KEGG   Homo sapiens (human): 163702
Entry
163702            CDS       T01001                                 
Symbol
IFNLR1, CRF2/12, IFNLR, IL-28R1, IL28RA, LICR2
Name
(RefSeq) interferon lambda receptor 1
  KO
K05140  interferon lambda receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
Drug target
Peginterferon lambda-1a: D10078
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    163702 (IFNLR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    163702 (IFNLR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:hsa04050]
    163702 (IFNLR1)
Cytokine receptors [BR:hsa04050]
 Interleukin receptor families
  IL10/28 receptor family
   163702 (IFNLR1)
SSDB
Motif
Pfam: Tissue_fac
Other DBs
NCBI-GeneID: 163702
NCBI-ProteinID: NP_734464
OMIM: 607404
HGNC: 18584
Ensembl: ENSG00000185436
UniProt: Q8IU57
Structure
Position
1:complement(24154168..24187289)
AA seq 520 aa
MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
SSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYL
FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQ
PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLL
VIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLCPQKELTR
GVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQEHQAPGHS
EAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPGQGPGGDG
HQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLTFCWESSP
EEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
NT seq 1563 nt   +upstreamnt  +downstreamnt
atggcggggcccgagcgctggggccccctgctcctgtgcctgctgcaggccgctccaggg
aggccccgtctggcccctccccagaatgtgacgctgctctcccagaacttcagcgtgtac
ctgacatggctcccagggcttggcaacccccaggatgtgacctattttgtggcctatcag
agctctcccacccgtagacggtggcgcgaagtggaagagtgtgcgggaaccaaggagctg
ctatgttctatgatgtgcctgaagaaacaggacctgtacaacaagttcaagggacgcgtg
cggacggtttctcccagctccaagtccccctgggtggagtccgaatacctggattacctt
tttgaagtggagccggccccacctgtcctggtgctcacccagacggaggagatcctgagt
gccaatgccacgtaccagctgcccccctgcatgcccccactggatctgaagtatgaggtg
gcattctggaaggagggggccggaaacaagaccctatttccagtcactccccatggccag
ccagtccagatcactctccagccagctgccagcgaacaccactgcctcagtgccagaacc
atctacacgttcagtgtcccgaaatacagcaagttctctaagcccacctgcttcttgctg
gaggtcccagaagccaactgggctttcctggtgctgccatcgcttctgatactgctgtta
gtaattgccgcagggggtgtgatctggaagaccctcatggggaacccctggtttcagcgg
gcaaagatgccacgggccctggacttttctggacacacacaccctgtggcaacctttcag
cccagcagaccagagtccgtgaatgacttgttcctctgtccccaaaaggaactgaccaga
ggggtcaggccgacgcctcgagtcagggccccagccacccaacagacaagatggaagaag
gaccttgcagaggacgaagaggaggaggatgaggaggacacagaagatggcgtcagcttc
cagccctacattgaaccaccttctttcctggggcaagagcaccaggctccagggcactcg
gaggctggtggggtggactcagggaggcccagggctcctctggtcccaagcgaaggctcc
tctgcttgggattcttcagacagaagctgggccagcactgtggactcctcctgggacagg
gctgggtcctctggctatttggctgagaaggggccaggccaagggccgggtggggatggg
caccaagaatctctcccaccacctgaattctccaaggactcgggtttcctggaagagctc
ccagaagataacctctcctcctgggccacctggggcaccttaccaccggagccgaatctg
gtccctgggggacccccagtttctcttcagacactgaccttctgctgggaaagcagccct
gaggaggaagaggaggcgagggaatcagaaattgaggacagcgatgcgggcagctggggg
gctgagagcacccagaggaccgaggacaggggccggacattggggcattacatggccagg
tga

  All links  
Disease (1)   
   OMIM (1)   
Gene (20)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (36)   
   RefSeq(nuc) (8)   
   GenBank (14)   
   EMBL (14)   
3D Structure (8)   
   PDB (8)   
Protein domain (1)   
   Pfam (1)   
All databases (76)   

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