KEGG   Homo sapiens (human): 1638
Entry
1638              CDS       T01001                                 

Gene name
DCT, TRP-2, TYRP2
Definition
(RefSeq) dopachrome tautomerase
  KO
K01827  dopachrome tautomerase [EC:5.3.3.12]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00350  Tyrosine metabolism
hsa01100  Metabolic pathways
hsa04916  Melanogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    1638 (DCT)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    1638 (DCT)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.12  L-dopachrome isomerase
     1638 (DCT)
SSDB
Motif
Pfam: Tyrosinase PetG PsbH
Other DBs
NCBI-GeneID: 1638
NCBI-ProteinID: NP_001913
OMIM: 191275
HGNC: 2709
Ensembl: ENSG00000080166
Vega: OTTHUMG00000017206
Pharos: P40126(Tbio)
UniProt: P40126
Position
13q32.1
AA seq 519 aa
MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQ
CTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER
KKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCS
VYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESF
ALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCN
GTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGT
LDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQE
LAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTL
VALVGLFVLLAFLQYRRLRKGYTPLMETHLSSKRYTEEA
NT seq 1560 nt   +upstreamnt  +downstreamnt
atgagccccctttggtgggggtttctgctcagttgcttgggctgcaaaatcctgccagga
gcccagggtcagttcccccgagtctgcatgacggtggacagcctagtgaacaaggagtgc
tgcccacgcctgggtgcagagtcggccaatgtctgtggctctcagcaaggccgggggcag
tgcacagaggtgcgagccgacacaaggccctggagtggtccctacatcctacgaaaccag
gatgaccgtgagctgtggccaagaaaattcttccaccggacctgcaagtgcacaggaaac
tttgccggctataattgtggagactgcaagtttggctggaccggtcccaactgcgagcgg
aagaaaccaccagtgattcggcagaacatccattccttgagtcctcaggaaagagagcag
ttcttgggcgccttagatctcgcgaagaagagagtacaccccgactacgtgatcaccaca
caacactggctgggcctgcttgggcccaatggaacccagccgcagtttgccaactgcagt
gtttatgatttttttgtgtggctccattattattctgttagagatacattattaggacca
ggacgcccctacagggccatagatttctcacatcaaggacctgcatttgttacctggcac
cggtaccatttgttgtgtctggaaagagatctccagcgactcattggcaatgagtctttt
gctttgccctactggaactttgccactgggaggaacgagtgtgatgtgtgtacagaccag
ctgtttggggcagcgagaccagacgatccgactctgattagtcggaactcaagattctcc
agctgggaaactgtctgtgatagcttggatgactacaaccacctggtcaccttgtgcaat
ggaacctatgaaggtttgctgagaagaaatcaaatgggaagaaacagcatgaaattgcca
accttaaaagacatacgagattgcctgtctctccagaagtttgacaatcctcccttcttc
cagaactctaccttcagtttcaggaatgctttggaagggtttgataaagcagatgggact
ctggattctcaagtgatgagccttcataatttggttcattccttcctgaacgggacaaac
gctttgccacattcagccgccaatgatcccatttttgtggttcttcattcctttactgat
gccatctttgatgagtggatgaaaagatttaatcctcctgcagatgcctggcctcaggag
ctggcccctattggtcacaatcggatgtacaacatggttcctttcttccctccagtgact
aatgaagaactctttttaacctcagaccaacttggctacagctatgccatcgatctgcca
gtttcagttgaagaaactccaggttggcccacaactctcttagtagtcatgggaacactg
gtggctttggttggtctttttgtgctgttggcttttcttcaatatagaagacttcgaaaa
ggatatacacccctaatggagacacatttaagcagcaagagatacacagaagaagcctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (35)   
   RefSeq(nuc) (11)   
   GenBank (12)   
   EMBL (12)   
Protein domain (3)   
   Pfam (3)   
All databases (94)   

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