KEGG   Homo sapiens (human): 1844Help
Entry
1844              CDS       T01001                                 

Gene name
DUSP2, PAC-1, PAC1
Definition
(RefSeq) dual specificity phosphatase 2
  KO
K04459  dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    1844 (DUSP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    1844 (DUSP2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1844 (DUSP2)
    3.1.3.48  protein-tyrosine-phosphatase
     1844 (DUSP2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1844 (DUSP2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DSPc Rhodanese Y_phosphatase Myotub-related
Motif
Other DBs
NCBI-GeneID: 1844
NCBI-ProteinID: NP_004409
OMIM: 603068
HGNC: 3068
Ensembl: ENSG00000158050
Vega: OTTHUMG00000130456
Pharos: Q05923(Tbio)
UniProt: Q05923
Structure
PDB: 

Position
2q11.2
AA seq 314 aa AA seqDB search
MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR
GPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRA
GPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYL
FLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAI
GFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSF
MGQLLQFETQVLCH
NT seq 945 nt NT seq  +upstreamnt  +downstreamnt
atggggctggaggcggcgcgcgagctggagtgcgcggcgctgggcacgctgctgcgggat
ccgcgggaggcggaacgcacgctgctgctggactgccgccccttcctggccttctgccgg
cgccacgtgcgcgccgcgcggccagtgccttggaacgcgctgctgcggcgccgcgcgcgc
ggccctcctgccgccgttctcgcctgcctgctgcccgaccgcgcgctgcggacgcgcctg
gtccgcggggagctggcgcgggccgtggtgctggacgagggcagtgcctcggtggcggag
ctccggcccgacagcccggctcatgtgctgctggccgcgctgctgcacgagacccgcgcg
gggcccactgccgtgtacttcctgcgaggaggcttcgacggcttccagggctgctgtccc
gatctgtgctctgaggcccccgcccctgcgctgccgccaacaggggacaaaaccagccgc
tccgactccagggctcctgtctacgaccagggtggccctgtggagatcttgccctacctg
ttcctgggcagctgcagtcactcgtcagacctgcaggggctgcaggcctgtggcatcaca
gccgtcctcaacgtgtccgccagctgccccaaccactttgagggccttttccgctacaag
agtatccctgtggaggacaaccagatggtggagatcagtgcctggttccaggaggccata
ggcttcattgactgggtgaagaacagcggaggccgggtgctggtgcactgccaggcgggt
atctcgcgctctgccaccatctgtctggcatacctcatgcagagtcgccgtgtgcggctg
gacgaggcctttgacttcgttaagcagcgccggggggtcatctcccccaacttcagtttc
atggggcagctgctgcagtttgagacccaggtgctgtgtcactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (4)   
   Pfam (4)   
All databases (38)   

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