KEGG   Homo sapiens (human): 161742
Entry
161742            CDS       T01001                                 
Symbol
SPRED1, LGSS, NFLS, PPP1R147, hSpred1, spred-1
Name
(RefSeq) sprouty related EVH1 domain containing 1
  KO
K04703  sprouty-related, EVH1 domain-containing protein
Organism
hsa  Homo sapiens (human)
Network
nt06526  MAPK signaling
  Element
N01597  Regulation of GF-RTK-RAS-ERK signaling, SPRED and NF1
Disease
H01986  Legius syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    161742 (SPRED1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     161742 (SPRED1)
SSDB
Motif
Pfam: Sprouty WH1 SMC_ScpA
Other DBs
NCBI-GeneID: 161742
NCBI-ProteinID: NP_689807
OMIM: 609291
HGNC: 20249
Ensembl: ENSG00000166068
UniProt: Q7Z699
Structure
Position
15:38252836..38357249
AA seq 444 aa
MSEETATSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTVFKVPHQEENGCADFFI
RGERLRDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAI
EDISQGCPESKNEAEGADDLQANEEDSSSSLVKDHLFQQETVVTSEPYRSSNIRPSPFED
LNARRVYMQSQANQITFGQPGLDIQSRSMEYVQRQISKECGSLKSQNRVPLKSIRHVSFQ
DEDEIVRINPRDILIRRYADYRHPDMWKNDLERDDADSSIQFSKPDSKKSDYLYSCGDET
KLSSPKDSVVFKTQPSSLKIKKSKRRKEDGERSRCVYCQERFNHEENVRGKCQDAPDPIK
RCIYQVSCMLCAESMLYHCMSDSEGDFSDPCSCDTSDDKFCLRWLALVALSFIVPCMCCY
VPLRMCHRCGEACGCCGGKHKAAG
NT seq 1335 nt   +upstreamnt  +downstreamnt
atgagcgaggagacggcgacttctgacaacgataatagttatgcacgagtgcgagctgtg
gtgatgacccgagatgactcaagtggtggatggttaccacttggagggagtggactaagc
agcgtcactgtcttcaaagtccctcatcaggaagagaatggctgtgctgacttttttatc
cgtggagagcgactcagggacaaaatggtggttttggaatgtatgcttaaaaaagacctc
atttataataaggtcactccaacatttcaccactggaagattgatgacaagaagtttggt
cttacgtttcaaagtcctgctgatgctagggcttttgatagaggtatccgaagagctata
gaggatatttctcaaggatgccccgaatcaaaaaatgaagctgaaggggcagatgactta
caagcaaatgaagaggattcttccagttctctagtgaaggatcacctttttcagcaagag
acagttgttaccagtgagccttatagaagctcaaatataagaccttctccctttgaagat
ctgaatgccagaagagtctacatgcaaagccaagccaatcagataacatttggtcagcca
ggcttggacattcagagcagaagtatggaatacgtacagcggcaaatatccaaggaatgt
ggaagcctaaagtcccaaaatagggtccctttgaaatcaatcagacatgtcagctttcaa
gatgaggatgagattgtcagaataaaccctcgagatatcttaatacgtcgctatgcagac
tacagacatcctgacatgtggaaaaatgacttggaaagagatgatgctgattccagtatt
cagttttctaaaccagacagtaaaaaatcagactatctgtactcttgtggggatgagact
aagttaagttcacccaaagactctgtggtatttaagacgcagccttcctcattaaaaatt
aagaagtcaaaacgaagaaaagaggatggtgaacgttctcgctgcgtatactgccaggaa
aggtttaatcatgaagaaaatgttaggggaaaatgtcaggatgctccagaccctattaaa
agatgcatatatcaagttagttgcatgctctgtgcagagagcatgttgtatcattgtatg
tcagactcagagggagatttttctgatccctgttcgtgtgacactagcgacgacaagttc
tgcttgcgatggttagccctggtagctttgtctttcattgtaccatgtatgtgctgctac
gtccctttgagaatgtgccatcgctgtggtgaggcatgtggttgctgtggtgggaaacat
aaagctgctggatga

  All links  
Disease (2)   
   OMIM (2)   
Gene (11)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (24)   
   RefSeq(nuc) (8)   
   GenBank (8)   
   EMBL (8)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (53)   

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