KEGG   Homo sapiens (human): 146Help
Entry
146               CDS       T01001                                 

Gene name
ADRA1D, ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2
Definition
(RefSeq) adrenoceptor alpha 1D
  KO
K04137  adrenergic receptor alpha-1D
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion
Drug target
Adrenalone (DG00016): D02774 D07560
Amidephrine mesylate: D02901
Amiodarone (DG00204): D00636 D02910
Amosulalol (DG01302): D01469 D07451
Arotinolol (DG01303): D01830 D07465
Bevantolol: D01369
Bunazosin (DG01316): D01887 D07550
Bunitrolol hydrochloride: D01444
Carvedilol (DG00321): D00255 D03415
Dapiprazole (DG01140): D03648 D07775
Dihydroergocristine (DG00284): D07833 D07834
Dipivefrine (DG01129): D01017 D02349
Domazoline fumarate: D03887
Doxazosin (DG00256): D00608 D07874
Dronedarone (DG00207): D02537 D03914
Droperidol: D00308
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Ergoloid mesylates: D02268
Ergometrine (DG00446): D01163 D07905
Ergot alkaloids: D07906
Ergotamine (DG00834): D00679
Etilefrine (DG00210): D01573 D07931
Flesinoxan: D02568
Guanadrel: D08029
Guanadrel sulfate: D00607
Ifenprodil (DG00292): D01445 D08064
Indoramin (DG00254): D04531 D04532
Labetalol (DG00320): D00600 D08106
Levobunolol (DG01136): D01025 D08115
Metaraminol (DG00218): D01019 D08192
Methoxamine (DG00219): D01020 D08201
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Methylergometrine (DG00445): D00680 D08207
Midodrine (DG00224): D01307 D08220
Monatepil maleate: D01171
Moxisylyte (DG00287): D01571 D08239
Naftopidil: D01674
Naphazoline (DG01032): D00743 D01021 D08253
Nefazodone (DG00953): D00819 D08257
Nicergoline (DG00283): D01290 D08271
Nipradilol: D01691
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Olanzapine (DG00898): D00454 D06623
Pelanserin hydrochloride: D05395
Periciazine: D01485
Phenoxybenzamine (DG00285): D00507 D08358
Phentolamine (DG00280): D00509 D08362
Phenylephrine (DG00215): D00511 D08365 D08366 D08966
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Prazosin (DG00253): D00609 D08411
Propylhexedrine (DG01919): D05637 D08444
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Tamsulosin (DG00490): D01024 D08560
Terazosin (DG00491): D00610 D08569 D11585
Tetryzoline (DG01030): D00756 D01023 D08578
Tolazoline (DG00281): D00997 D08614
Tramazoline (DG01033): D01347 D08624
Trimazosin (DG00255): D06234 D08212
Urapidil (DG00257): D01333 D08662
Xylometazoline (DG01031): D00757 D08684
Zolertine hydrochloride: D06380
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    146 (ADRA1D)
   04022 cGMP-PKG signaling pathway
    146 (ADRA1D)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    146 (ADRA1D)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    146 (ADRA1D)
   04270 Vascular smooth muscle contraction
    146 (ADRA1D)
  09154 Digestive system
   04970 Salivary secretion
    146 (ADRA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    146 (ADRA1D)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    146 (ADRA1D)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4 7TM_GPCR_Srv
Motif
Other DBs
NCBI-GeneID: 146
NCBI-ProteinID: NP_000669
OMIM: 104219
HGNC: 280
Ensembl: ENSG00000171873
Vega: OTTHUMG00000031779
Pharos: P25100(Tclin)
UniProt: P25100 B0ZBE0
Position
20p13
AA seq 572 aa AA seqDB search
MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
NT seq 1719 nt NT seq  +upstreamnt  +downstreamnt
atgactttccgcgatctcctgagcgtcagtttcgagggaccccgcccggacagcagcgca
gggggctccagcgcgggcggcggcgggggcagcgcgggcggcgcggccccctcggagggc
ccggcggtgggcggcgtgccggggggcgcgggcggcggcggcggcgtggtgggcgcaggc
agcggcgaggacaaccggagctccgcgggggagccggggagcgcgggcgcgggcggcgac
gtgaatggcacggcggccgtcgggggactggtggtgagcgcgcagggcgtgggcgtgggc
gtcttcctggcagccttcatccttatggccgtggcaggtaacctgcttgtcatcctctca
gtggcctgcaaccgccacctgcagaccgtcaccaactatttcatcgtgaacctggccgtg
gccgacctgctgctgagcgccaccgtactgcccttctcggccaccatggaggttctgggc
ttctgggcctttggccgcgccttctgcgacgtatgggccgccgtggacgtgctgtgctgc
acggcctccatcctcagcctctgcaccatctccgtggaccggtacgtgggcgtgcgccac
tcactcaagtacccagccatcatgaccgagcgcaaggcggccgccatcctggccctgctc
tgggtcgtagccctggtggtgtccgtagggcccctgctgggctggaaggagcccgtgccc
cctgacgagcgcttctgcggtatcaccgaggaggcgggctacgctgtcttctcctccgtg
tgctccttctacctgcccatggcggtcatcgtggtcatgtactgccgcgtgtacgtggtc
gcgcgcagcaccacgcgcagcctcgaggcgggcgtcaagcgcgagcgaggcaaggcctcc
gaggtggtgctgcgcatccactgtcgcggcgcggccacgggcgccgacggggcgcacggc
atgcgcagcgccaagggccacaccttccgcagctcgctctccgtgcgcctgctcaagttc
tcccgtgagaagaaagcggccaagactctggccatcgtcgtgggtgtcttcgtgctctgc
tggttccctttcttctttgtcctgccgctcggctccttgttcccgcagctgaagccatcg
gagggcgtcttcaaggtcatcttctggctcggctacttcaacagctgcgtgaacccgctc
atctacccctgttccagccgcgagttcaagcgcgccttcctccgtctcctgcgctgccag
tgccgtcgtcgccggcgccgccgccctctctggcgtgtctacggccaccactggcgggcc
tccaccagcggcctgcgccaggactgcgccccgagttcgggcgacgcgccccccggagcg
ccgctggccctcaccgcgctccccgaccccgaccccgaacccccaggcacgcccgagatg
caggctccggtcgccagccgtcgaaagccacccagcgccttccgcgagtggaggctgctg
gggccgttccggagacccacgacccagctgcgcgccaaagtctccagcctgtcgcacaag
atccgcgccgggggcgcgcagcgcgcagaggcagcgtgcgcccagcgctcagaggtggag
gctgtgtccctaggcgtcccacacgaggtggccgagggcgccacctgccaggcctacgaa
ttggccgactacagcaacctacgggagaccgatatttaa

