| Entry |
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| Gene name |
DDX3X, CAP-Rf, DBX, DDX14, DDX3, HLP2, MRX102, MRXSSB
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| Definition |
(RefSeq) DEAD-box helicase 3 X-linked
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| KO |
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| Organism |
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| Pathway |
| hsa04622 | RIG-I-like receptor signaling pathway |
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| Network |
nt06121 TLR signaling (viruses and bacteria) nt06162 Hepatitis B virus (HBV) nt06263 Hepatocellular carcinoma |
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| Element |
| N00552 | HBV pol to TLR3-IRF3 signaling pathway |
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| Disease |
| H00480 | X-linked mental retardation |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09151 Immune system
04622 RIG-I-like receptor signaling pathway
1654 (DDX3X)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
1654 (DDX3X)
09172 Infectious disease: viral
05161 Hepatitis B
1654 (DDX3X)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:hsa03019]
1654 (DDX3X)
03041 Spliceosome [BR:hsa03041]
1654 (DDX3X)
03036 Chromosome and associated proteins [BR:hsa03036]
1654 (DDX3X)
Enzymes [BR:hsa01000]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.13 RNA helicase
1654 (DDX3X)
Messenger RNA biogenesis [BR:hsa03019]
Eukaryotic type
mRNA surveillance and transport factors
Transport factors
eIF4F and regulatory proteins
1654 (DDX3X)
mRNA cycle factors
Common to processing body (P body) and stress granule
1654 (DDX3X)
Spliceosome [BR:hsa03041]
Other splicing related proteins
Spliceosome associated proteins (SAPs)
RNA helicase-like proteins
1654 (DDX3X)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
Gene silencing
RISC (RNA-induced silencing complex)
1654 (DDX3X)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
Xp11.4
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| AA seq |
662 aa
MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW
SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE
RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE
SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS
QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV
YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ
IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV
WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR
EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL
ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR
DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW
GN |
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| NT seq |
1989 nt +upstreamnt +downstreamnt
atgagtcatgtggcagtggaaaatgcgctcgggctggaccagcagtttgctggcctagac
ctgaactcttcagataatcagagtggaggaagtacagccagcaaagggcgctatattcct
cctcatttaaggaaccgagaagctactaaaggtttctacgataaagacagttcagggtgg
agttctagcaaagataaggatgcgtatagcagttttggatctcgtagtgattcaagaggg
aagtctagcttcttcagtgatcgtggaagtggatcaaggggaaggtttgatgatcgtgga
cggagtgattacgatggcattggcagccgtggtgacagaagtggctttggcaaatttgaa
cgtggtggaaacagtcgctggtgtgacaaatcagatgaagatgattggtcaaaaccactc
ccaccaagtgaacgcttggaacaggaactcttttctggaggcaacactgggattaatttt
gagaaatacgatgacattccagttgaggcaacaggcaacaactgtcctccacatattgaa
agtttcagtgatgttgagatgggagaaattatcatgggaaacattgagcttactcgttat
actcgcccaactccagtgcaaaagcatgctattcctattatcaaagagaaaagagacttg
atggcttgtgcccaaacagggtctggaaaaactgcagcatttctgttgcccatcttgagt
cagatttattcagatggtccaggcgaggctttgagggccatgaaggaaaatggaaggtat
gggcgccgcaaacaatacccaatctccttggtattagcaccaacgagagagttggcagta
cagatctacgaggaagccagaaaattttcataccgatctagagttcgtccttgcgtggtt
tatggtggtgccgatattggtcagcagattcgagacttggaacgtggatgccatttgtta
gtagccactccaggacgtctagtggatatgatggaaagaggaaagattggattagacttt
tgcaaatacttggtgttagatgaagctgatcggatgttggatatggggtttgagcctcag
attcgtagaatagtcgaacaagatactatgcctccaaagggtgtccgccacactatgatg
tttagtgctacttttcctaaggaaatacagatgctggctcgtgatttcttagatgaatat
atcttcttggctgtaggaagagttggctctacctctgaaaacatcacacagaaagtagtt
tgggtggaagaatcagacaaacggtcatttctgcttgacctcctaaatgcaacaggcaag
gattcactgaccttagtgtttgtggagaccaaaaagggtgcagattctctggaggatttc
ttataccatgaaggatacgcatgtaccagcatccatggagaccgttctcagagggataga
gaagaggcccttcaccagttccgctcaggaaaaagcccaattttagtggctacagcagta
gcagcaagaggactggacatttcaaatgtgaaacatgttatcaattttgacttgccaagt
gatattgaagaatatgtacatcgtattggtcgtacgggacgtgtaggaaaccttggcctg
gcaacctcattctttaacgagaggaacataaatattactaaggatttgttggatcttctt
gttgaagctaaacaagaagtgccgtcttggttagaaaacatggcttatgaacaccactac
aagggtagcagtcgtggacgttctaagagtagcagatttagtggagggtttggtgccaga
gactaccgacaaagtagcggtgccagcagttccagcttcagcagcagccgcgcaagcagc
agccgcagtggcggaggtggccacggtagcagcagaggatttggtggaggtggctatgga
ggcttttacaacagtgatggatatggaggaaattataactcccagggggttgactggtgg
ggtaactga |
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