggtgctgatc
caggtgtacgagggcgagagggccatgacgaaagacaacaatctgttggggcgcttcgag
ctgagcggcatccctccggcccccaggggcgtgccccagatcgaggtgaccttcgacatc
gatgccaacggcatcctgaacgtcacggccacggacaagagcaccggcaaggccaacaag
atcaccatcaccaacgacaagggccgcctgagcaaggaggagatcgagcgcatggtgcag
gaggcggagaagtacaaagcggaggacgaggtgcagcgcgagagggtgtcagccaagaac
gccctggagtcctacgccttcaacatgaagagcgccgtggaggatgaggggctcaagggc
aagatcagcgaggcggacaagaagaaggttctggacaagtgtcaagaggtcatctcgtgg
ctggacgccaacaccttggccgagaaggacgagtttgagcacaagaggaaggagctggag
caggtgtgtaaccccatcatcagcggactgtaccagggtgccggtggtcccgggcctggc
ggcttcggggctcagggtcccaagggagggtctgggtcaggccctaccattgaggaggtg
gattag

  All links  
Ontology (9)   
   KEGG BRITE (9)   
Pathway (11)   
   KEGG PATHWAY (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PHAROS (2)   
   PRONIT (4)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (3)   
   SWISS-PROT (2)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (6)   
   Pfam (6)   
All databases (89)   

Download RDF
KEGG   Homo sapiens (human): 3305
Entry
3305              CDS       T01001                                 

Gene name
HSPA1L, HSP70-1L, HSP70-HOM, HSP70T, hum70t
Definition
(RefSeq) heat shock protein family A (Hsp70) member 1 like
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
hsa04010  MAPK signaling pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04144  Endocytosis
hsa04213  Longevity regulating pathway - multiple species
hsa04612  Antigen processing and presentation
hsa04915  Estrogen signaling pathway
hsa05020  Prion disease
hsa05134  Legionellosis
hsa05145  Toxoplasmosis
hsa05162  Measles
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    3305 (HSPA1L)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3305 (HSPA1L)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3305 (HSPA1L)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3305 (HSPA1L)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    3305 (HSPA1L)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3305 (HSPA1L)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    3305 (HSPA1L)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    3305 (HSPA1L)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    3305 (HSPA1L)
  09172 Infectious disease: viral
   05162 Measles
    3305 (HSPA1L)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3305 (HSPA1L)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3305 (HSPA1L)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    3305 (HSPA1L)
   03009 Ribosome biogenesis [BR:hsa03009]
    3305 (HSPA1L)
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3305 (HSPA1L)
   04131 Membrane trafficking [BR:hsa04131]
    3305 (HSPA1L)
   03051 Proteasome [BR:hsa03051]
    3305 (HSPA1L)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3305 (HSPA1L)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3305 (HSPA1L)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3305 (HSPA1L)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    3305 (HSPA1L)
 Complex C
   Prp19-CDC5 complex
    3305 (HSPA1L)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    3305 (HSPA1L)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP70 / DNAK
   3305 (HSPA1L)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    3305 (HSPA1L)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3305 (HSPA1L)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3305 (HSPA1L)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    3305 (HSPA1L)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3305 (HSPA1L)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C Radial_spoke_3
Other DBs
NCBI-GeneID: 3305
NCBI-ProteinID: NP_005518
OMIM: 140559
HGNC: 5234
Ensembl: ENSG00000204390
Vega: OTTHUMG00000031208
Pharos: P34931(Tbio)
UniProt: P34931 A0A1U9X7W7
Structure
PDB: 
3GDQ