KEGG   Homo sapiens (human): 147Help
Entry
147               CDS       T01001                                 

Gene name
ADRA1B, ADRA1, ALPHA1BAR
Definition
(RefSeq) adrenoceptor alpha 1B
  KO
K04136  adrenergic receptor alpha-1B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion
Drug target
Adrenalone (DG00016): D02774 D07560
Amidephrine mesylate: D02901
Amiodarone (DG00204): D00636 D02910
Amosulalol (DG01302): D01469 D07451
Arotinolol (DG01303): D01830 D07465
Bevantolol: D01369
Bunazosin (DG01316): D01887 D07550
Bunitrolol hydrochloride: D01444
Carvedilol (DG00321): D00255 D03415
Dapiprazole (DG01140): D03648 D07775
Dihydroergocristine (DG00284): D07833 D07834
Dipivefrine (DG01129): D01017 D02349
Domazoline fumarate: D03887
Doxazosin (DG00256): D00608 D07874
Dronedarone (DG00207): D02537 D03914
Droperidol: D00308
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Ergoloid mesylates: D02268
Ergometrine (DG00446): D01163 D07905
Ergot alkaloids: D07906
Ergotamine (DG00834): D00679
Etilefrine (DG00210): D01573 D07931
Flesinoxan: D02568
Guanadrel: D08029
Guanadrel sulfate: D00607
Ifenprodil (DG00292): D01445 D08064
Indoramin (DG00254): D04531 D04532
Labetalol (DG00320): D00600 D08106
Levobunolol (DG01136): D01025 D08115
Metaraminol (DG00218): D01019 D08192
Methoxamine (DG00219): D01020 D08201
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Methylergometrine (DG00445): D00680 D08207
Midodrine (DG00224): D01307 D08220
Monatepil maleate: D01171
Moxisylyte (DG00287): D01571 D08239
Naftopidil: D01674
Naphazoline (DG01032): D00743 D01021 D08253
Nefazodone (DG00953): D00819 D08257
Nicergoline (DG00283): D01290 D08271
Nipradilol: D01691
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Olanzapine (DG00898): D00454 D06623
Pelanserin hydrochloride: D05395
Periciazine: D01485
Phenoxybenzamine (DG00285): D00507 D08358
Phentolamine (DG00280): D00509 D08362
Phenylephrine (DG00215): D00511 D08365 D08366 D08966
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Prazosin (DG00253): D00609 D08411
Propylhexedrine (DG01919): D05637 D08444
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Tamsulosin (DG00490): D01024 D08560
Terazosin (DG00491): D00610 D08569 D11585
Tetryzoline (DG01030): D00756 D01023 D08578
Tolazoline (DG00281): D00997 D08614
Tramazoline (DG01033): D01347 D08624
Trimazosin (DG00255): D06234 D08212
Urapidil (DG00257): D01333 D08662
Xylometazoline (DG01031): D00757 D08684
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    147 (ADRA1B)
   04022 cGMP-PKG signaling pathway
    147 (ADRA1B)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    147 (ADRA1B)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    147 (ADRA1B)
   04270 Vascular smooth muscle contraction
    147 (ADRA1B)
  09154 Digestive system
   04970 Salivary secretion
    147 (ADRA1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    147 (ADRA1B)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    147 (ADRA1B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx 7TM_GPCR_Srv Shisa
Motif
Other DBs
NCBI-GeneID: 147
NCBI-ProteinID: NP_000670
OMIM: 104220
HGNC: 278
Ensembl: ENSG00000170214
Vega: OTTHUMG00000130327
Pharos: P35368(Tclin)
UniProt: P35368
Position
5q33.3
AA seq 520 aa AA seqDB search
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
NT seq 1563 nt NT seq  +upstreamnt  +downstreamnt
atgaatcccgacctggacaccggccacaacacatcagcacctgcccactggggagagttg
aaaaatgccaacttcactggccccaaccagacctcgagcaactccacactgccccagctg
gacatcaccagggccatctctgtgggcctggtgctgggcgccttcatcctctttgccatc
gtgggcaacatcctagtcatcttgtctgtggcctgcaaccggcacctgcggacgcccacc
aactacttcattgtcaacctggccatggccgacctgctgttgagcttcaccgtcctgccc
ttctcagcggccctagaggtgctcggctactgggtgctggggcggatcttctgtgacatc
tgggcagccgtggatgtcctgtgctgcacagcgtccattctgagcctgtgcgccatctcc
atcgatcgctacatcggggtgcgctactctctgcagtatcccacgctggtcacccggagg
aaggccatcttggcgctgctcagtgtctgggtcttgtccaccgtcatctccatcgggcct
ctccttgggtggaaggagccggcacccaacgatgacaaggagtgcggggtcaccgaagaa
cccttctatgccctcttctcctctctgggctccttctacatccctctggcggtcattcta
gtcatgtactgccgtgtctatatagtggccaagagaaccaccaagaacctagaggcagga
gtcatgaaggagatgtccaactccaaggagctgaccctgaggatccattccaagaacttt
cacgaggacacccttagcagtaccaaggccaagggccacaaccccaggagttccatagct
gtcaaactttttaagttctccagggaaaagaaagcagctaagacgttgggcattgtggtc
ggtatgttcatcttgtgctggctacccttcttcatcgctctaccgcttggctccttgttc
tccaccctgaagccccccgacgccgtgttcaaggtggtgttctggctgggctacttcaac
agctgcctcaaccccatcatctacccatgctccagcaaggagttcaagcgcgctttcgtg
cgcatcctcgggtgccagtgccgcggccgcggccgccgccgacgccgccgccgccgtcgc
ctgggcggctgcgcctacacctaccggccgtggacgcgcggcggctcgctggagcgctcg
cagtcgcgcaaggactcgctggacgacagcggcagctgcctgagcggcagccagcggacc
ctgccctcggcctcgccgagcccgggctacctgggccgcggcgcgccaccgccagtcgag
ctgtgcgccttccccgagtggaaggcgcccggcgccctcctgagcctgcccgcgcctgag
ccccccggccgccgcggccgccacgactcgggcccgctcttcaccttcaagctcctgacc
gagcccgagagccccgggaccgacggcggcgccagcaacggaggctgcgaggccgcggcc
gacgtggccaacgggcagccgggcttcaaaagcaacatgcccctggcgcccgggcagttt
tag

