KEGG   Homo sapiens (human): 1874
Entry
1874              CDS       T01001                                 

Gene name
E2F4, E2F-4
Definition
(RefSeq) E2F transcription factor 4
  KO
K04682  transcription factor E2F4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04218  Cellular senescence
hsa04350  TGF-beta signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    1874 (E2F4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    1874 (E2F4)
   04218 Cellular senescence
    1874 (E2F4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    1874 (E2F4)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix cell cycle-controlling factors, E2F
    1874 (E2F4)
Motif
Pfam: E2F_CC-MB E2F_TDP DivIC DUF3584
Other DBs
NCBI-GeneID: 1874
NCBI-ProteinID: NP_001941
OMIM: 600659
HGNC: 3118
Ensembl: ENSG00000205250
Vega: OTTHUMG00000172975
Pharos: Q16254(Tbio)
UniProt: Q16254
Structure
PDB: 
5TUU 1CF7

Position
16q22.1
AA seq 413 aa
MAEAGPQAPPPPGTPSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYD
ITNVLEGIGLIEKKSKNSIQWKGVGPGCNTREIADKLIELKAEIEELQQREQELDQHKVW
VQQSIRNVTEDVQNSCLAYVTHEDICRCFAGDTLLAIRAPSGTSLEVPIPEGLNGQKKYQ
IHLKSVSGPIEVLLVNKEAWSSPPVAVPVPPPEDLLQSPSAVSTPPPLPKPALAQSQEAS
RPNSPQLTPTAVPGSAEVQGMAGPAAEITVSGGPGTDSKDSGELSSLPLGPTTLDTRPLQ
SSALLDSSSSSSSSSSSSSNSNSSSSSGPNPSTSFEPIKADPTGVLELPKELSEIFDPTR
ECMSSELLEELMSSEVFAPLLRLSPPPGDHDYIYNLDESEGVCDLFDVPVLNL
NT seq 1242 nt   +upstreamnt  +downstreamnt
atggcggaggccgggccacaggcgccgccgcccccgggcactccaagccggcacgaaaag
agcctgggactgctcaccaccaagttcgtgtcccttctgcaggaggccaaggacggcgtg
cttgacctcaagctggcagctgacaccctagctgtacgccagaagcggcggatttacgac
attaccaatgttttggaaggtatcgggctaatcgagaaaaagtccaagaacagcatccag
tggaagggtgtggggcctggctgcaatacccgggagattgctgacaaactgattgagctc
aaggcagagatcgaggagctgcagcagcgggagcaagaactagaccagcacaaggtgtgg
gtgcagcagagcatccggaacgtcacagaggacgtgcagaacagctgtttggcctacgtc
actcatgaggacatctgcagatgctttgctggagataccctcttggccatccgggcccca
tcaggcaccagcctggaggtgcccatcccagagggtctcaatgggcagaagaagtaccag
attcacctgaagagtgtgagtggtcccattgaggttctgctggtgaacaaggaggcatgg
agctcaccccctgtggctgtgcctgtgccaccacctgaagatttgctccagagcccatct
gctgtttctacacctccacctctgcccaagcctgccctagcccagtcccaggaagcctca
cgtccaaatagtcctcagctcactcccactgctgtccctggcagtgcagaagtccaggga
atggctggcccagcagctgagatcacagtgagtggcggccctgggactgatagcaaggac
agtggtgagctcagttcactcccactgggcccaacaacactggacacccggccactgcag
tcttctgccctgctggacagcagcagcagcagcagcagcagcagcagcagcagcagcaac
agtaacagcagcagttcgtccggacccaacccttctacctcctttgagcccatcaaggca
gaccccacaggtgttttggaactccccaaagagctgtcagaaatctttgatcccacacga
gagtgcatgagctcggagctgctggaggagttgatgtcctcagaagtgtttgcccctctg
cttcgtctttctccacccccgggagaccacgattatatctacaacctggacgagagtgaa
ggtgtctgtgacctctttgatgtgcctgttctcaacctctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (20)   
   RefSeq(nuc) (2)   
   GenBank (9)   
   EMBL (9)   
Protein domain (4)   
   Pfam (4)   
All databases (64)   

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KEGG   Homo sapiens (human): 1875
Entry
1875              CDS       T01001                                 

Gene name
E2F5, E2F-5
Definition
(RefSeq) E2F transcription factor 5
  KO
K04682  transcription factor E2F4/5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04218  Cellular senescence
hsa04350  TGF-beta signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    1875 (E2F5)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    1875 (E2F5)
   04218 Cellular senescence
    1875 (E2F5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    1875 (E2F5)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix cell cycle-controlling factors, E2F
    1875 (E2F5)
Motif
Pfam: E2F_CC-MB E2F_TDP FAD_binding_5 TMEM171
Other DBs
NCBI-GeneID: 1875
NCBI-ProteinID: NP_001942
OMIM: 600967
HGNC: 3119
Ensembl: ENSG00000133740
Vega: OTTHUMG00000164785
Pharos: Q15329(Tbio)
UniProt: Q15329
Structure
PDB: 
5TUV

Position
8q21.2
AA seq 346 aa
MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTT
KFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAG
CNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICN
CFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVV
FPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISG
DIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
NT seq 1041 nt   +upstreamnt  +downstreamnt
atggcggcggcagagcccgcgagctcgggccagcaggcgccggcagggcaggggcagggc
cagcggccgccgccgcagcctccgcaggcgcaagccccgcagccgcccccgccgccgcag
ctcgggggcgccgggggcggcagcagcaggcacgagaagagcctggggctgctcactacc
aagttcgtgtcgctgctgcaggaggccaaggacggcgttctggatctcaaagcggctgct
gatactttggctgtgaggcaaaaaaggagaatttatgatatcaccaatgtcttagaggga
attgacttgattgaaaaaaagtcaaaaaacagtatccagtggaaaggtgtaggtgctggc
tgtaatactaaagaagtcatagatagattaagatatcttaaagctgaaattgaagatcta
gaactgaaggaaagagaacttgatcagcagaagttgtggctacagcaaagcatcaaaaat
gtgatggacgattccattaataatagattttcctatgtaactcatgaagacatctgtaat
tgctttaatggtgatacacttttggccattcaggcaccttctggtacacaactggaggta
cccattccagaaatgggtcagaatggacaaaagaaataccagatcaatctaaagagtcat
tcaggacctatccatgtgctgcttataaataaagagtcgagttcatctaagcccgtggtt
tttcctgttcccccacctgatgacctcacacagccttcctcccagtccttgactccagtg
actccacagaaatccagcatggcaactcaaaatctgcctgagcaacatgtctctgaaaga
agccaggctctgcagcagacatcagctacagatatatcttcagcaggatctattagtgga
gatatcattgatgagttaatgtcttctgacgtgtttcctctcttaaggctttctcctacc
ccggcagatgactacaactttaatttagatgataacgaaggagtttgtgatctgtttgat
gtccagatactaaattattag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
Protein domain (4)   
   Pfam (4)   
All databases (50)   

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