Position
6p21.33
AA seq 641 aa
MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ
VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE
ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA
AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV
SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT
RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD
LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS
TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF
DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA
KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE
LEQMCNPIITKLYQGGCTGPACGTGYVPGRPATGPTIEEVD
NT seq 1926 nt   +upstreamnt  +downstreamnt
atggctactgccaagggaatcgccataggcatcgacctgggcaccacctactcctgtgtg
ggggtgttccagcacggcaaggtggagatcatcgccaacgaccagggcaaccgcaccacc
cccagctacgtggccttcacagacaccgagcggctcattggggatgcggccaagaaccag
gtagcaatgaatccccagaacactgtttttgatgctaaacgtctgatcggcaggaaattt
aatgatcctgttgtacaagcagatatgaaactttggccttttcaagtgattaatgaagga
ggcaagcccaaagtccttgtgtcctacaaaggggagaataaagctttctaccctgaggaa
atctcttcgatggtattgactaagttgaaggagactgctgaggcctttttgggccaccct
gtcaccaatgcagtgattaccgtgccagcctatttcaatgactctcaacgtcaggctact
aaggatgcaggtgtgattgctggacttaatgtgctaagaatcatcaatgagcccacggct
gctgccattgcctatggtttagataaaggaggtcaaggagaacgacatgtcctgattttt
gatctgggtggaggcacatttgatgtgtcaattctgaccatagatgatgggatttttgag
gtaaaggccactgctggggacactcacctgggtggggaggactttgacaacaggcttgtg
agccacttcgtggaggagttcaagaggaaacacaaaaaggacatcagccagaacaagcga
gccgtgaggcggctgcgcaccgcctgcgagagggccaagaggaccctgtcgtccagcacc
caggccaacctagaaattgattcactttatgaaggcattgacttctatacatccatcacc
agagctcgatttgaagagttgtgtgcagacctgtttaggggtaccctggagcctgtagaa
aaagcgcttcgggatgccaagatggataaggctaaaatccatgacattgttttagtaggg
ggctccacccgcatccccaaggtgcagcggctgcttcaggactacttcaatggacgtgat
ctcaacaagagcatcaaccctgatgaggccgtagcatatggggctgcggtacaagcagcc
atcctgatgggggacaagtctgagaaggtacaggacctgctgctgctggacgtggctccc
ctgtccctggggctggagacggctgggggcgtgatgactgccctgataaagcgcaactcc
accatccccaccaagcagacacagattttcaccacctactctgacaaccaacccggggtg
ctgatccaggtgtatgagggcgagagggccatgacaaaggacaacaacctgctggggcgg
tttgacctgactggaatccctccagcacccaggggagttcctcagatcgaggtgacgttt
gacattgatgccaatggtattctcaatgtcacagccacggacaagagcaccggcaaggtg
aacaagatcaccatcaccaatgacaagggccgcctgagcaaggaggagattgagcgcatg
gttctggatgctgagaaatataaagctgaagatgaggtccagagggagaaaattgctgca
aagaatgccttagaatcctatgcttttaacatgaagagtgttgtgagtgatgaaggtttg
aagggcaagattagtgagtctgataaaaataaaatattggataaatgcaacgagctcctt
tcgtggctggaggtcaatcaactggcagagaaagatgagtttgatcataagagaaaggaa
ttggagcagatgtgtaaccctatcatcacaaaactctaccaaggaggatgcactgggcct
gcctgcggaacagggtatgtgcctggaaggcctgccacaggccccacaattgaagaagta
gattaa

  All links  
Ontology (9)   
   KEGG BRITE (9)   
Pathway (11)   
   KEGG PATHWAY (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (4)   
   Pfam (4)   
All databases (78)   

Download RDF
KEGG   Homo sapiens (human): 3306
Entry
3306              CDS       T01001                                 