KEGG   Homo sapiens (human): 148Help
Entry
148               CDS       T01001                                 

Gene name
ADRA1A, ADRA1C, ADRA1L1, ALPHA1AAR
Definition
(RefSeq) adrenoceptor alpha 1A
  KO
K04135  adrenergic receptor alpha-1A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion
Drug target
Adrenalone (DG00016): D02774 D07560
Alfuzosin (DG00489): D01692 D07124
Amidephrine mesylate: D02901
Amiodarone (DG00204): D00636 D02910
Amosulalol (DG01302): D01469 D07451
Arotinolol (DG01303): D01830 D07465
Bevantolol: D01369
Bunazosin (DG01316): D01887 D07550
Bunitrolol hydrochloride: D01444
Carvedilol (DG00321): D00255 D03415
Dabuzalgron hydrochloride: D06394
Dapiprazole (DG01140): D03648 D07775
Dihydroergocristine (DG00284): D07833 D07834
Dipivefrine (DG01129): D01017 D02349
Domazoline fumarate: D03887
Doxazosin (DG00256): D00608 D07874
Dronedarone (DG00207): D02537 D03914
Droperidol: D00308
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Ergoloid mesylates: D02268
Ergometrine (DG00446): D01163 D07905
Ergot alkaloids: D07906
Ergotamine (DG00834): D00679
Etilefrine (DG00210): D01573 D07931
Fiduxosin hydrochloride: D04184
Flesinoxan: D02568
Garomefrine hydrochloride: D09784
Guanadrel: D08029
Guanadrel sulfate: D00607
Ifenprodil (DG00292): D01445 D08064
Indoramin (DG00254): D04531 D04532
Isometheptene: D07097
Labetalol (DG00320): D00600 D08106
Levobunolol (DG01136): D01025 D08115
Metaraminol (DG00218): D01019 D08192
Methoxamine (DG00219): D01020 D08201
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Methylergometrine (DG00445): D00680 D08207
Midodrine (DG00224): D01307 D08220
Monatepil maleate: D01171
Moxisylyte (DG00287): D01571 D08239
Naftopidil: D01674
Naphazoline (DG01032): D00743 D01021 D08253
Nefazodone (DG00953): D00819 D08257
Nicergoline (DG00283): D01290 D08271
Nipradilol: D01691
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Olanzapine (DG00898): D00454 D06623
Oxymetazoline (DG01029): D01022 D08322
Pelanserin hydrochloride: D05395
Periciazine: D01485
Phenoxybenzamine (DG00285): D00507 D08358
Phentolamine (DG00280): D00509 D08362
Phenylephrine (DG00215): D00511 D08365 D08366 D08966
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Prazosin (DG00253): D00609 D08411
Propylhexedrine (DG01919): D05637 D08444
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Silodosin: D01965
Tamsulosin (DG00490): D01024 D08560
Terazosin (DG00491): D00610 D08569 D11585
Tetryzoline (DG01030): D00756 D01023 D08578
Tolazoline (DG00281): D00997 D08614
Tramazoline (DG01033): D01347 D08624
Trimazosin (DG00255): D06234 D08212
Urapidil (DG00257): D01333 D08662
Xylometazoline (DG01031): D00757 D08684
Zolertine hydrochloride: D06380
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    148 (ADRA1A)
   04022 cGMP-PKG signaling pathway
    148 (ADRA1A)
   04152 AMPK signaling pathway
    148 (ADRA1A)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    148 (ADRA1A)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    148 (ADRA1A)
   04270 Vascular smooth muscle contraction
    148 (ADRA1A)
  09154 Digestive system
   04970 Salivary secretion
    148 (ADRA1A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    148 (ADRA1A)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    148 (ADRA1A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4
Motif
Other DBs
NCBI-GeneID: 148
NCBI-ProteinID: NP_000671
OMIM: 104221
HGNC: 277
Ensembl: ENSG00000120907
Vega: OTTHUMG00000099459
Pharos: P35348(Tclin)
UniProt: P35348
Position
8p21.2
AA seq 466 aa AA seqDB search
MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
APAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTL
HPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCT
TARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV
NT seq 1401 nt NT seq  +upstreamnt  +downstreamnt
atggtgtttctctcgggaaatgcttccgacagctccaactgcacccaaccgccggcaccg
gtgaacatttccaaggccattctgctcggggtgatcttggggggcctcattcttttcggg
gtgctgggtaacatcctagtgatcctctccgtagcctgtcaccgacacctgcactcagtc
acgcactactacatcgtcaacctggcggtggccgacctcctgctcacctccacggtgctg
cccttctccgccatcttcgaggtcctaggctactgggccttcggcagggtcttctgcaac
atctgggcggcagtggatgtgctgtgctgcaccgcgtccatcatgggcctctgcatcatc
tccatcgaccgctacatcggcgtgagctacccgctgcgctacccaaccatcgtcacccag
aggaggggtctcatggctctgctctgcgtctgggcactctccctggtcatatccattgga
cccctgttcggctggaggcagccggcccccgaggacgagaccatctgccagatcaacgag
gagccgggctacgtgctcttctcagcgctgggctccttctacctgcctctggccatcatc
ctggtcatgtactgccgcgtctacgtggtggccaagagggagagccggggcctcaagtct
ggcctcaagaccgacaagtcggactcggagcaagtgacgctccgcatccatcggaaaaac
gccccggcaggaggcagcgggatggccagcgccaagaccaagacgcacttctcagtgagg
ctcctcaagttctcccgggagaagaaagcggccaaaacgctgggcatcgtggtcggctgc
ttcgtcctctgctggctgccttttttcttagtcatgcccattgggtctttcttccctgat
ttcaagccctctgaaacagtttttaaaatagtattttggctcggatatctaaacagctgc
atcaaccccatcatatacccatgctccagccaagagttcaaaaaggcctttcagaatgtc
ttgagaatccagtgtctctgcagaaagcagtcttccaaacatgccctgggctacaccctg
cacccgcccagccaggccgtggaagggcaacacaaggacatggtgcgcatccccgtggga
tcaagagagaccttctacaggatctccaagacggatggcgtttgtgaatggaaatttttc
tcttccatgccccgtggatctgccaggattacagtgtccaaagaccaatcctcctgtacc
acagcccgggtgagaagtaaaagctttttgcaggtctgctgctgtgtagggccctcaacc
cccagccttgacaagaaccatcaagttccaaccattaaggtccacaccatctccctcagt
gagaacggggaggaagtctag

