KEGG   Homo sapiens (human): 154197
Entry
154197            CDS       T01001                                 
Symbol
PNLDC1, HsPNLDC1, SPGF57, Trimmer
Name
(RefSeq) PARN like ribonuclease domain containing exonuclease 1
  KO
K01148  poly(A)-specific ribonuclease [EC:3.1.13.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Disease
H01282  Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    154197 (PNLDC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    154197 (PNLDC1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.13  Exoribonucleases producing 5'-phosphomonoesters
    3.1.13.4  poly(A)-specific ribonuclease
     154197 (PNLDC1)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Other 3'-5' decay factors
     154197 (PNLDC1)
SSDB
Motif
Pfam: CAF1
Other DBs
NCBI-GeneID: 154197
NCBI-ProteinID: NP_775787
OMIM: 619529
HGNC: 21185
Ensembl: ENSG00000146453
UniProt: Q8NA58
Position
6:159799455..159820704
AA seq 520 aa
MFCTRGLLFFAFLAGLDIEFTGLRSNLSGPQQISLFDLPSEWYLKTRQSVQQFTVCQIGL
SVFSAIEGEANKYIAHSCNFYLFPTTFGILDSEFSFQASSVQFLNQYGFNYNKFLKNGIP
YMNEEQEKKIRHDILTGNWRVRSSPDKDQIKVVIDEVTRWLELAKEGDWMTLPGITGFQA
FEVQLVLRQALPNIWTVLKDEGVVVKKVSKQHRWYLQNTSCDRESCWKENILLSARGFSV
FFQMLVKAQKPLVGHNMMMDLLHLHEKFFRPLPESYDQFKQNIHSLFPVLIDTKSVTKDI
WKEMNFPRVSNLSEVYEVLNSDLNPTKNSGPEIVHASRCEKYVETKCPHEAAYDAFLCGS
VLLKVAHLLLQKIYHIDPVPESSFPQYLDVLAPYVNQVNLIRAGVPKINFSGPDYPSIRP
PILILSVKRWPGVSEQQVYHKFQNLCKFDVRRLTRSQFLLLTNKFKDARNILKEYRDHPT
LCISLYRYWRHSPNVNCLLQVCGIVTAWALLAFILGRSGT
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgttctgcacccgaggactgctattttttgccttcctggcaggtctggacatagagttc
acgggccttcgttctaacctgtctgggccccagcagatcagtctttttgatttgccatcg
gagtggtatctaaagacccgtcagagtgttcagcaatttacagtctgtcagattggattg
tctgtgttttccgctattgaaggagaggcaaacaagtatatagcccattcttgtaacttc
tatctcttccctacaacgtttgggattttggactcagaattctccttccaggcttccagt
gttcagtttttgaatcagtatggcttcaactataacaagtttctcaaaaacggaatccca
tatatgaatgaagaacaggagaagaaaattagacacgatatcctgactgggaactggaga
gttcgcagctctccggataaagaccaaatcaaggtggtgattgacgaagtgacgcggtgg
ctggagctggccaaggaaggcgactggatgactcttcctgggatcactggcttccaggcc
tttgaggtccaactggtgctgaggcaggccctccccaacatctggacggtgctgaaagat
gagggggtggtagtgaagaaagtgagtaaacaacatcgttggtatcttcagaacacctct
tgtgaccgagagagctgttggaaggaaaatattcttctctcagcaaggggtttttctgtc
tttttccaaatgctggtgaaagcccagaagcccttagtgggacataatatgatgatggac
ctgctgcacctccatgagaagttcttcagacccctcccagaaagctacgatcaatttaag
cagaatatccacagcctatttcctgttctcattgataccaagagtgtaacaaaggatatc
tggaaggagatgaatttcccgagggtgtcgaatctttcggaagtctatgaagtcctgaac
agtgacttgaatcccaccaagaattctggaccagagattgttcacgcgagcaggtgtgag
aaatatgttgagacaaagtgcccccacgaagccgcgtatgatgccttcctctgtgggtca
gttcttttgaaagtggcacacttgcttctacagaagatataccacatcgaccccgtgccc
gagtcatcctttcctcagtaccttgacgtgctggctccttacgtgaaccaagtgaacctc
atccgagcgggggtcccaaagatcaatttttctggtccagattatcccagtatccgacct
cccatcctcatcctcagcgtcaaaaggtggcctggggtcagcgagcagcaagtctaccat
aagtttcagaatctctgcaagtttgatgtcaggcgactcacaagaagccagttcttactc
ctgaccaataagtttaaggatgcgcggaacatcctgaaggagtaccgggaccacccgacc
ctgtgcatctccctgtaccgctactggaggcactccccaaacgtcaactgcctgctccaa
gtctgtggcatagtgactgcctgggcccttctcgcgttcatccttggaagatctggtacc
tga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (20)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (26)   
   RefSeq(nuc) (18)   
   GenBank (4)   
   EMBL (4)   
Protein domain (1)   
   Pfam (1)   
All databases (64)   

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