KEGG   Homo sapiens (human): 1840Help
Entry
1840              CDS       T01001                                 

Gene name
DTX1, RNF140, hDx-1
Definition
(RefSeq) deltex E3 ubiquitin ligase 1
  KO
K06058  deltex [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04330  Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    1840 (DTX1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    1840 (DTX1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     1840 (DTX1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    1840 (DTX1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DTC WWE zf-C3HC4 zf-rbx1 zf-RING_UBOX zf-RING_2 zf-RING_5 zf-ANAPC11 zf-UDP FANCL_C
Motif
Other DBs
NCBI-GeneID: 1840
NCBI-ProteinID: NP_004407
OMIM: 602582
HGNC: 3060
Ensembl: ENSG00000135144
Vega: OTTHUMG00000169610
Pharos: Q86Y01(Tbio)
UniProt: Q86Y01
Position
12q24.13
AA seq 620 aa AA seqDB search
MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSV
VLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTA
YDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLT
VGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG
PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQ
RTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP
PPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVT
ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG
TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN
NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY
LDNVLAELTAQGVSEAAAKA
NT seq 1863 nt NT seq  +upstreamnt  +downstreamnt
atgtcacggccaggccacggtgggctgatgcctgtgaatggtctgggcttcccaccgcag
aacgtggcccgggtggtggtgtgggagtggctgaatgagcacagccgctggcggccctac
acggccaccgtgtgccaccacattgagaacgtgctgaaggaggacgctcgcggttccgtg
gtcctggggcaggtggacgcccagcttgtgccctacatcatcgacctgcagtccatgcac
cagtttcgccaggacacaggcaccatgcggcccgtgcggcgcaacttctacgacccgtcg
tcggcgccgggcaagggcatcgtgtgggagtgggagaacgacggcggcgcatggacggcc
tacgatatggacatctgcatcaccatccagaacgcctacgagaagcagcacccgtggctc
gacctctcatcgctaggcttctgctacctcatctacttcaacagcatgtcgcagatgaac
cgccagacgcgccggcgccgccgcctgcgccgccgcctggacctcgcctacccgctcacc
gtgggctccatccctaagtcgcagtcgtggcccgtgggcgccagctcgggccagccctgc
tcctgccagcagtgcctgctggtcaacagcacgcgcgccgcctccaacgccatcctggcc
tcgcagcgccgcaaggcgccccccgcgcccccgctgccgccgccgccgccacctggaggg
cctccaggcgcgcttgccgtgcgccccagcgccaccttcacaggcgccgcgctctgggca
gcgcccgccgccggccccgccgagcccgcgccgcctcccggggcgcccccacggagcccg
ggcgcccccggcggagcgcgcaccccggggcagaacaacctcaaccggcccgggccccag
cgcaccaccagcgtgagcgcgcgcgcctccatcccgccgggggtccccgcactcccggtg
aagaacttgaatggtactgggccggtccatccggccctggcagggatgaccgggatactg
ctgtgcgcggccgggctgcccgtgtgcctgacgcgggcccccaagcccatcctgcacccg
ccgcccgtgagcaagagcgacgtgaagcccgtgcctggcgtgcccggggtgtgccgcaag
accaagaagaagcaccttaaaaagagtaagaatcccgaggatgtggttcgaagatacatg
cagaaggtgaaaaacccacctgatgaggactgcaccatctgcatggagcgactggtcaca
gcatcaggctacgagggcgtgcttcggcacaagggcgtgcggcctgagctcgtgggccgc
ctgggccgctgtggccacatgtaccacctgctgtgcctcgtggccatgtactccaatggc
aacaaggatggcagcctgcagtgccccacctgcaaggccatctacggggagaagacgggt
acgcagccgcctgggaagatggagttccacctcatcccccactcgctgcccggcttccct
gatacccagaccatccgcatcgtctatgacatccccacaggcatccagggccctgagcac
cccaaccccgggaagaagttcaccgcaagaggattccctcgccactgctatctacccaac
aacgagaaaggccggaaggtgctgcggctgctcatcacggcctgggagagaagactcatc
ttcactatcggcacgtccaacaccacgggcgagtcggacaccgtggtgtggaacgagatc
caccacaagaccgagtttggatccaacctcacgggccacggctacccggacgctagctac
ctagacaacgtgctggctgagctcacagcccagggcgtatccgaggctgcagccaaggct
tga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (41)   
   KEGG ORTHOLOGY (1)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (10)   
   Pfam (10)   
All databases (72)   

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