KEGG   Homo sapiens (human): 1844Help
Entry
1844              CDS       T01001                                 

Gene name
DUSP2, PAC-1, PAC1
Definition
(RefSeq) dual specificity phosphatase 2
  KO
K04459  dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    1844 (DUSP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    1844 (DUSP2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1844 (DUSP2)
    3.1.3.48  protein-tyrosine-phosphatase
     1844 (DUSP2)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1844 (DUSP2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DSPc Rhodanese Y_phosphatase Myotub-related
Motif
Other DBs
NCBI-GeneID: 1844
NCBI-ProteinID: NP_004409
OMIM: 603068
HGNC: 3068
Ensembl: ENSG00000158050
Vega: OTTHUMG00000130456
Pharos: Q05923(Tbio)
UniProt: Q05923
Structure
PDB: 

Position
2q11.2
AA seq 314 aa AA seqDB search
MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR
GPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRA
GPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYL
FLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAI
GFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSF
MGQLLQFETQVLCH
NT seq 945 nt NT seq  +upstreamnt  +downstreamnt
atggggctggaggcggcgcgcgagctggagtgcgcggcgctgggcacgctgctgcgggat
ccgcgggaggcggaacgcacgctgctgctggactgccgccccttcctggccttctgccgg
cgccacgtgcgcgccgcgcggccagtgccttggaacgcgctgctgcggcgccgcgcgcgc
ggccctcctgccgccgttctcgcctgcctgctgcccgaccgcgcgctgcggacgcgcctg
gtccgcggggagctggcgcgggccgtggtgctggacgagggcagtgcctcggtggcggag
ctccggcccgacagcccggctcatgtgctgctggccgcgctgctgcacgagacccgcgcg
gggcccactgccgtgtacttcctgcgaggaggcttcgacggcttccagggctgctgtccc
gatctgtgctctgaggcccccgcccctgcgctgccgccaacaggggacaaaaccagccgc
tccgactccagggctcctgtctacgaccagggtggccctgtggagatcttgccctacctg
ttcctgggcagctgcagtcactcgtcagacctgcaggggctgcaggcctgtggcatcaca
gccgtcctcaacgtgtccgccagctgccccaaccactttgagggccttttccgctacaag
agtatccctgtggaggacaaccagatggtggagatcagtgcctggttccaggaggccata
ggcttcattgactgggtgaagaacagcggaggccgggtgctggtgcactgccaggcgggt
atctcgcgctctgccaccatctgtctggcatacctcatgcagagtcgccgtgtgcggctg
gacgaggcctttgacttcgttaagcagcgccggggggtcatctcccccaacttcagtttc
atggggcagctgctgcagtttgagacccaggtgctgtgtcactga

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