KEGG   Homo sapiens (human): 1844
Entry
1844              CDS       T01001                                 
Symbol
DUSP2, PAC-1, PAC1
Name
(RefSeq) dual specificity phosphatase 2
  KO
K04459  dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04148  Efferocytosis
Network
nt06526  MAPK signaling
  Element
N01593  Regulation of GF-RTK-RAS-ERK signaling, PTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    1844 (DUSP2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    1844 (DUSP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    1844 (DUSP2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1844 (DUSP2)
    3.1.3.48  protein-tyrosine-phosphatase
     1844 (DUSP2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1844 (DUSP2)
SSDB
Motif
Pfam: DSPc Rhodanese PTP-SAK Tc-R-P Y_phosphatase PTP-NADK Init_tRNA_PT
Other DBs
NCBI-GeneID: 1844
NCBI-ProteinID: NP_004409
OMIM: 603068
HGNC: 3068
Ensembl: ENSG00000158050
UniProt: Q05923
Structure
Position
2:complement(96143169..96145440)
AA seq 314 aa
MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR
GPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRA
GPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYL
FLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAI
GFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSF
MGQLLQFETQVLCH
NT seq 945 nt   +upstreamnt  +downstreamnt
atggggctggaggcggcgcgcgagctggagtgcgcggcgctgggcacgctgctgcgggat
ccgcgggaggcggaacgcacgctgctgctggactgccgccccttcctggccttctgccgg
cgccacgtgcgcgccgcgcggccagtgccttggaacgcgctgctgcggcgccgcgcgcgc
ggccctcctgccgccgttctcgcctgcctgctgcccgaccgcgcgctgcggacgcgcctg
gtccgcggggagctggcgcgggccgtggtgctggacgagggcagtgcctcggtggcggag
ctccggcccgacagcccggctcatgtgctgctggccgcgctgctgcacgagacccgcgcg
gggcccactgccgtgtacttcctgcgaggaggcttcgacggcttccagggctgctgtccc
gatctgtgctctgaggcccccgcccctgcgctgccgccaacaggggacaaaaccagccgc
tccgactccagggctcctgtctacgaccagggtggccctgtggagatcttgccctacctg
ttcctgggcagctgcagtcactcgtcagacctgcaggggctgcaggcctgtggcatcaca
gccgtcctcaacgtgtccgccagctgccccaaccactttgagggccttttccgctacaag
agtatccctgtggaggacaaccagatggtggagatcagtgcctggttccaggaggccata
ggcttcattgactgggtgaagaacagcggaggccgggtgctggtgcactgccaggcgggt
atctcgcgctctgccaccatctgtctggcatacctcatgcagagtcgccgtgtgcggctg
gacgaggcctttgacttcgttaagcagcgccggggggtcatctcccccaacttcagtttc
atggggcagctgctgcagtttgagacccaggtgctgtgtcactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (9)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (12)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (36)   

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