KEGG   Homo sapiens (human): 1773Help
Entry
1773              CDS       T01001                                 

Gene name
DNASE1, DNL1, DRNI
Definition
(RefSeq) deoxyribonuclease 1
  KO
K11994  deoxyribonuclease-1 [EC:3.1.21.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    1773 (DNASE1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.21  Endodeoxyribonucleases producing 5'-phosphomonoesters
    3.1.21.1  deoxyribonuclease I
     1773 (DNASE1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Exo_endo_phos
Motif
Other DBs
NCBI-GeneID: 1773
NCBI-ProteinID: NP_005214
OMIM: 125505
HGNC: 2956
Ensembl: ENSG00000213918
Vega: OTTHUMG00000129426
Pharos: P24855(Tchem)
UniProt: P24855
Structure
PDB: 

Position
16p13.3
AA seq 282 aa AA seqDB search
MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
EVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYD
DGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKW
GLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAG
MLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
NT seq 849 nt NT seq  +upstreamnt  +downstreamnt
atgaggggcatgaagctgctgggggcgctgctggcactggcggccctactgcagggggcc
gtgtccctgaagatcgcagccttcaacatccagacatttggggagaccaagatgtccaat
gccaccctcgtcagctacattgtgcagatcctgagccgctatgacatcgccctggtccag
gaggtcagagacagccacctgactgccgtggggaagctgctggacaacctcaatcaggat
gcaccagacacctatcactacgtggtcagtgagccactgggacggaacagctataaggag
cgctacctgttcgtgtacaggcctgaccaggtgtctgcggtggacagctactactacgat
gatggctgcgagccctgcgggaacgacaccttcaaccgagagccagccattgtcaggttc
ttctcccggttcacagaggtcagggagtttgccattgttcccctgcatgcggccccgggg
gacgcagtagccgagatcgacgctctctatgacgtctacctggatgtccaagagaaatgg
ggcttggaggacgtcatgttgatgggcgacttcaatgcgggctgcagctatgtgagaccc
tcccagtggtcatccatccgcctgtggacaagccccaccttccagtggctgatccccgac
agcgctgacaccacagctacacccacgcactgtgcctatgacaggatcgtggttgcaggg
atgctgctccgaggcgccgttgttcccgactcggctcttccctttaacttccaggctgcc
tatggcctgagtgaccaactggcccaagccatcagtgaccactatccagtggaggtgatg
ctgaagtga

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