Gene name
HSPA2, HSP70-2, HSP70-3
Definition
(RefSeq) heat shock protein family A (Hsp70) member 2
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
hsa04010  MAPK signaling pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04144  Endocytosis
hsa04213  Longevity regulating pathway - multiple species
hsa04612  Antigen processing and presentation
hsa04915  Estrogen signaling pathway
hsa05020  Prion disease
hsa05134  Legionellosis
hsa05145  Toxoplasmosis
hsa05162  Measles
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    3306 (HSPA2)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3306 (HSPA2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3306 (HSPA2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3306 (HSPA2)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    3306 (HSPA2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3306 (HSPA2)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    3306 (HSPA2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    3306 (HSPA2)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    3306 (HSPA2)
  09172 Infectious disease: viral
   05162 Measles
    3306 (HSPA2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3306 (HSPA2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3306 (HSPA2)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    3306 (HSPA2)
   03009 Ribosome biogenesis [BR:hsa03009]
    3306 (HSPA2)
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3306 (HSPA2)
   04131 Membrane trafficking [BR:hsa04131]
    3306 (HSPA2)
   03051 Proteasome [BR:hsa03051]
    3306 (HSPA2)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3306 (HSPA2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3306 (HSPA2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3306 (HSPA2)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    3306 (HSPA2)
 Complex C
   Prp19-CDC5 complex
    3306 (HSPA2)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    3306 (HSPA2)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP70 / DNAK
   3306 (HSPA2)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    3306 (HSPA2)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3306 (HSPA2)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3306 (HSPA2)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    3306 (HSPA2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3306 (HSPA2)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C Hydantoinase_A DUF1464 DDR CRIC_ras_sig
Other DBs
NCBI-GeneID: 3306
NCBI-ProteinID: NP_068814
OMIM: 140560
HGNC: 5235
Ensembl: ENSG00000126803
Vega: OTTHUMG00000141311
Pharos: P54652(Tbio)
UniProt: P54652 A0A024R6B5
Structure
PDB: 

Position
14q23.3
AA seq 639 aa
MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV
AMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEI
SSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAA
AIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM
VSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSI
TRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGK
ELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRN
TTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVT
FDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVA
AKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQK
ELERVCNPIISKLYQGGPGGGSGGGGSGASGGPTIEEVD
NT seq 1920 nt   +upstreamnt  +downstreamnt
atgtctgcccgtggcccggctatcggcatcgacctgggcaccacctattcgtgcgtcggg
gtcttccaacatggcaaggtggagatcatcgccaacgaccagggcaatcgcaccaccccc
agctacgtggccttcacggacaccgagcgcctcatcggcgacgccgccaagaaccaggtg
gccatgaaccccaccaacaccatcttcgacgccaagaggctgattggacggaaattcgag
gatgccacagtgcagtcggatatgaaacactggccgttccgggtggtgagcgagggaggc
aagcccaaagtgcaagtagagtacaagggggagaccaagaccttcttcccagaggagata
tcctccatggtcctcacgaagatgaaggagatcgcggaagcctacctggggggcaaggtg
cacagcgcggtcataacggtcccggcctatttcaacgactcgcagcgccaggccaccaag
gacgcaggcaccatcacggggctcaatgtgctgcgcatcatcaacgagcccacggcggcg
gccatcgcctacggcctggacaagaagggctgcgcgggcggcgagaagaacgtgctcatc
tttgacctgggcggtggcactttcgacgtgtccatcctgaccatcgaggatggcatcttc
gaggtgaagtccacggccggcgacacccacctgggcggtgaggacttcgacaaccgcatg
gtgagccacctggcggaggagttcaagcgcaagcacaagaaggacattgggcccaacaag
cgcgccgtgaggcggctgcgcaccgcttgcgagcgcgccaagcgcaccctgagctcgtcc
acgcaggcgagcatcgagatcgactcgctctacgagggcgtggacttctatacgtccatc
acgcgcgcccgcttcgaggagctcaatgccgacctctttcgcgggaccctggagccggtg
gagaaggcgctgcgcgacgccaagctggacaagggccagatccaggagatcgtgctggtg
ggcggctccactcgtatccccaagatccagaagctgctgcaggatttcttcaacggcaag
gagctgaacaagagcatcaaccccgacgaggcggtggcctatggcgccgcggtgcaggcg
gccatcctcatcggcgacaaatcagagaatgtgcaggacctgctgctactcgacgtgacc
ccgttgtcgctgggcatcgagacagctggcggtgtcatgaccccactcatcaagaggaac
accacgatccccaccaagcagacgcagaccttcaccacctactcggacaaccagagcagc
gtactggtgcaggtatacgagggcgaacgggccatgaccaaggacaataacctgctgggc
aagttcgacctgaccgggattccccctgcgcctcgcggggtcccccaaatcgaggttacc
ttcgacattgacgccaatggcatccttaacgttaccgccgccgacaagagcaccggtaag
gaaaacaaaatcaccatcaccaatgacaaaggtcgtctgagcaaggacgacattgaccgg
atggtgcaggaggcggagcggtacaaatcggaagatgaggcgaatcgcgaccgagtcgcg
gccaaaaacgccctggagtcctatacctacaacatcaagcagacggtggaagacgagaaa
ctgaggggcaagattagcgagcaggacaaaaacaagatcctcgacaagtgtcaggaggtg
atcaactggctcgaccgaaaccagatggcagagaaagatgagtatgaacacaagcagaaa
gagctcgaaagagtttgcaaccccatcatcagcaaactttaccaaggtggtcctggcggc
ggcagcggcggcggcggttcaggagcctccgggggacccaccatcgaagaagtggactaa

