KEGG   Homo sapiens (human): 1487
Entry
1487              CDS       T01001                                 
Symbol
CTBP1, BARS, HADDTS
Name
(RefSeq) C-terminal binding protein 1
  KO
K04496  C-terminal binding protein [EC:1.1.1.428]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04310  Wnt signaling pathway
hsa04330  Notch signaling pathway
hsa05200  Pathways in cancer
hsa05220  Chronic myeloid leukemia
Network
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01577  Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
Disease
H01773  4p deletion syndrome
H02619  Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1487 (CTBP1)
   04330 Notch signaling pathway
    1487 (CTBP1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    1487 (CTBP1)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    1487 (CTBP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1487 (CTBP1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.428  4-methylthio 2-oxobutanoate reductase (NADH)
     1487 (CTBP1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Macropinocytosis
   Others
    1487 (CTBP1)
SSDB
Motif
Pfam: 2-Hacid_dh_C 2-Hacid_dh NAD_binding_2 XdhC_C RS_preATP-grasp-like F420_oxidored
Other DBs
NCBI-GeneID: 1487
NCBI-ProteinID: NP_001319
OMIM: 602618
HGNC: 2494
Ensembl: ENSG00000159692
UniProt: Q13363 X5D8Y5
Structure
Position
4:complement(1211445..1250355)
AA seq 440 aa
MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQ
EIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNV
PAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGII
GLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLN
EHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFS
QGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAAT
HWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHA
PSPGQTVKPEADRDHASDQL
NT seq 1323 nt   +upstreamnt  +downstreamnt
atgggcagctcgcacttgctcaacaagggcctgccgcttggcgtccgacctccgatcatg
aacgggcccctgcacccgcggcccctggtggcattgctggatggccgggactgcacagtg
gagatgcccatcctgaaggacgtggccactgtggccttctgcgacgcgcagtccacgcag
gagatccatgagaaggtcctgaacgaggctgtgggggccctgatgtaccacaccatcact
ctcaccagggaggacctggagaagttcaaagccctccgcatcatcgtccggattggcagt
ggttttgacaacatcgacatcaagtcggccggggatttaggcattgccgtctgcaacgtg
cccgcggcgtctgtggaggagacggccgactcgacgctgtgccacatcctgaacctgtac
cggcgggccacctggctgcaccaggcgctgcgggagggcacacgagtccagagcgtcgag
cagatccgcgaggtggcgtccggcgctgccaggatccgcggggagaccttgggcatcatc
ggacttggtcgcgtggggcaggcagtggcgctgcgggccaaggccttcggcttcaacgtg
ctcttctacgacccttacttgtcggatggcgtggagcgggcgctggggctgcagcgtgtc
agcaccctgcaggacctgctcttccacagcgactgcgtgaccctgcactgcggcctcaac
gagcacaaccaccacctcatcaacgacttcaccgtcaagcagatgagacaaggggccttc
ctggtgaacacagcccggggtggcctggtggatgagaaggcgctggcccaggccctgaag
gagggccggatccgcggcgcggccctggatgtgcacgagtcggaacccttcagctttagc
cagggccctctgaaggatgcacccaacctcatctgcaccccccatgctgcatggtacagc
gagcaggcatccatcgagatgcgagaggaggcggcacgggagatccgcagagccatcaca
ggccggatcccagacagcctgaagaactgtgtcaacaaggaccatctgacagccgccacc
cactgggccagcatggaccccgccgtcgtgcaccctgagctcaatggggctgcctatagg
taccctccgggcgtggtgggcgtggcccccactggcatcccagctgctgtggaaggtatc
gtccccagcgccatgtccctgtcccacggcctgccccctgtggcccacccgccccacgcc
ccttctcctggccaaaccgtcaagcccgaggcggatagagaccacgccagtgaccagttg
tag

  All links  
Disease (3)   
   OMIM (3)   
Gene (18)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (15)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (46)   
   RefSeq(nuc) (12)   
   GenBank (17)   
   EMBL (17)   
3D Structure (10)   
   PDB (10)   
Protein domain (6)   
   Pfam (6)   
All databases (98)   

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