KEGG   Homo sapiens (human): 1852
Entry
1852              CDS       T01001                                 
Symbol
DUSP9, MKP-4, MKP4
Name
(RefSeq) dual specificity phosphatase 9
  KO
K18498  dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
Network
nt06526  MAPK signaling
  Element
N01593  Regulation of GF-RTK-RAS-ERK signaling, PTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    1852 (DUSP9)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    1852 (DUSP9)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    1852 (DUSP9)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     1852 (DUSP9)
    3.1.3.48  protein-tyrosine-phosphatase
     1852 (DUSP9)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    1852 (DUSP9)
SSDB
Motif
Pfam: DSPc Tc-R-P Rhodanese PTP-SAK Init_tRNA_PT Y_phosphatase PTPlike_phytase CDKN3 Y_phosphatase2
Other DBs
NCBI-GeneID: 1852
NCBI-ProteinID: NP_001305432
OMIM: 300134
HGNC: 3076
Ensembl: ENSG00000130829
UniProt: Q99956 Q6P9C2
Structure
Position
X:153642441..153651326
AA seq 384 aa
MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLS
VRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA
YYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADR
DSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNL
PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTV
TVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA
SAASNPPSFFTTPTSDGAFELAPT
NT seq 1155 nt   +upstreamnt  +downstreamnt
atggagggtctgggccgctcgtgcctgtggctgcgtcgggagctgtcgcccccgcggccg
cggctcctgctcctggactgccgcagccgcgagctgtacgagtcggcgcgcatcggtggg
gcgctgagcgtggccctgccggcgctcctgctgcgccgcctgcggaggggcagcctgtcg
gtgcgcgcgctcctgcctgggccgccgctgcagccgcccccgcctgcccccgtgctcctg
tacgaccagggcgggggccggcgccggcgcggggaggccgaggccgaggccgaggagtgg
gaggccgagtcggtgctgggcaccctgctgcagaagctgcgagaggaaggctacctggcc
tactacctccagggaggcttcagcagattccaggccgagtgccctcacctgtgtgagacc
agccttgctggccgtgccggctccagcatggcgccggtgcccggtccagtgcccgtggtg
gggttgggcagcctgtgcctgggctccgactgctctgatgcggaatccgaggctgaccgc
gactccatgagctgtggcctggattcggagggtgccacacccccaccagtggggctgcgg
gcatccttccctgtccagatcctgcccaacctctatctgggcagtgcccgggattccgcc
aatttggagagcctggccaaactgggcatccgctacatcctcaatgtcacccccaacctc
ccaaacttcttcgagaagaatggtgactttcactacaagcagatccccatctccgaccac
tggagccagaacctgtcgcggttctttccggaggccattgagttcattgatgaggccttg
tcccagaactgcggggtgctcgtccactgcttggcgggggtcagccgttctgtcaccgtc
actgtggcctacctcatgcagaagctccacctctctctcaacgatgcctatgacctggtc
aagaggaagaagtctaacatctcccccaacttcaacttcatggggcagttgctggacttt
gagcgcagcttgcggctggaggagcgccactcgcaggagcagggcagtggggggcaggca
tctgcggcctccaacccgccctccttcttcaccacccccaccagtgatggcgccttcgag
ctggcccccacctag

  All links  
Disease (1)   
   OMIM (1)   
Gene (17)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (22)   
   RefSeq(nuc) (6)   
   GenBank (8)   
   EMBL (8)   
3D Structure (2)   
   PDB (2)   
Protein domain (9)   
   Pfam (9)   
All databases (60)   

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