  All links  
Ontology (9)   
   KEGG BRITE (9)   
Pathway (11)   
   KEGG PATHWAY (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (106)   
   KEGG ORTHOLOGY (1)   
   RefGene (96)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
Protein domain (7)   
   Pfam (7)   
All databases (164)   

Download RDF
KEGG   Homo sapiens (human): 3310
Entry
3310              CDS       T01001                                 

Gene name
HSPA6, HSP70B'
Definition
(RefSeq) heat shock protein family A (Hsp70) member 6
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
hsa04010  MAPK signaling pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04144  Endocytosis
hsa04213  Longevity regulating pathway - multiple species
hsa04612  Antigen processing and presentation
hsa04915  Estrogen signaling pathway
hsa05020  Prion disease
hsa05134  Legionellosis
hsa05145  Toxoplasmosis
hsa05162  Measles
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    3310 (HSPA6)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3310 (HSPA6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3310 (HSPA6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3310 (HSPA6)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    3310 (HSPA6)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3310 (HSPA6)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    3310 (HSPA6)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    3310 (HSPA6)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    3310 (HSPA6)
  09172 Infectious disease: viral
   05162 Measles
    3310 (HSPA6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3310 (HSPA6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3310 (HSPA6)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    3310 (HSPA6)
   03009 Ribosome biogenesis [BR:hsa03009]
    3310 (HSPA6)
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3310 (HSPA6)
   04131 Membrane trafficking [BR:hsa04131]
    3310 (HSPA6)
   03051 Proteasome [BR:hsa03051]
    3310 (HSPA6)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3310 (HSPA6)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3310 (HSPA6)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3310 (HSPA6)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    3310 (HSPA6)
 Complex C
   Prp19-CDC5 complex
    3310 (HSPA6)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    3310 (HSPA6)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP70 / DNAK
   3310 (HSPA6)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    3310 (HSPA6)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3310 (HSPA6)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3310 (HSPA6)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    3310 (HSPA6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3310 (HSPA6)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C Hydantoinase_A DUF1464
Other DBs
NCBI-GeneID: 3310
NCBI-ProteinID: NP_002146
OMIM: 140555
HGNC: 5239
Ensembl: ENSG00000173110
Vega: OTTHUMG00000034461
Pharos: P17066(Tbio)
UniProt: P17066 B3KSM6 A0A384NKX5
Structure
PDB: 
3FE1

