KEGG   Homo sapiens (human): 1857Help
Entry
1857              CDS       T01001                                 

Gene name
DVL3, DRS3
Definition
(RefSeq) dishevelled segment polarity protein 3
  KO
K02353  segment polarity protein dishevelled
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
hsa04310  Wnt signaling pathway
hsa04330  Notch signaling pathway
hsa04390  Hippo signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04916  Melanogenesis
hsa04934  Cushing syndrome
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05217  Basal cell carcinoma
hsa05224  Breast cancer
hsa05225  Hepatocellular carcinoma
hsa05226  Gastric cancer
Module
hsa_M00677  Wnt signaling
Network
N00056  Wnt signaling pathway
N00059  FZD7-overexpression to Wnt signaling pathway
N00060  LRP6-overexpression to Wnt signaling pathway
Disease
H00485  Robinow syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    1857 (DVL3)
   04330 Notch signaling pathway
    1857 (DVL3)
   04390 Hippo signaling pathway
    1857 (DVL3)
   04150 mTOR signaling pathway
    1857 (DVL3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    1857 (DVL3)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    1857 (DVL3)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    1857 (DVL3)
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    1857 (DVL3)
   05226 Gastric cancer
    1857 (DVL3)
   05217 Basal cell carcinoma
    1857 (DVL3)
   05224 Breast cancer
    1857 (DVL3)
  09167 Endocrine and metabolic diseases
   04934 Cushing syndrome
    1857 (DVL3)
  09172 Infectious diseases: Viral
   05165 Human papillomavirus infection
    1857 (DVL3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Dsh_C Dishevelled DIX PDZ DEP PDZ_6 Shufflon_N
Motif
Other DBs
NCBI-GeneID: 1857
NCBI-ProteinID: NP_004414
OMIM: 601368
HGNC: 3087
Ensembl: ENSG00000161202
Vega: OTTHUMG00000156841
Pharos: Q92997(Tbio)
UniProt: Q92997
Position
3q27.1
AA seq 716 aa AA seqDB search
MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEI
SDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPH
AGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLM
SSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITD
STMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLL
QVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAA
WVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMA
SPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHT
VNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQY
PPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGG
SGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPP
LYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM
NT seq 2151 nt NT seq  +upstreamnt  +downstreamnt
atgggcgagaccaagatcatctaccacttggatgggcaggagacgccgtaccttgtgaag
ctgcccctgcccgccgagcgcgtcaccttggcggactttaagggcgttttgcagcgaccc
agctataagttcttcttcaagtctatggacgacgatttcggagtggtgaaggaggagatc
tcggatgacaatgccaagctaccatgcttcaatggccgggtggtgtcctggctggtgtca
gctgagggctcacacccagacccagcccccttctgtgctgataacccatcggagctgcca
ccacctatggagcgcacgggaggcatcggggactcccgacccccatccttccaccctcat
gctggtgggggcagccaggagaacctggacaatgacacagagacggactctttggtgtct
gcccagcgagagcggccacgccggagggatggcccagagcatgcaacccggctaaatgga
actgcgaagggggaacggcggcgagaaccagggggttatgatagctcatccacccttatg
agcagtgagctggagaccaccagcttctttgactcagatgaggatgactccaccagcagg
ttcagcagctccacagaacagagcagtgcctcacgcctgatgagaagacacaagcggcgg
cggcggaagcagaaggtttctcggattgagcggtcctcgtccttcagcagcatcacggac
tccaccatgtcactcaacatcatcacggtcactctcaacatggaaaaatataacttcttg
ggcatctccattgtgggccaaagcaacgagcgtggtgacggcggcatctacattggctct
atcatgaagggtggggccgtggctgctgatggacgcatcgagccaggagatatgttgtta
caggtaaacgagatcaactttgagaacatgagtaatgacgatgcagtccgggtactgcgg
gagattgtgcacaaaccggggcccatcaccctgactgtagccaagtgctgggacccaagt
ccacgtggttgcttcacattgcccaggagcgagcccatccggcccattgaccctgcggcc
tgggtctcccacactgcagccatgaccggcaccttccctgcatacggcatgagcccctcc
ctgagcaccatcacctccaccagctcctccatcaccagttccatccctgacacagagcgc
ctagacgacttccacttgtccatccacagtgacatggctgccatcgtaaaagccatggcc
tcccctgaatcagggttggaggtccgtgaccgcatgtggctcaagattaccatccctaat
gctttcatcggctcagatgtggtggactggctgtaccacaatgtggaaggcttcacggac
cggagggaggcccgcaagtatgccagcaacctgctgaaagctggcttcatccgccatacc
gtcaacaagatcaccttctccgagcagtgctactacatcttcggtgacctctgcggcaac
atggccaacctgtctctccacgatcacgatggctccagtggcgcctctgaccaggacaca
ctggcccctttgccgcacccgggggccgccccttggcccatggctttcccgtaccagtac
ccgccacccccgcacccatacaacccgcacccgggcttcccggagctgggctacagctac
ggcgggggcagcgccagcagtcagcacagcgaaggcagtcggagcagtggctccaaccgt
agcggcagcgatcggaggaaggagaaggacccgaaggccggggactccaagtccgggggc
agcggcagcgaatcggaccacaccacacgcagcagcctgcgggggccgcgggagcgggcg
cccagcgagcgctcagggccggcggccagcgagcacagccaccgcagccaccattccctg
gccagcagccttcgcagccaccacacacacccgagctacggtcctcccggagtgccccct
ctctacggcccccccatgctgatgatgcccccgccgcccgcggccatggggcccccagga
gcccctccgggccgcgacctggcctcagtgcccccggaactgaccgccagcagacagtcc
ttccgcatggccatgggaaaccccagtgagttctttgtggatgtgatgtga

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