KEGG   Homo sapiens (human): 1830
Entry
1830              CDS       T01001                                 
Symbol
DSG3, ABOLM, CDHF6, PVA
Name
(RefSeq) desmoglein 3
  KO
K07598  desmoglein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04382  Cornified envelope formation
Network
nt06545  Cornified envelope formation
  Element
N01922  Localization of envoplakin and periplakin to the plasma membrane (PM)
Disease
H02648  Acantholytic blistering of the oral and laryngeal mucosa
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    1830 (DSG3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    1830 (DSG3)
Cell adhesion molecules [BR:hsa04515]
 Cadherins
  Major cadherins
   1830 (DSG3)
SSDB
Motif
Pfam: Cadherin CADH_Y-type_LIR
Other DBs
NCBI-GeneID: 1830
NCBI-ProteinID: NP_001935
OMIM: 169615
HGNC: 3050
Ensembl: ENSG00000134757
UniProt: P32926
Structure
Position
18:31447741..31478702
AA seq 999 aa
MMGLFPRTTGALAIFVVVILVHGELRIETKGQYDEEEMTMQQAKRRQKREWVKFAKPCRE
GEDNSKRNPIAKITSDYQATQKITYRISGVGIDQPPFGIFVVDKNTGDINITAIVDREET
PSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMILN
ATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGA
DKDGEGLSTQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDN
WLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVKNKAEFHQSVI
SRYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAA
SNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDEYTGKTSTGT
VYVRVPDFNDNCPTAVLEKDAVCSSSPSVVVSARTLNNRYTGPYTFALEDQPVKLPAVWS
ITTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTSYP
TTSPGTRYGRPHSGRLGPAAIGLLLLGLLLLLLAPLLLLTCDCGAGSTGGVTGGFIPVPD
GSEGTIHQWGIEGAHPEDKEITNICVPPVTANGADFMESSEVCTNTYARGTAVEGTSGME
MTTKLGAATESGGAAGFATGTVSGAASGFGAATGVGICSSGQSGTMRTRHSTGGTNKDYA
DGAISMNFLDSYFSQKAFACAEEDDGQEANDCLLIYDNEGADATGSPVGSVGCCSFIADD
LDDSFLDSLGPKFKKLAEISLGVDGEGKEVQPPSKDSGYGIESCGHPIEVQQTGFVKCQT
LSGSQGASALSTSGSVQPAVSIPDPLQHGNYLVTETYSASGSLVQPSTAGFDPLLTQNVI
VTERVICPISSVPGNLAGPTQLRGSHTMLCTEDPCSRLI
NT seq 3000 nt   +upstreamnt  +downstreamnt
atgatggggctcttccccagaactacaggggctctggccatcttcgtggtggtcatattg
gttcatggagaattgcgaatagagactaaaggtcaatatgatgaagaagagatgactatg
caacaagctaaaagaaggcaaaaacgtgaatgggtgaaatttgccaaaccctgcagagaa
ggagaagataactcaaaaagaaacccaattgccaagattacttcagattaccaagcaacc
cagaaaatcacctaccgaatctctggagtgggaatcgatcagccgccttttggaatcttt
gttgttgacaaaaacactggagatattaacataacagctatagtcgaccgggaggaaact
ccaagcttcctgatcacatgtcgggctctaaatgcccaaggactagatgtagagaaacca
cttatactaacggttaaaattttggatattaatgataatcctccagtattttcacaacaa
attttcatgggtgaaattgaagaaaatagtgcctcaaactcactggtgatgatactaaat
gccacagatgcagatgaaccaaaccacttgaattctaaaattgccttcaaaattgtctct
caggaaccagcaggcacacccatgttcctcctaagcagaaacactggggaagtccgtact