KEGG   Homo sapiens (human): 150Help
Entry
150               CDS       T01001                                 

Gene name
ADRA2A, ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Definition
(RefSeq) adrenoceptor alpha 2A
  KO
K04138  adrenergic receptor alpha-2A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Apraclonidine (DG01130): D01008 D07461
Aptazapine maleate: D02972
Atipamezole: D03002
Betanidine: D01603
Brimonidine (DG00442): D02076 D07540
Chlorpromazine (DG00867): D00270 D00789 D03274 D04034 D09819
Clonidine (DG00249): D00281 D00604
Clozapine: D00283
Delequamine hydrochloride: D03672
Detomidine (DG01318): D03702 D07795
Dexmedetomidine (DG00926): D00514 D01205
Dihydroergocristine (DG00284): D07833 D07834
Dipivefrine (DG01129): D01017 D02349
Domazoline fumarate: D03887
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Ergoloid mesylates: D02268
Ergometrine (DG00446): D01163 D07905
Etilefrine (DG00210): D01573 D07931
Fadolmidine hydrochloride: D04124
Fluparoxan hydrochloride: D04223
Guanabenz (DG01230): D00605 D04375
Guanadrel: D08029
Guanadrel sulfate: D00607
Guanfacine (DG00250): D00606 D08031
Levonordefrin: D02388
Lidamidine (DG02870): D02407 D08126
Lofexidine (DG01001): D04765 D08141
Medetomidine (DG01320): D04883 D08165
Metaraminol (DG00218): D01019 D08192
Methyldopa (levorotatory) (DG00248): D00405 D08205
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Methylergometrine (DG00445): D00680 D08207
Mianserin (DG00951): D01358 D08216
Mirtazapine (DG02838): D00563 D11056
Moxonidine: D05087
Napamezole hydrochloride: D05119
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Phenoxybenzamine (DG00285): D00507 D08358
Phentolamine (DG00280): D00509 D08362
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Propylhexedrine (DG01919): D05637 D08444
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Rilmenidine: D08482
Romifidine: D08487
Setiptiline (DG01231): D02034 D08511
Sunepitron hydrochloride: D02569
Tizanidine (DG00773): D00776 D08611
Tolazoline (DG00281): D00997 D08614
Tramazoline (DG01033): D01347 D08624
Vatinoxan (DG02987): D11320 D11321
Xylazine (DG01321): D06344 D08683
Xylometazoline (DG01031): D00757 D08684
Yohimbin (DG00485): D06671 D08685
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    150 (ADRA2A)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    150 (ADRA2A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    150 (ADRA2A)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    150 (ADRA2A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7tm_4 7TM_GPCR_Srsx 7TM_GPCR_Srx T2SSM
Motif
Other DBs
NCBI-GeneID: 150
NCBI-ProteinID: NP_000672
OMIM: 104210
HGNC: 281
Ensembl: ENSG00000150594
Vega: OTTHUMG00000019050
Pharos: P08913(Tclin)
UniProt: P08913
Position
10q25.2
AA seq 465 aa AA seqDB search
MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLML
LTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAW
CEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVIS
FPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKR
RTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGP
RDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTP
AAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPR
TLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt
atgttccgccaggagcagccgttggccgagggcagctttgcgcccatgggctccctgcag
ccggacgcgggcaacgcgagctggaacgggaccgaggcgccggggggcggcgcccgggcc
accccttactccctgcaggtgacgctgacgctggtgtgcctggccggcctgctcatgctg
ctcaccgtgttcggcaacgtgctcgtcatcatcgccgtgttcacgagccgcgcgctcaag
gcgccccaaaacctcttcctggtgtctctggcctcggccgacatcctggtggccacgctc
gtcatccctttctcgctggccaacgaggtcatgggctactggtacttcggcaaggcttgg
tgcgagatctacctggcgctcgacgtgctcttctgcacgtcgtccatcgtgcacctgtgc
gccatcagcctggaccgctactggtccatcacacaggccatcgagtacaacctgaagcgc
acgccgcgccgcatcaaggccatcatcatcaccgtgtgggtcatctcggccgtcatctcc
ttcccgccgctcatctccatcgagaagaagggcggcggcggcggcccgcagccggccgag
ccgcgctgcgagatcaacgaccagaagtggtacgtcatctcgtcgtgcatcggctccttc
ttcgctccctgcctcatcatgatcctggtctacgtgcgcatctaccagatcgccaagcgt
cgcacccgcgtgccacccagccgccggggtccggacgccgtcgccgcgccgccggggggc
accgagcgcaggcccaacggtctgggccccgagcgcagcgcgggcccggggggcgcagag
gccgaaccgctgcccacccagctcaacggcgcccctggcgagcccgcgccggccgggccg
cgcgacaccgacgcgctggacctggaggagagctcgtcttccgaccacgccgagcggcct
ccagggccccgcagacccgagcgcggtccccggggcaaaggcaaggcccgagcgagccag
gtgaagccgggcgacagcctgccgcggcgcgggccgggggcgacggggatcgggacgccg
gctgcagggccgggggaggagcgcgtcggggctgccaaggcgtcgcgctggcgcgggcgg
cagaaccgcgagaagcgcttcacgttcgtgctggccgtggtcatcggagtgttcgtggtg
tgctggttccccttcttcttcacctacacgctcacggccgtcgggtgctccgtgccacgc
acgctcttcaaattcttcttctggttcggctactgcaacagctcgttgaacccggtcatc
tacaccatcttcaaccacgatttccgccgcgccttcaagaagatcctctgtcggggggac
aggaagcggatcgtgtga

KEGG   Homo sapiens (human): 151Help
Entry
151               CDS       T01001                                 

Gene name
ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR
Definition
(RefSeq) adrenoceptor alpha 2B
  KO
K04139  adrenergic receptor alpha-2B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Disease
H02213  Familial adult myoclonic epilepsy
Drug target
Apraclonidine (DG01130): D01008 D07461
Aptazapine maleate: D02972
Atipamezole: D03002
Betanidine: D01603
Brimonidine (DG00442): D02076 D07540
Chlorpromazine (DG00867): D00270 D00789 D03274 D04034 D09819
Clonidine (DG00249): D00281 D00604
Clozapine: D00283
Delequamine hydrochloride: D03672
Detomidine (DG01318): D03702 D07795
Dexmedetomidine (DG00926): D00514 D01205
Dihydroergocristine (DG00284): D07833 D07834
Dipivefrine (DG01129): D01017 D02349
Domazoline fumarate: D03887
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Ergoloid mesylates: D02268
Ergometrine (DG00446): D01163 D07905
Etilefrine (DG00210): D01573 D07931
Fadolmidine hydrochloride: D04124
Fluparoxan hydrochloride: D04223
Guanabenz (DG01230): D00605 D04375
Guanadrel: D08029
Guanadrel sulfate: D00607
Imiloxan hydrochloride: D04514
Levonordefrin: D02388
Lidamidine (DG02870): D02407 D08126
Lofexidine (DG01001): D04765 D08141
Medetomidine (DG01320): D04883 D08165
Metaraminol (DG00218): D01019 D08192
Methyldopa (levorotatory) (DG00248): D00405 D08205
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Methylergometrine (DG00445): D00680 D08207
Mianserin (DG00951): D01358 D08216
Mirtazapine (DG02838): D00563 D11056
Moxonidine: D05087
Napamezole hydrochloride: D05119
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Phenoxybenzamine (DG00285): D00507 D08358
Phentolamine (DG00280): D00509 D08362
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Propylhexedrine (DG01919): D05637 D08444
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Rilmenidine: D08482
Romifidine: D08487
Setiptiline (DG01231): D02034 D08511
Sunepitron hydrochloride: D02569
Tizanidine (DG00773): D00776 D08611
Tolazoline (DG00281): D00997 D08614
Tramazoline (DG01033): D01347 D08624
Vatinoxan (DG02987): D11320 D11321
Xylazine (DG01321): D06344 D08683
Xylometazoline (DG01031): D00757 D08684
Yohimbin (DG00485): D06671 D08685
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    151 (ADRA2B)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    151 (ADRA2B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    151 (ADRA2B)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    151 (ADRA2B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx Na_Ca_ex DUF4632
Motif
Other DBs
NCBI-GeneID: 151
NCBI-ProteinID: NP_000673
OMIM: 104260
HGNC: 282
Ensembl: ENSG00000274286
Vega: OTTHUMG00000188276
Pharos: P18089(Tclin)
UniProt: P18089
Position
2q11.2
AA seq 450 aa AA seqDB search
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
NT seq 1353 nt NT seq  +upstreamnt  +downstreamnt
atggaccaccaggacccctactccgtgcaggccacagcggccatagcggcggccatcacc
ttcctcattctctttaccatcttcggcaacgctctggtcatcctggctgtgttgaccagc
cgctcgctgcgcgcccctcagaacctgttcctggtgtcgctggccgccgccgacatcctg
gtggccacgctcatcatccctttctcgctggccaacgagctgctgggctactggtacttc
cggcgcacgtggtgcgaggtgtacctggcgctcgacgtgctcttctgcacctcgtccatc
gtgcacctgtgcgccatcagcctggaccgctactgggccgtgagccgcgcgctggagtac
aactccaagcgcaccccgcgccgcatcaagtgcatcatcctcactgtgtggctcatcgcc
gccgtcatctcgctgccgcccctcatctacaagggcgaccagggcccccagccgcgcggg
cgcccccagtgcaagctcaaccaggaggcctggtacatcctggcctccagcatcggatct
ttctttgctccttgcctcatcatgatccttgtctacctgcgcatctacctgatcgccaaa
cgcagcaaccgcagaggtcccagggccaagggggggcctgggcagggtgagtccaagcag
ccccgacccgaccatggtggggctttggcctcagccaaactgccagccctggcctctgtg
gcttctgccagagaggtcaacggacactcgaagtccactggggagaaggaggagggggag
acccctgaagatactgggacccgggccttgccacccagttgggctgcccttcccaactca
ggccagggccagaaggagggtgtttgtggggcatctccagaggatgaagctgaagaggag
gaagaggaggaggaggaggaggaagagtgtgaaccccaggcagtgccagtgtctccggcc
tcagcttgcagccccccgctgcagcagccacagggctcccgggtgctggccaccctacgt
ggccaggtgctcctgggcaggggcgtgggtgctataggtgggcagtggtggcgtcgacgg
gcgcagctgacccgggagaagcgcttcaccttcgtgctggctgtggtcattggcgttttt
gtgctctgctggttccccttcttcttcagctacagcctgggagccatctgcccgaagcac
tgcaaggtgccccatggcctcttccagttcttcttctggatcggctactgcaacagctca
ctgaaccctgttatctacaccatcttcaaccaggacttccgccgtgccttccggaggatc
ctgtgccgcccgtggacccagacggcctggtga