Position
1q23.3
AA seq 643 aa
MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQ
AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEE
ISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTA
AAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLV
NHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSIT
RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKE
LNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNA
TIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF
DIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAA
KNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE
LEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD
NT seq 1932 nt   +upstreamnt  +downstreamnt
atgcaggccccacgggagctcgcggtgggcatcgacctgggcaccacctactcgtgcgtg
ggcgtgtttcagcagggccgcgtggagatcctggccaacgaccagggcaaccgcaccacg
cccagctacgtggccttcaccgacaccgagcggctggtcggggacgcggccaagagccag
gcggccctgaacccccacaacaccgtgttcgatgccaagcggctgatcgggcgcaagttc
gcggacaccacggtgcagtcggacatgaagcactggcccttccgggtggtgagcgagggc
ggcaagcccaaggtgcgcgtatgctaccgcggggaggacaagacgttctaccccgaggag
atctcgtccatggtgctgagcaagatgaaggagacggccgaggcgtacctgggccagccc
gtgaagcacgcagtgatcaccgtgcccgcctatttcaatgactcgcagcgccaggccacc
aaggacgcgggggccatcgcggggctcaacgtgttgcggatcatcaatgagcccacggca
gctgccatcgcctatgggctggaccggcggggcgcgggagagcgcaacgtgctcattttt
gacctgggtgggggcaccttcgatgtgtcggttctctccattgacgctggtgtctttgag
gtgaaagccactgctggagatacccacctgggaggagaggacttcgacaaccggctcgtg
aaccacttcatggaagaattccggcggaagcatgggaaggacctgagcgggaacaagcgt
gccctgcgcaggctgcgcacagcctgtgagcgcgccaagcgcaccctgtcctccagcacc
caggccaccctggagatagactccctgttcgagggcgtggacttctacacgtccatcact
cgtgcccgctttgaggaactgtgctcagacctcttccgcagcaccctggagccggtggag
aaggccctgcgggatgccaagctggacaaggcccagattcatgacgtcgtcctggtgggg
ggctccacacgcatccccaaggtgcagaagttgctgcaggacttcttcaacggcaaggag
ctgaacaagagcatcaaccctgatgaggctgtggcctatggggctgctgtgcaggcggcc
gtgttgatgggggacaaatgtgagaaagtgcaggatctcctgctgctggatgtggctccc
ctgtctctggggctggagacagcaggtggggtgatgaccacgctgatccagaggaacgcc
actatccccaccaagcagacccagactttcaccacctactcggacaaccagcctggggtc
ttcatccaggtgtatgagggtgagagggccatgaccaaggacaacaacctgctggggcgt
tttgaactcagtggcatccctcctgccccacgtggagtcccccagatagaggtgactttt
gacattgatgctaatggcatcctgagcgtgacagccactgacaggagcacaggtaaggct
aacaagatcaccatcaccaatgacaagggccggctgagcaaggaggaggtggagaggatg
gttcatgaagccgagcagtacaaggctgaggatgaggcccagagggacagagtggctgcc
aaaaactcgctggaggcccatgtcttccatgtgaaaggttctttgcaagaggaaagcctt
agggacaagattcccgaagaggacaggcgcaaaatgcaagacaagtgtcgggaagtcctt
gcctggctggagcacaaccagctggcagagaaggaggagtatgagcatcagaagagggag
ctggagcaaatctgtcgccccatcttctccaggctctatggggggcctggtgtccctggg
ggcagcagttgtggcactcaagcccgccagggggaccccagcaccggccccatcattgag
gaggttgattga

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Ontology (9)   
   KEGG BRITE (9)   
Pathway (11)   
   KEGG PATHWAY (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (44)   
   KEGG ORTHOLOGY (1)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
Protein domain (5)   
   Pfam (5)   
All databases (99)   

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KEGG   Homo sapiens (human): 3312
Entry
3312              CDS       T01001                                 

Gene name
HSPA8, HEL-33, HEL-S-72p, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP-1, LAP1, NIP71
Definition
(RefSeq) heat shock protein family A (Hsp70) member 8
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
hsa04010  MAPK signaling pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04144  Endocytosis
hsa04213  Longevity regulating pathway - multiple species
hsa04612  Antigen processing and presentation
hsa04915  Estrogen signaling pathway
hsa05020  Prion disease
hsa05134  Legionellosis
hsa05145  Toxoplasmosis
hsa05162  Measles
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    3312 (HSPA8)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3312 (HSPA8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3312 (HSPA8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3312 (HSPA8)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    3312 (HSPA8)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3312 (HSPA8)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    3312 (HSPA8)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    3312 (HSPA8)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    3312 (HSPA8)
  09172 Infectious disease: viral
   05162 Measles
    3312 (HSPA8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3312 (HSPA8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3312 (HSPA8)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    3312 (HSPA8)
   03009 Ribosome biogenesis [BR:hsa03009]
    3312 (HSPA8)
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3312 (HSPA8)
   04131 Membrane trafficking [BR:hsa04131]
    3312 (HSPA8)
   03051 Proteasome [BR:hsa03051]
    3312 (HSPA8)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3312 (HSPA8)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3312 (HSPA8)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3312 (HSPA8)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    3312 (HSPA8)
 Complex C
   Prp19-CDC5 complex
    3312 (HSPA8)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    3312 (HSPA8)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP70 / DNAK
   3312 (HSPA8)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    3312 (HSPA8)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3312 (HSPA8)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3312 (HSPA8)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    3312 (HSPA8)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3312 (HSPA8)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C DDR HORMA MetOD2
Other DBs
NCBI-GeneID: 3312
NCBI-ProteinID: NP_006588
OMIM: 600816
HGNC: 5241
Ensembl: ENSG00000109971
Vega: OTTHUMG00000166030
Pharos: P11142(Tchem)
UniProt: P11142 V9HW22 Q53HF2
Structure
PDB: 

