KEGG   Homo sapiens (human): 145957
Entry
145957            CDS       T01001                                 
Symbol
NRG4, HRG4
Name
(RefSeq) neuregulin 4
  KO
K05458  neuregulin 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04012  ErbB signaling pathway
hsa05014  Amyotrophic lateral sclerosis
Network
nt06464  Amyotrophic lateral sclerosis
nt06530  PI3K signaling
nt06543  NRG-ERBB signaling
  Element
N01163  NRG-ERBB4-PI3K signaling pathway
N01164  Mutation-inactivated ERBB4 to NRG-ERBB4-PI3K signaling pathway
N01656  GF-RTK-PI3K signaling pathway
N01658  GF-RTK-RAS-PI3K signaling pathway
N01877  ERBB4 mutation to GF-RTK-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    145957 (NRG4)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    145957 (NRG4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    145957 (NRG4)
Cytokines and neuropeptides [BR:hsa04052]
 Cytokines
  Growth factors (RTK binding)
   145957 (NRG4)
SSDB
Motif
Pfam: EGF EGF_Teneurin EGF_LRP2 EGF_2
Other DBs
NCBI-GeneID: 145957
NCBI-ProteinID: NP_612640
OMIM: 610894
HGNC: 29862
Ensembl: ENSG00000169752
UniProt: Q8WWG1
Position
15:complement(75935393..76060240)
AA seq 115 aa
MPTDHEEPCGPSHKSFCLNGGLCYVIPTIPSPFCRCVENYTGARCEEVFLPGSSIQTKSN
LFEAFVALAVLVTLIIGAFYFLCRKGHFQRASSVQYDINLVETSSTSAHHSHEQH
NT seq 348 nt   +upstreamnt  +downstreamnt
atgccaacagatcacgaagagccctgtggtcccagtcacaagtcgttttgcctgaatggg
gggctttgttatgtgatacctactattcccagcccattttgtaggtgcgttgaaaactat
acaggagctcgttgtgaagaggtttttctcccaggctccagcatccaaactaaaagtaac
ctgtttgaagcttttgtggcattggcggtcctagtaacacttatcattggagccttctac
ttcctttgcaggaaaggccactttcagagagccagttcagtccagtatgatatcaacctg
gtagagacgagcagtaccagtgcccaccacagtcatgaacaacactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (8)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (25)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (23)   
DNA sequence (45)   
   RefSeq(nuc) (27)   
   GenBank (9)   
   EMBL (9)   
Protein domain (4)   
   Pfam (4)   
All databases (83)   

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