KEGG   Homo sapiens (human): 152Help
Entry
152               CDS       T01001                                 

Gene name
ADRA2C, ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
Definition
(RefSeq) adrenoceptor alpha 2C
  KO
K04140  adrenergic receptor alpha-2C
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Apraclonidine (DG01130): D01008 D07461
Aptazapine maleate: D02972
Atipamezole: D03002
Betanidine: D01603
Brimonidine (DG00442): D02076 D07540
Chlorpromazine (DG00867): D00270 D00789 D03274 D04034 D09819
Clonidine (DG00249): D00281 D00604
Clozapine: D00283
Delequamine hydrochloride: D03672
Detomidine (DG01318): D03702 D07795
Dexmedetomidine (DG00926): D00514 D01205
Dihydroergocristine (DG00284): D07833 D07834
Dipivefrine (DG01129): D01017 D02349
Domazoline fumarate: D03887
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Ergoloid mesylates: D02268
Ergometrine (DG00446): D01163 D07905
Etilefrine (DG00210): D01573 D07931
Fadolmidine hydrochloride: D04124
Fluparoxan hydrochloride: D04223
Guanabenz (DG01230): D00605 D04375
Guanadrel: D08029
Guanadrel sulfate: D00607
Levonordefrin: D02388
Lidamidine (DG02870): D02407 D08126
Lofexidine (DG01001): D04765 D08141
Medetomidine (DG01320): D04883 D08165
Metaraminol (DG00218): D01019 D08192
Methyldopa (levorotatory) (DG00248): D00405 D08205
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Methylergometrine (DG00445): D00680 D08207
Mianserin (DG00951): D01358 D08216
Mirtazapine (DG02838): D00563 D11056
Moxonidine: D05087
Napamezole hydrochloride: D05119
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Phenoxybenzamine (DG00285): D00507 D08358
Phentolamine (DG00280): D00509 D08362
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Propylhexedrine (DG01919): D05637 D08444
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Rilmenidine: D08482
Romifidine: D08487
Setiptiline (DG01231): D02034 D08511
Sunepitron hydrochloride: D02569
Tizanidine (DG00773): D00776 D08611
Tolazoline (DG00281): D00997 D08614
Tramazoline (DG01033): D01347 D08624
Vatinoxan (DG02987): D11320 D11321
Xylazine (DG01321): D06344 D08683
Xylometazoline (DG01031): D00757 D08684
Yohimbin (DG00485): D06671 D08685
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    152 (ADRA2C)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    152 (ADRA2C)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    152 (ADRA2C)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    152 (ADRA2C)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx
Motif
Other DBs
NCBI-GeneID: 152
NCBI-ProteinID: NP_000674
OMIM: 104250
HGNC: 283
Ensembl: ENSG00000184160
Vega: OTTHUMG00000159830
Pharos: P18825(Tclin)
UniProt: P18825 Q4W594
Position
4p16.3
AA seq 462 aa AA seqDB search
MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
NT seq 1389 nt NT seq  +upstreamnt  +downstreamnt
atggcgtccccggcgctggcggcggcgctggcggtggcggcagcggcgggccccaatgcg
agcggcgcgggcgagaggggcagcggcggggttgccaatgcctcgggggcttcctggggg
ccgccgcgcggccagtactcggcgggcgcggtggcagggctggctgccgtggtgggcttc
ctcatcgtcttcaccgtggtgggcaacgtgctggtggtgatcgccgtgctgaccagccgg
gcgctgcgcgcgccacagaacctcttcctggtgtcgctggcctcggccgacatcctggtg
gccacgctggtcatgcccttctcgttggccaacgagctcatggcctactggtacttcggg
caggtgtggtgcggcgtgtacctggcgctcgatgtgctgttttgcacctcgtcgatcgtg
catctgtgtgccatcagcctggaccgctactggtcggtgacgcaggccgtcgagtacaac
ctgaagcgcacaccacgccgcgtcaaggccaccatcgtggccgtgtggctcatctcggcc
gtcatctccttcccgccgctggtctcgctctaccgccagcccgacggcgccgcctacccg
cagtgcggcctcaacgacgagacctggtacatcctgtcctcctgcatcggctccttcttc
gcgccctgcctcatcatgggcctggtctacgcgcgcatctaccgagtggccaagctgcgc
acgcgcacgctcagcgagaagcgcgcccccgtgggccccgacggtgcgtccccgactacc
gaaaacgggctgggcgcggcggcaggcgcaggcgagaacgggcactgcgcgcccccgccc
gccgacgtggagccggacgagagcagcgcagcggccgagaggcggcggcgccggggcgcg
ttgcggcggggcgggcggcggcgagcgggcgcggaggggggcgcgggcggtgcggacggg
cagggggcggggccgggggcggctgagtcgggggcgctgaccgcctccaggtccccgggg
cccggtggccgcctgtcgcgcgccagctcgcgctccgtcgagttcttcctgtcgcgccgg
cgccgggcgcgcagcagcgtgtgccgccgcaaggtggcccaggcgcgcgagaagcgcttc
acctttgtgctggctgtggtcatgggcgtgttcgtgctctgctggttccccttcttcttc
agctacagcctgtacggcatctgccgcgaggcctgccaggtgcccggcccgctcttcaag
ttcttcttctggatcggctactgcaacagctcgctcaacccggtcatctacacggtcttc
aaccaggatttccggcgatcctttaagcacatcctcttccgacggaggagaaggggcttc
aggcagtga

