| Entry |
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| Symbol |
CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450
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| Name |
(RefSeq) cytochrome P450 family 2 subfamily B member 6
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| KO |
| K17709 | cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-] |
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| Organism |
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| Pathway |
| hsa00980 | Metabolism of xenobiotics by cytochrome P450 |
| hsa00982 | Drug metabolism - cytochrome P450 |
| hsa05207 | Chemical carcinogenesis - receptor activation |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
1555 (CYP2B6)
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
1555 (CYP2B6)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
1555 (CYP2B6)
00982 Drug metabolism - cytochrome P450
1555 (CYP2B6)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
1555 (CYP2B6)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
1555 (CYP2B6)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:hsa00199]
1555 (CYP2B6)
Enzymes [BR:hsa01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.-
1555 (CYP2B6)
Cytochrome P450 [BR:hsa00199]
Cytochrome P450, animal type
CYP2 family
1555 (CYP2B6)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
19q13.2
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| AA seq |
491 aa
MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFRE
KYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNR
WKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIIC
SIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLKYFPGAHRQVYKNLQE
INAYIGHSVEKHRETLDPSAPKDLIDTYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGT
ETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFS
DLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGAL
KKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKI
PPTYQIRFLPR |
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| NT seq |
1476 nt +upstreamnt +downstreamnt
atggaactcagcgtcctcctcttccttgcactcctcacaggactcttgctactcctggtt
cagcgccaccctaacacccatgaccgcctcccaccagggccccgccctctgccccttttg
ggaaaccttctgcagatggatagaagaggcctactcaaatcctttctgaggttccgagag
aaatatggggacgtcttcacggtacacctgggaccgaggcccgtggtcatgctgtgtgga
gtagaggccatacgggaggcccttgtggacaaggctgaggccttctctggccggggaaaa
atcgccatggtcgacccattcttccggggatatggtgtgatctttgccaatggaaaccgc
tggaaggtgcttcggcgattctctgtgaccactatgagggacttcgggatgggaaagcgg
agtgtggaggagcggattcaggaggaggctcagtgtctgatagaggagcttcggaaatcc
aagggggccctcatggaccccaccttcctcttccagtccattaccgccaacatcatctgc
tccatcgtctttggaaaacgattccactaccaagatcaagagttcctgaagatgctgaac
ttgttctaccagactttttcactcatcagctctgtattcggccagctgtttgagctcttc
tctggcttcttgaaatactttcctggggcacacaggcaagtttacaaaaacctgcaggaa
atcaatgcttacattggccacagtgtggagaagcaccgtgaaaccctggaccccagcgcc
cccaaggacctcatcgacacctacctgctccacatggaaaaagagaaatccaacgcacac
agtgaattcagccaccagaacctcaacctcaacacgctctcgctcttctttgctggcact
gagaccaccagcaccactctccgctacggcttcctgctcatgctcaaataccctcatgtt
gcagagagagtctacagggagattgaacaggtgattggcccacatcgccctccagagctt
catgaccgagccaaaatgccatacacagaggcagtcatctatgagattcagagattttcc
gaccttctccccatgggtgtgccccacattgtcacccaacacaccagcttccgagggtac
atcatccccaaggacacagaagtatttctcatcctgagcactgctctccatgacccacac
tactttgaaaaaccagacgccttcaatcctgaccactttctggatgccaatggggcactg
aaaaagactgaagcttttatccccttctccttagggaagcggatttgtcttggtgaaggc
atcgcccgtgcggaattgttcctcttcttcaccaccatcctccagaacttctccatggcc
agccccgtggccccagaagacatcgatctgacaccccaggagtgtggtgtgggcaaaata
cccccaacataccagatccgcttcctgccccgctga |
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