Position
11q24.1
AA seq 646 aa
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI
DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN
SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE
KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
NT seq 1941 nt   +upstreamnt  +downstreamnt
atgtccaagggacctgcagttggtattgatcttggcaccacctactcttgtgtgggtgtt
ttccagcacggaaaagtcgagataattgccaatgatcagggaaaccgaaccactccaagc
tatgtcgcctttacggacactgaacggttgatcggtgatgccgcaaagaatcaagttgca
atgaaccccaccaacacagtttttgatgccaaacgtctgattggacgcagatttgatgat
gctgttgtccagtctgatatgaaacattggccctttatggtggtgaatgatgctggcagg
cccaaggtccaagtagaatacaagggagagaccaaaagcttctatccagaggaggtgtct
tctatggttctgacaaagatgaaggaaattgcagaagcctaccttgggaagactgttacc
aatgctgtggtcacagtgccagcttactttaatgactctcagcgtcaggctaccaaagat
gctggaactattgctggtctcaatgtacttagaattattaatgagccaactgctgctgct
attgcttacggcttagacaaaaaggttggagcagaaagaaacgtgctcatctttgacctg
ggaggtggcacttttgatgtgtcaatcctcactattgaggatggaatctttgaggtcaag
tctacagctggagacacccacttgggtggagaagattttgacaaccgaatggtcaaccat
tttattgctgagtttaagcgcaagcataagaaggacatcagtgagaacaagagagctgta
agacgcctccgtactgcttgtgaacgtgctaagcgtaccctctcttccagcacccaggcc
agtattgagatcgattctctctatgaaggaatcgacttctatacctccattacccgtgcc
cgatttgaagaactgaatgctgacctgttccgtggcaccctggacccagtagagaaagcc
cttcgagatgccaaactagacaagtcacagattcatgatattgtcctggttggtggttct
actcgtatccccaagattcagaagcttctccaagacttcttcaatggaaaagaactgaat
aagagcatcaaccctgatgaagctgttgcttatggtgcagctgtccaggcagccatcttg
tctggagacaagtctgagaatgttcaagatttgctgctcttggatgtcactcctctttcc
cttggtattgaaactgctggtggagtcatgactgtcctcatcaagcgtaataccaccatt
cctaccaagcagacacagaccttcactacctattctgacaaccagcctggtgtgcttatt
caggtttatgaaggcgagcgtgccatgacaaaggataacaacctgcttggcaagtttgaa
ctcacaggcatacctcctgcaccccgaggtgttcctcagattgaagtcacttttgacatt
gatgccaatggtatactcaatgtctctgctgtggacaagagtacgggaaaagagaacaag
attactatcactaatgacaagggccgtttgagcaaggaagacattgaacgtatggtccag
gaagctgagaagtacaaagctgaagatgagaagcagagggacaaggtgtcatccaagaat
tcacttgagtcctatgccttcaacatgaaagcaactgttgaagatgagaaacttcaaggc
aagattaacgatgaggacaaacagaagattctggacaagtgtaatgaaattatcaactgg
cttgataagaatcagactgctgagaaggaagaatttgaacatcaacagaaagagctggag
aaagtttgcaaccccatcatcaccaagctgtaccagagtgcaggaggcatgccaggagga
atgcctgggggatttcctggtggtggagctcctccctctggtggtgcttcctcagggccc
accattgaagaggttgattaa

  All links  
Ontology (9)   
   KEGG BRITE (9)   
Pathway (11)   
   KEGG PATHWAY (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (169)   
   KEGG ORTHOLOGY (1)   
   RefGene (84)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (77)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (55)   
   RefSeq(nuc) (3)   
   GenBank (26)   
   EMBL (26)   
Protein domain (6)   
   Pfam (6)   
All databases (259)   

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