KEGG   Homo sapiens (human): 1845
Entry
1845              CDS       T01001                                 
Symbol
DUSP3, VHR
Name
(RefSeq) dual specificity phosphatase 3
  KO
K17614  dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Network
nt06526  MAPK signaling
  Element
N01593  Regulation of GF-RTK-RAS-ERK signaling, PTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    1845 (DUSP3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    1845 (DUSP3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1845 (DUSP3)
    3.1.3.48  protein-tyrosine-phosphatase
     1845 (DUSP3)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Atypical DSPs
    1845 (DUSP3)
SSDB
Motif
Pfam: DSPc Tc-R-P PTP-SAK Init_tRNA_PT Y_phosphatase PTP-NADK Y_phosphatase2 PHA01746 Myotub-related
Other DBs
NCBI-GeneID: 1845
NCBI-ProteinID: NP_004081
OMIM: 600183
HGNC: 3069
Ensembl: ENSG00000108861
UniProt: P51452
Structure
Position
17:complement(43766125..43778977)
AA seq 185 aa
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
NT seq 558 nt   +upstreamnt  +downstreamnt
atgtcgggctcgttcgagctctcggtgcaggatctcaacgacctgctctcggacggcagc
ggctgctacagcctcccgagccagccctgcaacgaggtcaccccgcggatctacgtgggc
aacgcgtctgtggctcaggacatccccaagctgcagaaactaggcatcacccatgtgctg
aacgcggctgagggcaggtccttcatgcacgtcaacaccaatgccaacttctacaaggac
tccggcatcacatacctgggcatcaaggccaacgacacacaggagttcaacctcagcgct
tactttgaaagggctgccgacttcattgaccaggctttggctcaaaagaatggccgggtg
ctcgtccactgccgggaaggttatagccgctccccaacgctagttatcgcctacctcatg
atgcggcagaagatggacgtcaagtctgccctgagcatcgtgaggcagaaccgtgagatc
ggccccaacgatggcttcctggcccagctctgccagctcaatgacagactagccaaggag
gggaagttgaaaccctag

  All links  
Disease (1)   
   OMIM (1)   
Gene (15)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (35)   
   RefSeq(nuc) (1)   
   GenBank (17)   
   EMBL (17)   
3D Structure (9)   
   PDB (9)   
Protein domain (9)   
   Pfam (9)   
All databases (72)   

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