KEGG   Homo sapiens (human): 161Help
Entry
161               CDS       T01001                                 

Gene name
AP2A2, ADTAB, CLAPA2, HIP-9, HIP9, HYPJ
Definition
(RefSeq) adaptor related protein complex 2 subunit alpha 2
  KO
K11824  AP-2 complex subunit alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04721  Synaptic vesicle cycle
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    161 (AP2A2)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    161 (AP2A2)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    161 (AP2A2)
 09160 Human Diseases
  09164 Neurodegenerative diseases
   05016 Huntington disease
    161 (AP2A2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    161 (AP2A2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    161 (AP2A2)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   AP-2 complex
    161 (AP2A2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   161 (AP2A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Adaptin_N Alpha_adaptin_C Alpha_adaptinC2 Cnd1 HEAT_2 DRIM RIX1 Dymeclin
Motif
Other DBs
NCBI-GeneID: 161
NCBI-ProteinID: NP_036437
OMIM: 607242
HGNC: 562
Ensembl: ENSG00000183020
Vega: OTTHUMG00000165627
Pharos: O94973(Tbio)
UniProt: O94973
Position
11p15.5
AA seq 939 aa AA seqDB search
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
ASRNPTFMGLALHCIASVGSREMAEAFAGEIPKVLVAGDTMDSVKQSAALCLLRLYRTSP
DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQ
HSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEF
SHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIR
EEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAK
TVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRALL
LSTYIKFVNLFPEVKPTIQDVLRSDSQLRNADVELQQRAVEYLRLSTVASTDILATVLEE
MPPFPERESSILAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAVSTPSPSAD
LLGLGAAPPAPAGPPPSSGGSGLLVDVFSDSASVVAPLAPGSEDNFARFVCKNNGVLFEN
QLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQPNLNLQTKPVDPTVEG
GAQVQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVQLPITLNKFFQPTEMASQDFFQR
WKQLSNPQQEVQNIFKAKHPMDTEVTKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQ
IGCLLRLEPNLQAQMYRLTLRTSKEAVSQRLCELLSAQF
NT seq 2820 nt NT seq  +upstreamnt  +downstreamnt
atgccggccgtgtccaagggggacgggatgcggggcctggcggtcttcatctcggatatc
cgcaactgtaaaagtaaagaagcagaaataaaaaggataaacaaggaactggcaaatatc
agatcaaaatttaaaggtgacaaggctcttgatggctatagtaaaaaaaagtacgtctgc
aagttgctcttcatctttctccttggtcatgacattgactttggacacatggaggctgtg
aacctgctgagttcaaacagatacacggaaaagcagatcggctaccttttcatctctgtg
ttggtgaactcaaacagtgagctgatccgcctgatcaacaacgccatcaagaatgacctg
gccagccgcaaccccaccttcatgggcctggccctgcactgcatcgccagcgtgggcagc
cgggagatggccgaggccttcgccggggagatccctaaggtcctcgtagccggagacact
atggacagcgtgaagcagagcgcggccctgtgcttgctgcgcctgtacaggacgtccccc
gatcttgtccccatgggcgactggacatcccgagtggtgcacctgctcaatgaccagcac
ttgggtgtggtaactgcagccacaagtctgatcaccactttagcacagaagaacccagaa
gagtttaaaacctccgtgtctctggctgtctctaggctaagcagaatcgtgacgtctgca
tccacagatctccaggattacacttactattttgtcccggctccctggctgtctgtcaaa
ctgctgagactgctgcagtgctacccacccccagaccctgcagtgcgaggccgcctgact
gagtgcctggagaccatcctgaacaaagcccaagaaccgcccaagtcgaagaaggtccag
cactccaacgcgaagaatgccgtgctcttcgaggccatcagcttaatcattcaccatgac
agtgagccgaacctgctcgtccgtgcctgcaaccagttgggccagtttctgcagcaccgc
gagaccaacctgcgctacctggccctggagagcatgtgcacgctggccagctctgagttc
tcccatgaggctgtcaagacgcacatcgagacggtcatcaacgccctgaagactgagcgg
gacgtgagcgtgcggcagcgggccgtggacctcctctacgccatgtgcgaccgcagcaac
gccccacagatcgtggccgagatgctgagctatctggagacagctgactactccatccga
gaagagattgtgctgaaggtcgccatcctggctgagaagtacgcggtggactacacctgg
tatgtggataccatcttgaacttgatccgaattgctggtgattacgtgagtgaagaggtg
tggtaccgagtcattcagatcgtcatcaaccgggacgacgtgcagggctacgcggccaag
actgtgttcgaggctcttcaggctcccgcgtgccacgagaacctggtcaaagtgggcggc
tacatcctgggggagtttggaaacttgatagctggagacccgagatccagcccgctgatc
cagttccacctgctgcactccaagttccacctgtgcagcgtccccacccgcgcgctgctc
ctgtccacctacatcaagttcgtgaacctcttcccggaggtgaagcccaccatccaggac
gtgctgcgcagcgacagccagctcaggaacgcagacgtggagctgcagcagcgtgctgtg
gagtacctgcggctcagcaccgtggccagcaccgacattctggcgaccgtgctggaggag
atgcccccattcccggagcgggagtcctccatcttggcaaagctcaagaagaagaagggc
cccagcacggtgacagacctggaggacaccaagcgggacaggagtgtggacgtgaacggg
ggtcctgagcctgccccagccagtaccagcgccgtgtctacgccttctccgtcggcagac
ctgctgggtctcggggctgccccccctgcccccgcgggccccccaccctcctccggcggc
agcgggctgctcgtggacgtgttctcagactcggcctctgtggtcgcgcctctcgctcct
ggctccgaagacaactttgccaggtttgtttgtaaaaacaatggtgtgttgtttgaaaac
cagctgcttcaaattggacttaagtctgaatttcggcagaatttaggtcggatgtttatc
ttttatggtaataagacctccacgcagttcctaaactttaccccaacactaatctgttca
gacgaccttcagcctaacctgaacctgcagaccaagcccgtggacccgaccgtggagggg
ggcgcgcaggtgcagcaggtggtcaacatagagtgcgtgtccgacttcacggaggcgcca
gtcctcaacattcagttcaggtatgggggcaccttccagaacgtgtctgtgcagctgccc
atcactctcaacaaattcttccagccgacagaaatggcttctcaggatttctttcaacgt
tggaagcagttgagcaatccacagcaggaagtgcagaacatcttcaaagcaaagcaccca
atggacacagaagtcaccaaagccaagatcattggatttggttctgcacttcttgaagaa
gttgatcctaatcctgcgaatttcgtgggagctggaatcatccacacgaaaaccacccag
attggatgcctgctgcgcttggagccgaacctgcaagcccagatgtaccggctcacgctg
cgcacaagtaaggaagccgtttctcagagattatgtgaattgctctcagcgcagttttag

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