ttgaccaattctcttgaccgagagcaagctagcagctatcgtctggttgtgagtggtgca
gacaaagatggagaaggactatcaactcaatgtgaatgtaatattaaagtgaaagatgtc
aacgataacttcccaatgtttagagactctcagtattcagcacgtattgaagaaaatatt
ttaagttctgaattacttcgatttcaagtaacagatttggatgaagagtacacagataat
tggcttgcagtatatttctttacctctgggaatgaaggaaattggtttgaaatacaaact
gatcctagaactaatgaaggcatcctgaaagtggtgaaggctctagattatgaacaacta
caaagcgtgaaacttagtattgctgtcaaaaacaaagctgaatttcaccaatcagttatc
tctcgataccgagttcagtcaaccccagtcacaattcaggtaataaatgtaagagaagga
attgcattccgtcctgcttccaagacatttactgtgcaaaaaggcataagtagcaaaaaa
ttggtggattatatcctgggaacatatcaagccatcgatgaggacactaacaaagctgcc
tcaaatgtcaaatatgtcatgggacgtaacgatggtggatacctaatgattgattcaaaa
actgctgaaatcaaatttgtcaaaaatatgaaccgagattctactttcatagttaacaaa
acaatcacagctgaggttctggccatagatgaatacacgggtaaaacttctacaggcacg
gtatatgttagagtacccgatttcaatgacaattgtccaacagctgtcctcgaaaaagat
gcagtttgcagttcttcaccttccgtggttgtctccgctagaacactgaataatagatac
actggcccctatacatttgcactggaagatcaacctgtaaagttgcctgccgtatggagt
atcacaaccctcaatgctacctcggccctcctcagagcccaggaacagatacctcctgga
gtataccacatctccctggtacttacagacagtcagaacaatcggtgtgagatgccacgc
agcttgacactggaagtctgtcagtgtgacaacaggggcatctgtggaacttcttaccca
accacaagccctgggaccaggtatggcaggccgcactcagggaggctggggcctgccgcc
atcggcctgctgctccttggtctcctgctgctgctgttggccccccttctgctgttgacc
tgtgactgtggggcaggttctactgggggagtgacaggtggttttatcccagttcctgat
ggctcagaaggaacaattcatcagtggggaattgaaggagcccatcctgaagacaaggaa
atcacaaatatttgtgtgcctcctgtaacagccaatggagccgatttcatggaaagttct
gaagtttgtacaaatacgtatgccagaggcacagcggtggaaggcacttcaggaatggaa
atgaccactaagcttggagcagccactgaatctggaggtgctgcaggctttgcaacaggg
acagtgtcaggagctgcttcaggattcggagcagccactggagttggcatctgttcctca
gggcagtctggaaccatgagaacaaggcattccactggaggaaccaataaggactacgct
gatggggcgataagcatgaattttctggactcctacttttctcagaaagcatttgcctgt
gcggaggaagacgatggccaggaagcaaatgactgcttgttgatctatgataatgaaggc
gcagatgccactggttctcctgtgggctccgtgggttgttgcagttttattgctgatgac
ctggatgacagcttcttggactcacttggacccaaatttaaaaaacttgcagagataagc
cttggtgttgatggtgaaggcaaagaagttcagccaccctctaaagacagcggttatggg
attgaatcctgtggccatcccatagaagtccagcagacaggatttgttaagtgccagact
ttgtcaggaagtcaaggagcttctgctttgtccacctctgggtctgtccagccagctgtt
tccatccctgaccctctgcagcatggtaactatttagtaacggagacttactcggcttct
ggttccctcgtgcaaccttccactgcaggctttgatccacttctcacacaaaatgtgata
gtgacagaaagggtgatctgtcccatttccagtgttcctggcaacctagctggcccaacg
cagctacgagggtcacatactatgctctgtacagaggatccttgctcccgtctaatatga

  All links  
Disease (2)   
   OMIM (2)   
Gene (13)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (25)   
   RefSeq(nuc) (3)   
   GenBank (11)   
   EMBL (11)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (48)   

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