KEGG   Homo sapiens (human): 163688Help
Entry
163688            CDS       T01001                                 

Gene name
CALML6, CAGLP
Definition
(RefSeq) calmodulin like 6
  KO
K02183  calmodulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04020  Calcium signaling pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04070  Phosphatidylinositol signaling system
hsa04114  Oocyte meiosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04371  Apelin signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04713  Circadian entrainment
hsa04720  Long-term potentiation
hsa04722  Neurotrophin signaling pathway
hsa04728  Dopaminergic synapse
hsa04740  Olfactory transduction
hsa04744  Phototransduction
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04910  Insulin signaling pathway
hsa04912  GnRH signaling pathway
hsa04915  Estrogen signaling pathway
hsa04916  Melanogenesis
hsa04921  Oxytocin signaling pathway
hsa04922  Glucagon signaling pathway
hsa04924  Renin secretion
hsa04925  Aldosterone synthesis and secretion
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa05010  Alzheimer's disease
hsa05031  Amphetamine addiction
hsa05034  Alcoholism
hsa05133  Pertussis
hsa05152  Tuberculosis
hsa05167  Kaposi's sarcoma-associated herpesvirus infection
hsa05200  Pathways in cancer
hsa05214  Glioma
hsa05418  Fluid shear stress and atherosclerosis
Drug target
Lubeluzole: D04789
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    163688 (CALML6)
   04015 Rap1 signaling pathway
    163688 (CALML6)
   04371 Apelin signaling pathway
    163688 (CALML6)
   04020 Calcium signaling pathway
    163688 (CALML6)
   04070 Phosphatidylinositol signaling system
    163688 (CALML6)
   04024 cAMP signaling pathway
    163688 (CALML6)
   04022 cGMP - PKG signaling pathway
    163688 (CALML6)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    163688 (CALML6)
   04218 Cellular senescence
    163688 (CALML6)
 Organismal Systems
  Immune system
   04625 C-type lectin receptor signaling pathway
    163688 (CALML6)
  Endocrine system
   04910 Insulin signaling pathway
    163688 (CALML6)
   04922 Glucagon signaling pathway
    163688 (CALML6)
   04912 GnRH signaling pathway
    163688 (CALML6)
   04915 Estrogen signaling pathway
    163688 (CALML6)
   04921 Oxytocin signaling pathway
    163688 (CALML6)
   04916 Melanogenesis
    163688 (CALML6)
   04924 Renin secretion
    163688 (CALML6)
   04925 Aldosterone synthesis and secretion
    163688 (CALML6)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    163688 (CALML6)
   04270 Vascular smooth muscle contraction
    163688 (CALML6)
  Digestive system
   04970 Salivary secretion
    163688 (CALML6)
   04971 Gastric acid secretion
    163688 (CALML6)
  Nervous system
   04728 Dopaminergic synapse
    163688 (CALML6)
   04720 Long-term potentiation
    163688 (CALML6)
   04722 Neurotrophin signaling pathway
    163688 (CALML6)
  Sensory system
   04744 Phototransduction
    163688 (CALML6)
   04740 Olfactory transduction
    163688 (CALML6)
   04750 Inflammatory mediator regulation of TRP channels
    163688 (CALML6)
  Environmental adaptation
   04713 Circadian entrainment
    163688 (CALML6)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    163688 (CALML6)
   05214 Glioma
    163688 (CALML6)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    163688 (CALML6)
  Substance dependence
   05031 Amphetamine addiction
    163688 (CALML6)
   05034 Alcoholism
    163688 (CALML6)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    163688 (CALML6)
  Infectious diseases
   05133 Pertussis
    163688 (CALML6)
   05152 Tuberculosis
    163688 (CALML6)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    163688 (CALML6)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     163688 (CALML6)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    163688 (CALML6)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Centriole replication proteins
     163688 (CALML6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   163688 (CALML6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 EF-hand_9 EF-hand_5 EF-hand_4
Motif
Other DBs
NCBI-GeneID: 163688
NCBI-ProteinID: NP_619650
OMIM: 610171
HGNC: 24193
Ensembl: ENSG00000169885
Vega: OTTHUMG00000000943
Pharos: Q8TD86(Tdark)
UniProt: Q8TD86
Position
1p36.33
AA seq 181 aa AA seqDB search
MGLQQEISLQPWCHHPAESCQTTTDMTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEW
LMSLLGINPTKSELASMAKDVDRDNKGFFNCDGFLALMGVYHEKAQNQESELRAAFRVFD
KEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMMKEADKDGDRTIDYEEFVAMMTGESFKLI
Q
NT seq 546 nt NT seq  +upstreamnt  +downstreamnt
atgggtcttcaacaagaaatctcactgcagccctggtgtcaccaccctgcagaatcctgt
cagacaaccaccgacatgacagagcgcctgtcggctgagcagatcaaggagtacaaggga
gtctttgagatgttcgacgaagagggcaacggggaggtgaagacgggggagctggagtgg
ctcatgagcctgctgggtatcaaccccaccaagagtgagctggcctcaatggccaaggat
gtggacagagacaacaaagggttcttcaactgcgatggtttcctggcactaatgggagtt
taccatgagaaggcccagaaccaggagagcgagctgagggcggcattccgtgtctttgac
aaagagggcaagggctacattgactggaacacactcaagtacgtgctaatgaacgcaggg
gagcccctcaacgaggtggaggcggagcagatgatgaaggaggccgacaaggatggggac
aggaccatcgactatgaggagtttgtggccatgatgacgggggagtccttcaagctgatc
cagtag

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