KEGG   Homo sapiens (human): 1609Help
Entry
1609              CDS       T01001                                 

Gene name
DGKQ, DAGK, DAGK4, DAGK7
Definition
(RefSeq) diacylglycerol kinase theta
  KO
K00901  diacylglycerol kinase (ATP) [EC:2.7.1.107]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
hsa04072  Phospholipase D signaling pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Metabolism
  Lipid metabolism
   00561 Glycerolipid metabolism
    1609 (DGKQ)
   00564 Glycerophospholipid metabolism
    1609 (DGKQ)
 Environmental Information Processing
  Signal transduction
   04070 Phosphatidylinositol signaling system
    1609 (DGKQ)
   04072 Phospholipase D signaling pathway
    1609 (DGKQ)
 Human Diseases
  Cancers
   05231 Choline metabolism in cancer
    1609 (DGKQ)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.107  diacylglycerol kinase (ATP)
     1609 (DGKQ)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DAGK_acc RA C1_1 DAGK_cat C1_2
Motif
Other DBs
NCBI-GeneID: 1609
NCBI-ProteinID: NP_001338
OMIM: 601207
HGNC: 2856
Ensembl: ENSG00000145214
Vega: OTTHUMG00000088629
Pharos: P52824(Tbio)
UniProt: P52824 Q59FF7 A0A140VKC1
Position
4p16.3
AA seq 942 aa AA seqDB search
MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL
KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET
RYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTILLD
AHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYV
RVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEKP
RMDDGLLEVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGH
MIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR
NT seq 2829 nt NT seq  +upstreamnt  +downstreamnt
atggcggcggcggccgagcccggggcccgcgcctggctgggcggcggctccccgcgcccc
ggcagcccggcctgcagccccgtgctgggctcaggaggccgcgcgcgcccggggccgggg
ccggggccgggacccgagcgggcgggcgtcagagccccgggccccgctgccgcgccggga
cacagcttccggaaggtgacgctcaccaagcccaccttctgccacctctgctccgacttc
atctgggggctggccggcttcctgtgcgacgtctgcaatttcatgtctcatgagaagtgc
ctgaagcacgtgaggatcccgtgcacgagtgtggcacccagcctggtccgggttcctgta
gcccactgcttcggcccccgggggctccacaagcgcaagttctgtgctgtctgccgcaag
gtcctggaggcaccggcgctccactgcgaagtgtgtgagctgcacctccacccagactgt
gtgcccttcgcctgcagtgactgccgccagtgccaccaggatgggcaccaggatcacgac
acccatcaccaccactggcgggaggggaacctgccctcgggagcgcgctgcgaggtctgc
aggaagacgtgcggctcctctgacgtgctggccggcgtgcgctgcgagtggtgcggggtc
caggcgcactccctctgctccgcggcgctggctcccgagtgtggcttcgggcgtctgcgc
tccctggtcctgcctcccgcgtgcgtgcgccttctgcccggcggcttcagcaagacgcag
agcttccgcatcgtggaggccgcggagccgggcgaggggggcgacggcgccgacgggagc
gctgccgtgggtccaggcagagagacacaggcaactccggagtccgggaagcaaacgctg
aagatctttgatggcgacgacgcggtgagaagaagccagttccgcctcgtcacggtgtcc
cgcctggccggtgccgaggaggtgctggaggccgcactgcgggcccaccacatccccgag
gaccctggccacctggagctgtgccggctgcccccttcctctcaggcctgtgacgcctgg
gctgggggcaaggctgggagtgctgtgatctcggaggagggcagaagccccgggtccggc
gaggccacgccagaggcctgggtcatccgggctctgccgcgggcccaggaggtcctgaag
atctaccctggctggctcaaggtgggcgtggcctacgtgtccgtgcgagtgaccccgaag
agcacggcccgctctgtggtgctggaggtcctgccgctgctcggccgccaggccgagagt
cccgagagcttccagctggtggaggtggcgatgggctgcaggcacgtccagcggacgatg
ctgatggacgaacagcccctgctggaccggctacaggacatccggcagatgtctgtgcgg
caggtgagccagacgcggttctacgtggcagagagcagggatgtagccccgcacgtctcc
ctgtttgttggcggcctgcctcccggcctgtctcccgaggagtacagcagcctgctgcat
gaggccggggctaccaaagccaccgtggtgtccgtgagtcacatctactcctcccaaggc
gcggtagtgttggacgttgcctgctttgcggaggccgagcggctgtacatgctgctgaag
gacatggctgtgcggggccggctgctcactgccctggtgctccccgacctgctgcacgcg
aagctgcccccagacagctgtcccctccttgtgttcgtgaaccccaagagtggaggcctc
aagggccgagacctgctctgcagcttccggaagctactgaaccctcatcaggtcttcgac
ctgaccaacggaggtcctcttcccgggctccacctgttctcccaggtgccctgcttccgg
gtgctggtgtgtggtggcgatggcactgtgggctgggtgcttggcgccctggaggagaca
cggtaccgactggcctgcccggagccttctgtggccatcctgcccctgggcacagggaat
gaccttggtcgagtcctccgctggggggcgggctacagcggcgaggacccgttctccgta
ctgctgtctgtggacgaggccgacgccgtgctcatggaccgctggaccatcctgctggat
gcccacgaggctggcagtgcagagaacgacacggcagacgcagagccccccaagatcgtg
cagatgagtaactactgtggcattggcatcgacgcggagctgagcctggacttccaccag
gcacgggaagaggagcctggcaagttcacaagcaggctgcacaacaagggtgtgtacgtg
cgggtggggctgcagaagatcagtcactctcggagcctgcacaagcagatccggctgcag
gtggagcggcaggaggtggagctgcccagtattgaaggcctcatcttcatcaacatcccc
agctggggctcgggggccgacctgtggggctccgacagcgacaccaggtttgagaagcca
cgcatggacgacgggctgctggaggttgtgggcgtgacgggcgtcgtgcacatgggccag
gtccagggtgggctgcgctccggaatccggattgcccagggttcctacttccgagtcacg
ctcctcaaggccaccccggtgcaggtggacggggagccctgggtccaggccccggggcac
atgatcatctcagctgctggccctaaggtgcacatgctgaggaaggccaagcagaagccg
aggagggccgggaccaccagggatgcccgggcggatgctgcgcctgcccctgagagcgat
cctaggtag

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