KEGG   Homo sapiens (human): 153Help
Entry
153               CDS       T01001                                 

Gene name
ADRB1, ADRB1R, B1AR, BETA1AR, RHR
Definition
(RefSeq) adrenoceptor beta 1
  KO
K04141  adrenergic receptor beta-1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04540  Gap junction
hsa04923  Regulation of lipolysis in adipocytes
hsa04924  Renin secretion
hsa04970  Salivary secretion
hsa05414  Dilated cardiomyopathy (DCM)
Drug target
Acebutolol (DG00314): D00597 D02338
Adaprolol maleate: D02765
Alprenolol (DG00303): D01182 D07156
Alprenoxime hydrochloride: D02834
Amiodarone (DG00204): D00636 D02910
Amosulalol (DG01302): D01469 D07451
Arbutamine: D02976
Arotinolol (DG01303): D01830 D07465
Atenolol: D00235
Befunolol (DG01138): D01512 D07496
Beradilol monoethyl maleate: D09843
Betaxolol (DG00315): D00598 D07526
Bevantolol: D01369
Bisoprolol (DG00316): D00634 D02342
Bopindolol (DG00310): D01794 D07537
Bucumolol hydrochloride: D01492
Bufetolol hydrochloride: D01504
Bunitrolol hydrochloride: D01444
Bunolol hydrochloride: D03177
Bupranolol (DG00311): D01454 D07590
Butopamine: D03195
Carteolol (DG00308): D00599 D07624
Carvedilol (DG00321): D00255 D03415
Celiprolol (DG00317): D01741 D07660
Cetamolol hydrochloride: D03449
Cicloprolol hydrochloride: D03490
Cimaterol: D03502
Cloranolol: D07183
Denopamine: D02614
Dexpropranolol hydrochloride: D03729
Diacetolol hydrochloride: D03759
Dilevalol hydrochloride: D01906
Dipivefrine (DG01129): D01017 D02349
Dobutamine (DG00216): D00632 D03879 D03880 D03881
Docarpamine: D01903
Dronedarone (DG00207): D02537 D03914
Droxidopa: D01277
Epanolol: D06646
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Esmolol (DG00318): D00644 D07916
Etilefrine (DG00210): D01573 D07931
Exaprolol hydrochloride: D04120
Flestolol sulfate: D04190
Indenolol (DG01323): D01958 D08078
Isoprenaline (DG00211): D01390 D02066 D02150 D08090
Labetalol (DG00320): D00600 D08106
Landiolol: D01847
Levdobutamine lactobionate: D04708
Levobetaxolol hydrochloride: D04710
Levobunolol (DG01136): D01025 D08115
Medroxalol (DG01317): D04888 D04889
Mepindolol: D07181
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Metipranolol (DG01137): D02081 D02374
Metoprolol (DG00313): D00601 D00635 D02358 D05011
Nadolol: D00432
Nebivolol (DG00319): D05127 D06622
Nipradilol: D01691
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Oxprenolol (DG00304): D01806 D08318
Pamatolol sulfate: D05345
Penbutolol (DG00312): D00602 D08074
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Pindolol: D00513
Practolol: D05587
Primidolol: D02389
Propranolol (DG00305): D00483 D08443
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
S-atenolol: D01471
Sotalol (DG00307): D01026 D08525
Talinolol: D07184
Tazolol hydrochloride: D06014
Tertatolol (DG00309): D07182 D08572
Tilisolol (DG01322): D01795 D08598
Timolol (DG00306): D00378 D00603 D08600
Tiprenolol hydrochloride: D06162
Tolamolol: D06176
Xamoterol (DG00231): D06328 D06329
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    153 (ADRB1)
   04024 cAMP signaling pathway
    153 (ADRB1)
   04022 cGMP-PKG signaling pathway
    153 (ADRB1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    153 (ADRB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    153 (ADRB1)
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    153 (ADRB1)
   04924 Renin secretion
    153 (ADRB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    153 (ADRB1)
  09154 Digestive system
   04970 Salivary secretion
    153 (ADRB1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    153 (ADRB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    153 (ADRB1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    153 (ADRB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7TM_GPCR_Srv 7tm_4
Motif
Other DBs
NCBI-GeneID: 153
NCBI-ProteinID: NP_000675
OMIM: 109630
HGNC: 285
Ensembl: ENSG00000043591
Vega: OTTHUMG00000019079
Pharos: P08588(Tclin)
UniProt: P08588
Position
10q25.3
AA seq 477 aa AA seqDB search
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
NT seq 1434 nt NT seq  +upstreamnt  +downstreamnt
atgggcgcgggggtgctcgtcctgggcgcctccgagcccggtaacctgtcgtcggccgca
ccgctccccgacggcgcggccaccgcggcgcggctgctggtgcccgcgtcgccgcccgcc
tcgttgctgcctcccgccagcgaaagccccgagccgctgtctcagcagtggacagcgggc
atgggtctgctgatggcgctcatcgtgctgctcatcgtggcgggcaatgtgctggtgatc
gtggccatcgccaagacgccgcggctgcagacgctcaccaacctcttcatcatgtccctg
gccagcgccgacctggtcatggggctgctggtggtgccgttcggggccaccatcgtggtg
tggggccgctgggagtacggctccttcttctgcgagctgtggacctcagtggacgtgctg
tgcgtgacggccagcatcgagaccctgtgtgtcattgccctggaccgctacctcgccatc
acctcgcccttccgctaccagagcctgctgacgcgcgcgcgggcgcggggcctcgtgtgc
accgtgtgggccatctcggccctggtgtccttcctgcccatcctcatgcactggtggcgg
gcggagagcgacgaggcgcgccgctgctacaacgaccccaagtgctgcgacttcgtcacc
aaccgggcctacgccatcgcctcgtccgtagtctccttctacgtgcccctgtgcatcatg
gccttcgtgtacctgcgggtgttccgcgaggcccagaagcaggtgaagaagatcgacagc
tgcgagcgccgtttcctcggcggcccagcgcggccgccctcgccctcgccctcgcccgtc
cccgcgcccgcgccgccgcccggacccccgcgccccgccgccgccgccgccaccgccccg
ctggccaacgggcgtgcgggtaagcggcggccctcgcgcctcgtggccctgcgcgagcag
aaggcgctcaagacgctgggcatcatcatgggcgtcttcacgctctgctggctgcccttc
ttcctggccaacgtggtgaaggccttccaccgcgagctggtgcccgaccgcctcttcgtc
ttcttcaactggctgggctacgccaactcggccttcaaccccatcatctactgccgcagc
cccgacttccgcaaggccttccagggactgctctgctgcgcgcgcagggctgcccgccgg
cgccacgcgacccacggagaccggccgcgcgcctcgggctgtctggcccggcccggaccc
ccgccatcgcccggggccgcctcggacgacgacgacgacgatgtcgtcggggccacgccg
cccgcgcgcctgctggagccctgggccggctgcaacggcggggcggcggcggacagcgac
tcgagcctggacgagccgtgccgccccggcttcgcctcggaatccaaggtgtag

