KEGG   Homo sapiens (human): 187
Entry
187               CDS       T01001                                 

Gene name
APLNR, AGTRL1, APJ, APJR, HG11
Definition
(RefSeq) apelin receptor
  KO
K04174  apelin receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04371  Apelin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    187 (APLNR)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    187 (APLNR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    187 (APLNR)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Apelin
    187 (APLNR)
Motif
Pfam: 7tm_1 7TM_GPCR_Srv 7tm_4 TAS2R
Other DBs
NCBI-GeneID: 187
NCBI-ProteinID: NP_005152
OMIM: 600052
HGNC: 339
Ensembl: ENSG00000134817
Vega: OTTHUMG00000167021
Pharos: P35414(Tchem)
UniProt: P35414 B3KQN4 B2RDH3
Structure
PDB: 
2LOT 2LOU 2LOV 2LOW

Position
11q12.1
AA seq 380 aa
MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK
RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL
TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ
CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL
RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV
NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK
GGEQMHEKSIPYSQETLVVD
NT seq 1143 nt   +upstreamnt  +downstreamnt
atggaggaaggtggtgattttgacaactactatggggcagacaaccagtctgagtgtgag
tacacagactggaaatcctcgggggccctcatccctgccatctacatgttggtcttcctc
ctgggcaccacgggcaacggtctggtgctctggaccgtgtttcggagcagccgggagaag
aggcgctcagctgatatcttcattgctagcctggcggtggctgacctgaccttcgtggtg
acgctgcccctgtgggctacctacacgtaccgggactatgactggccctttgggaccttc
ttctgcaagctcagcagctacctcatcttcgtcaacatgtacgccagcgtcttctgcctc
accggcctcagcttcgaccgctacctggccatcgtgaggccagtggccaatgctcggctg
aggctgcgggtcagcggggccgtggccacggcagttctttgggtgctggccgccctcctg
gccatgcctgtcatggtgttacgcaccaccggggacttggagaacaccactaaggtgcag
tgctacatggactactccatggtggccactgtgagctcagagtgggcctgggaggtgggc
cttggggtctcgtccaccaccgtgggctttgtggtgcccttcaccatcatgctgacctgt
tacttcttcatcgcccaaaccatcgctggccacttccgcaaggaacgcatcgagggcctg
cggaagcggcgccggctgctcagcatcatcgtggtgctggtggtgacctttgccctgtgc
tggatgccctaccacctggtgaagacgctgtacatgctgggcagcctgctgcactggccc
tgtgactttgacctcttcctcatgaacatcttcccctactgcacctgcatcagctacgtc
aacagctgcctcaaccccttcctctatgcctttttcgacccccgcttccgccaggcctgc
acctccatgctctgctgtggccagagcaggtgcgcaggcacctcccacagcagcagtggg
gagaagtcagccagctactcttcggggcacagccaggggcccggccccaacatgggcaag
ggtggagaacagatgcacgagaaatccatcccctacagccaggagacccttgtggttgac
tag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
Protein domain (4)   
   Pfam (4)   
All databases (52)   

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