KEGG   Homo sapiens (human): 1874
Entry
1874              CDS       T01001                                 
Symbol
E2F4, E2F-4
Name
(RefSeq) E2F transcription factor 4
  KO
K04682  transcription factor E2F4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04218  Cellular senescence
hsa04350  TGF-beta signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    1874 (E2F4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    1874 (E2F4)
   04218 Cellular senescence
    1874 (E2F4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    1874 (E2F4)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix cell cycle-controlling factors, E2F
    1874 (E2F4)
SSDB
Motif
Pfam: E2F_CC-MB E2F_TDP HTH_Cmi2_C DivIC CCDC92
Other DBs
NCBI-GeneID: 1874
NCBI-ProteinID: NP_001941
OMIM: 600659
HGNC: 3118
Ensembl: ENSG00000205250
UniProt: Q16254
Structure
Position
16:67192155..67198918
AA seq 413 aa
MAEAGPQAPPPPGTPSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYD
ITNVLEGIGLIEKKSKNSIQWKGVGPGCNTREIADKLIELKAEIEELQQREQELDQHKVW
VQQSIRNVTEDVQNSCLAYVTHEDICRCFAGDTLLAIRAPSGTSLEVPIPEGLNGQKKYQ
IHLKSVSGPIEVLLVNKEAWSSPPVAVPVPPPEDLLQSPSAVSTPPPLPKPALAQSQEAS
RPNSPQLTPTAVPGSAEVQGMAGPAAEITVSGGPGTDSKDSGELSSLPLGPTTLDTRPLQ
SSALLDSSSSSSSSSSSSSNSNSSSSSGPNPSTSFEPIKADPTGVLELPKELSEIFDPTR
ECMSSELLEELMSSEVFAPLLRLSPPPGDHDYIYNLDESEGVCDLFDVPVLNL
NT seq 1242 nt   +upstreamnt  +downstreamnt
atggcggaggccgggccacaggcgccgccgcccccgggcactccaagccggcacgaaaag
agcctgggactgctcaccaccaagttcgtgtcccttctgcaggaggccaaggacggcgtg
cttgacctcaagctggcagctgacaccctagctgtacgccagaagcggcggatttacgac
attaccaatgttttggaaggtatcgggctaatcgagaaaaagtccaagaacagcatccag
tggaagggtgtggggcctggctgcaatacccgggagattgctgacaaactgattgagctc
aaggcagagatcgaggagctgcagcagcgggagcaagaactagaccagcacaaggtgtgg
gtgcagcagagcatccggaacgtcacagaggacgtgcagaacagctgtttggcctacgtc
actcatgaggacatctgcagatgctttgctggagataccctcttggccatccgggcccca
tcaggcaccagcctggaggtgcccatcccagagggtctcaatgggcagaagaagtaccag
attcacctgaagagtgtgagtggtcccattgaggttctgctggtgaacaaggaggcatgg
agctcaccccctgtggctgtgcctgtgccaccacctgaagatttgctccagagcccatct
gctgtttctacacctccacctctgcccaagcctgccctagcccagtcccaggaagcctca
cgtccaaatagtcctcagctcactcccactgctgtccctggcagtgcagaagtccaggga
atggctggcccagcagctgagatcacagtgagtggcggccctgggactgatagcaaggac
agtggtgagctcagttcactcccactgggcccaacaacactggacacccggccactgcag
tcttctgccctgctggacagcagcagcagcagcagcagcagcagcagcagcagcagcaac
agtaacagcagcagttcgtccggacccaacccttctacctcctttgagcccatcaaggca
gaccccacaggtgttttggaactccccaaagagctgtcagaaatctttgatcccacacga
gagtgcatgagctcggagctgctggaggagttgatgtcctcagaagtgtttgcccctctg
cttcgtctttctccacccccgggagaccacgattatatctacaacctggacgagagtgaa
ggtgtctgtgacctctttgatgtgcctgttctcaacctctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (27)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (57)   

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KEGG   Homo sapiens (human): 1875
Entry
1875              CDS       T01001                                 
Symbol
E2F5, E2F-5
Name
(RefSeq) E2F transcription factor 5
  KO
K04682  transcription factor E2F4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04218  Cellular senescence
hsa04350  TGF-beta signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    1875 (E2F5)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    1875 (E2F5)
   04218 Cellular senescence
    1875 (E2F5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    1875 (E2F5)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix cell cycle-controlling factors, E2F
    1875 (E2F5)
SSDB
Motif
Pfam: E2F_CC-MB E2F_TDP FAD_binding_5 SKA2
Other DBs
NCBI-GeneID: 1875
NCBI-ProteinID: NP_001942
OMIM: 600967
HGNC: 3119
Ensembl: ENSG00000133740
UniProt: Q15329
Structure
Position
8:85177154..85214518
AA seq 346 aa
MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT
KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG
CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN
CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV
FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISG
DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
NT seq 1041 nt   +upstreamnt  +downstreamnt
atggcggcggcagagcccgcgagctcgggccagcaggcgccggcagggcaggggcagggc
cagcggccgccgccgcagcctccgcaggcgcaagccccgcagccgcccccgccgccgcag
ctcgggggcgccgggggcggcagcagcaggcacgagaagagcctggggctgctcactacc
aagttcgtgtcgctgctgcaggaggccaaggacggcgttctggatctcaaagcggctgct
gatactttggctgtgaggcaaaaaaggagaatttatgatatcaccaatgtcttagaggga
attgacttgattgaaaaaaagtcaaaaaacagtatccagtggaaaggtgtaggtgctggc
tgtaatactaaagaagtcatagatagattaagatatcttaaagctgaaattgaagatcta
gaactgaaggaaagagaacttgatcagcagaagttgtggctacagcaaagcatcaaaaat
gtgatggacgattccattaataatagattttcctatgtaactcatgaagacatctgtaat
tgctttaatggtgatacacttttggccattcaggcaccttctggtacacaactggaggta
cccattccagaaatgggtcagaatggacaaaagaaataccagatcaatctaaagagtcat
tcaggacctatccatgtgctgcttataaataaagagtcgagttcatctaagcccgtggtt
tttcctgttcccccacctgatgacctcacacagccttcctcccagtccttgactccagtg
actccacagaaatccagcatggcaactcaaaatctgcctgagcaacatgtctctgaaaga
agccaggctctgcagcagacatcagctacagatatatcttcagcaggatctattagtgga
gatatcattgatgagttaatgtcttctgacgtgtttcctctcttaaggctttctcctacc
ccggcagatgactacaactttaatttagatgataacgaaggagtttgtgatctgtttgat
gtccagatactaaattattag

  All links  
Disease (1)   
   OMIM (1)   
Gene (8)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (42)   

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