KEGG   Homo sapiens (human): 154Help
Entry
154               CDS       T01001                                 

Gene name
ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Definition
(RefSeq) adrenoceptor beta 2
  KO
K04142  adrenergic receptor beta-2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04923  Regulation of lipolysis in adipocytes
hsa04924  Renin secretion
hsa04970  Salivary secretion
Disease
H00079  Asthma
H02106  Genetic obesity
Drug target
Abediterol (DG01232): D10219 D10220
Adaprolol maleate: D02765
Alprenolol (DG00303): D01182 D07156
Alprenoxime hydrochloride: D02834
Amosulalol (DG01302): D01469 D07451
Arformoterol (DG01233): D02981 D07463
Arotinolol (DG01303): D01830 D07465
Bambuterol (DG01060): D07377 D07489
Batefenterol (DG01627): D10545 D10546
Bedoradrine sulfate: D06562
Befunolol (DG01138): D01512 D07496
Beradilol monoethyl maleate: D09843
Bitolterol (DG01056): D00684 D07534
Bopindolol (DG00310): D01794 D07537
Bucindolol hydrochloride: D03170
Bucumolol hydrochloride: D01492
Bufetolol hydrochloride: D01504
Bunitrolol hydrochloride: D01444
Bunolol hydrochloride: D03177
Bupranolol (DG00311): D01454 D07590
Butoxamine hydrochloride: D03198
Carazolol: D07608
Carbuterol: D03402
Carteolol (DG00308): D00599 D07624
Carvedilol (DG00321): D00255 D03415
Cimaterol: D03502
Clenbuterol (DG01053): D01360 D07713
Cloranolol: D07183
Clorprenaline hydrochloride: D01835
Colterol mesylate: D03587
Dexpropranolol hydrochloride: D03729
Diacetolol hydrochloride: D03759
Dilevalol hydrochloride: D01906
Dipivefrine (DG01129): D01017 D02349
Dopexamine (DG00222): D03891 D03892
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Etafedrine hydrochloride: D04072
Etilefrine (DG00210): D01573 D07931
Exaprolol hydrochloride: D04120
Fenoterol (DG00451): D01428 D04157
Flestolol sulfate: D04190
Formoterol (DG01052): D01373 D05277 D07990
Hexoprenaline (DG01047): D02396 D08039
Indacaterol (DG01057): D09318 D09319 D11009
Indenolol (DG01323): D01958 D08078
Isoetarine (DG01234): D02093 D04625 D04626
Isoprenaline (DG00211): D01390 D02066 D02150 D08090
Isoxsuprine (DG00277): D01748 D08092 D08093
Labetalol (DG00320): D00600 D08106
Levalbuterol  
Levosalbutamol (DG01235): D02281 D04701 D04703 D08124
Levobunolol (DG01136): D01025 D08115
Mabuterol hydrochloride: D01589
Medroxalol (DG01317): D04888 D04889
Mepindolol: D07181
Metalol hydrochloride: D04953
Methoxyphenamine: D01635
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Metipranolol (DG01137): D02081 D02374
Milveterol hydrochloride: D08945
Nadolol: D00432
Nipradilol: D01691
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Olodaterol (DG01058): D10020 D10145
Orciprenaline (DG01044): D00685 D04954 D08300
Oxprenolol (DG00304): D01806 D08318
Pamatolol sulfate: D05345
Penbutolol (DG00312): D00602 D08074
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Picumeterol fumarate: D05476
Pindolol: D00513
Pirbuterol (DG01048): D00686 D01349 D08387
Primidolol: D02389
Procaterol (DG01055): D02404 D05366 D08424
Propranolol (DG00305): D00483 D08443
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Ractopamine hydrochloride: D05691
Reproterol (DG01054): D05718 D08474
Rimiterol: D05730
Ritodrine (DG00450): D01263 D02359
Salbutamol (DG01045): D00683 D02147
Salmeterol (DG01051): D00687 D05792
Sibenadet hydrochloride: D05832
Sotalol (DG00307): D01026 D08525
Soterenol hydrochloride: D05902
Talinolol: D07184
Tazolol hydrochloride: D06014
Terbutaline (DG01046): D00688 D08570
Tertatolol (DG00309): D07182 D08572
Tilisolol (DG01322): D01795 D08598
Timolol (DG00306): D00378 D00603 D08600
Tiprenolol hydrochloride: D06162
Tolamolol: D06176
Tretoquinol (DG01049): D01978 D05037 D08629
Tulobuterol (DG01050): D01362 D02151
Vilanterol (DG01236): D09696 D09697
Zinterol hydrochloride: D06374
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    154 (ADRB2)
   04024 cAMP signaling pathway
    154 (ADRB2)
   04022 cGMP-PKG signaling pathway
    154 (ADRB2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    154 (ADRB2)
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    154 (ADRB2)
   04924 Renin secretion
    154 (ADRB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    154 (ADRB2)
  09154 Digestive system
   04970 Salivary secretion
    154 (ADRB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    154 (ADRB2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    154 (ADRB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4 7TM_GPCR_Srv
Motif
Other DBs
NCBI-GeneID: 154
NCBI-ProteinID: NP_000015
OMIM: 109690
HGNC: 286
Ensembl: ENSG00000169252
Vega: OTTHUMG00000129933
Pharos: P07550(Tclin)
UniProt: P07550
Structure
PDB: 

