KEGG   Homo sapiens (human): 147111
Entry
147111            CDS       T01001                                 
Symbol
NOTUM, hNOTUM
Name
(RefSeq) notum, palmitoleoyl-protein carboxylesterase
  KO
K19882  O-palmitoleoyl-L-serine hydrolase [EC:3.1.1.98]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04310  Wnt signaling pathway
Network
nt06505  WNT signaling
  Element
N01442  Wnt signaling modulation, Wnt inhibitor
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    147111 (NOTUM)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.98  [Wnt protein] O-palmitoleoyl-L-serine hydrolase
     147111 (NOTUM)
SSDB
Motif
Pfam: PAE
Other DBs
NCBI-GeneID: 147111
NCBI-ProteinID: NP_848588
OMIM: 609847
HGNC: 27106
Ensembl: ENSG00000185269
Pharos: Q6P988(Tbio)
UniProt: Q6P988
Structure
Position
17:complement(81952507..81961187)
AA seq 496 aa
MGRGVRVLLLLSLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAVE
GNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRW
LLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFI
PYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLL
NVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNG
VVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGL
RLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHD
SHKASKTPLKGCPVHLVDSCPWPHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQP
QGLEPSELLGMLSNGS
NT seq 1491 nt   +upstreamnt  +downstreamnt
atgggccgaggggtgcgcgtgctgctgctgctgagcctgctgcactgcgccgggggcagc
gagggcaggaagacctggcggcgccggggtcagcagccgcctcctcccccgcggaccgag
gcggcgccggcggccggacagcccgtggagagcttcccgctggacttcacggccgtggag
ggtaacatggacagcttcatggcgcaagtcaagagcctggcgcagtccctgtacccctgc
tccgcgcagcagctcaacgaggacctgcgcctgcacctcctactcaacacctcggtgacc
tgcaacgacggcagccccgccggctactacctgaaggagtccaggggcagccggcggtgg
ctcctcttcctggaaggcggctggtactgcttcaaccgcgagaactgcgactccagatac
gacaccatgcggcgcctcatgagctcccgggactggccgcgcactcgcacaggcacaggg
atcctgtcctcacagccggaggagaacccctactggtggaacgcaaacatggtcttcatc
ccctactgctccagtgatgtttggagcggggcttcatccaagtctgagaagaacgagtac
gccttcatgggcgccctcatcatccaggaggtggtgcgggagcttctgggcagagggctg
agcggggccaaggtgctgctgctggccgggagcagcgcggggggcaccggggtgctcctg
aatgtggaccgtgtggctgagcagctggagaagctgggctacccagccatccaggtgcga
ggcctggctgactccggctggttcctggacaacaagcagtatcgccacacagactgcgtc
gacacgatcacgtgcgcgcccacggaggccatccgccgtggcatcaggtactggaacggg
gtggtcccggagcgctgccgacgccagttccaggagggcgaggagtggaactgcttcttt
ggctacaaggtctacccgaccctgcgctgccctgtgttcgtggtgcagtggctgtttgac
gaggcacagctgacggtggacaacgtgcacctgacggggcagccggtgcaggagggcctg
cggctgtacatccagaacctcggccgcgagctgcgccacacactcaaggacgtgccggcc
agctttgcccccgcctgcctctcccatgagatcatcatccggagccactggacggatgtc
caggtgaaggggacgtcgctgccccgagcactgcactgctgggacaggagcctccatgac
agccacaaggccagcaagacccccctcaagggctgccccgtccacctggtggacagctgc
ccctggccccactgcaacccctcatgccccaccgtccgagaccagttcacggggcaagag
atgaacgtggcccagttcctcatgcacatgggcttcgacatgcagacggtggcccagccg
cagggactggagcccagtgagctgctggggatgctgagcaacggaagctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PHAROS (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (140)   
   PDB (140)   
Protein domain (1)   
   Pfam (1)   
All databases (188)   

Download RDF
DBGET integrated database retrieval system