Position
5q32
AA seq 413 aa AA seqDB search
MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
NT seq 1242 nt NT seq  +upstreamnt  +downstreamnt
atggggcaacccgggaacggcagcgccttcttgctggcacccaatagaagccatgcgccg
gaccacgacgtcacgcagcaaagggacgaggtgtgggtggtgggcatgggcatcgtcatg
tctctcatcgtcctggccatcgtgtttggcaatgtgctggtcatcacagccattgccaag
ttcgagcgtctgcagacggtcaccaactacttcatcacttcactggcctgtgctgatctg
gtcatgggcctggcagtggtgccctttggggccgcccatattcttatgaaaatgtggact
tttggcaacttctggtgcgagttttggacttccattgatgtgctgtgcgtcacggccagc
attgagaccctgtgcgtgatcgcagtggatcgctactttgccattacttcacctttcaag
taccagagcctgctgaccaagaataaggcccgggtgatcattctgatggtgtggattgtg
tcaggccttacctccttcttgcccattcagatgcactggtaccgggccacccaccaggaa
gccatcaactgctatgccaatgagacctgctgtgacttcttcacgaaccaagcctatgcc
attgcctcttccatcgtgtccttctacgttcccctggtgatcatggtcttcgtctactcc
agggtctttcaggaggccaaaaggcagctccagaagattgacaaatctgagggccgcttc
catgtccagaaccttagccaggtggagcaggatgggcggacggggcatggactccgcaga
tcttccaagttctgcttgaaggagcacaaagccctcaagacgttaggcatcatcatgggc
actttcaccctctgctggctgcccttcttcatcgttaacattgtgcatgtgatccaggat
aacctcatccgtaaggaagtttacatcctcctaaattggataggctatgtcaattctggt
ttcaatccccttatctactgccggagcccagatttcaggattgccttccaggagcttctg
tgcctgcgcaggtcttctttgaaggcctatgggaatggctactccagcaacggcaacaca
ggggagcagagtggatatcacgtggaacaggagaaagaaaataaactgctgtgtgaagac
ctcccaggcacggaagactttgtgggccatcaaggtactgtgcctagcgataacattgat
tcacaagggaggaattgtagtacaaatgactcactgctgtaa

KEGG   Homo sapiens (human): 155Help
Entry
155               CDS       T01001                                 

Gene name
ADRB3, BETA3AR
Definition
(RefSeq) adrenoceptor beta 3
  KO
K04143  adrenergic receptor beta-3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04714  Thermogenesis
hsa04923  Regulation of lipolysis in adipocytes
hsa04924  Renin secretion
hsa04970  Salivary secretion
Disease
H02106  Genetic obesity
Drug target
Adaprolol maleate: D02765
Alprenolol (DG00303): D01182 D07156
Alprenoxime hydrochloride: D02834
Amibegron (DG01237): D08850 D08851
Befunolol (DG01138): D01512 D07496
Beradilol monoethyl maleate: D09843
Bopindolol (DG00310): D01794 D07537
Bufetolol hydrochloride: D01504
Bunitrolol hydrochloride: D01444
Bunolol hydrochloride: D03177
Bupranolol (DG00311): D01454 D07590
Carteolol (DG00308): D00599 D07624
Cimaterol: D03502
Cloranolol: D07183
Dexpropranolol hydrochloride: D03729
Diacetolol hydrochloride: D03759
Dilevalol hydrochloride: D01906
Dipivefrine (DG01129): D01017 D02349
Droxidopa: D01277
Ephedrine (DG00227): D00124 D01386 D04018
Epinephrine (DG00013): D00095 D00996 D02149
Epinephryl borate: D04026
Etilefrine (DG00210): D01573 D07931
Exaprolol hydrochloride: D04120
Fasobegron: D09344
Flestolol sulfate: D04190
Isoprenaline (DG00211): D01390 D02066 D02150 D08090
Levobunolol (DG01136): D01025 D08115
Medroxalol (DG01317): D04888 D04889
Mepindolol: D07181
Methylephedrine (DG01229): D01952 D02109 D08206 D09842
Metipranolol (DG01137): D02081 D02374
Mirabegron: D09535
Nipradilol: D01691
Norepinephrine (DG00212): D00076 D05206 D08284 D09794
Octodrine: D05228
Oxprenolol (DG00304): D01806 D08318
Pamatolol sulfate: D05345
Penbutolol (DG00312): D00602 D08074
Phenylpropanolamine (DG01041): D01224 D05466 D08368
Pindolol: D00513
Primidolol: D02389
Propranolol (DG00305): D00483 D08443
Pseudoephedrine (DG01042): D00485 D05648 D05649 D08449
Racephedrine Hydrochloride: D08982
Racepinephrine (DG01444): D05688 D05689
Ritobegron ethyl hydrochloride: D09732
Solabegron hydrochloride: D05879
Talibegron hydrochloride: D02702
Talinolol: D07184
Tazolol hydrochloride: D06014
Tertatolol (DG00309): D07182 D08572
Tilisolol (DG01322): D01795 D08598
Tiprenolol hydrochloride: D06162
Tolamolol: D06176
Vibegron: D10433
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    155 (ADRB3)
   04022 cGMP-PKG signaling pathway
    155 (ADRB3)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    155 (ADRB3)
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    155 (ADRB3)
   04924 Renin secretion
    155 (ADRB3)
  09154 Digestive system
   04970 Salivary secretion
    155 (ADRB3)
  09159 Environmental adaptation
   04714 Thermogenesis
    155 (ADRB3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    155 (ADRB3)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Adrenaline
    155 (ADRB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx 7TM_GPCR_Srv
Motif
Other DBs
NCBI-GeneID: 155
NCBI-ProteinID: NP_000016
OMIM: 109691
HGNC: 288
Ensembl: ENSG00000188778
Vega: OTTHUMG00000164028
Pharos: P13945(Tclin)
UniProt: P13945 A8KAG8
Position
8p11.23
AA seq 408 aa AA seqDB search
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
NT seq 1227 nt NT seq  +upstreamnt  +downstreamnt
atggctccgtggcctcacgagaacagctctcttgccccatggccggacctccccaccctg
gcgcccaataccgccaacaccagtgggctgccaggggttccgtgggaggcggccctagcc
ggggccctgctggcgctggcggtgctggccaccgtgggaggcaacctgctggtcatcgtg
gccatcgcctggactccgagactccagaccatgaccaacgtgttcgtgacttcgctggcc
gcagccgacctggtgatgggactcctggtggtgccgccggcggccaccttggcgctgact
ggccactggccgttgggcgccactggctgcgagctgtggacctcggtggacgtgctgtgt
gtgaccgccagcatcgaaaccctgtgcgccctggccgtggaccgctacctggctgtgacc
aacccgctgcgttacggcgcactggtcaccaagcgctgcgcccggacagctgtggtcctg
gtgtgggtcgtgtcggccgcggtgtcgtttgcgcccatcatgagccagtggtggcgcgta
ggggccgacgccgaggcgcagcgctgccactccaacccgcgctgctgtgccttcgcctcc
aacatgccctacgtgctgctgtcctcctccgtctccttctaccttcctcttctcgtgatg
ctcttcgtctacgcgcgggttttcgtggtggctacgcgccagctgcgcttgctgcgcggg
gagctgggccgctttccgcccgaggagtctccgccggcgccgtcgcgctctctggccccg
gccccggtggggacgtgcgctccgcccgaaggggtgcccgcctgcggccggcggcccgcg
cgcctcctgcctctccgggaacaccgggccctgtgcaccttgggtctcatcatgggcacc
ttcactctctgctggttgcccttctttctggccaacgtgctgcgcgccctggggggcccc
tctctagtcccgggcccggctttccttgccctgaactggctaggttatgccaattctgcc
ttcaacccgctcatctactgccgcagcccggactttcgcagcgccttccgccgtcttctg
tgccgctgcggccgtcgcctgcctccggagccctgcgccgccgcccgcccggccctcttc
ccctcgggcgttcctgcggcccggagcagcccagcgcagcccaggctttgccaacggctc
gacggggcttcttggggagtttcttag

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