KEGG   Homo sapiens (human): 1889Help
Entry
1889              CDS       T01001                                 

Gene name
ECE1, ECE
Definition
(RefSeq) endothelin converting enzyme 1
  KO
K01415  endothelin-converting enzyme [EC:3.4.24.71]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases [BR:hsa01002]
    1889 (ECE1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1889 (ECE1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.71  endothelin-converting enzyme 1
     1889 (ECE1)
Peptidases [BR:hsa01002]
 Metallo Peptidases
  Family M13: neprilysin family
   1889 (ECE1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   1889 (ECE1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Peptidase_M13_N Peptidase_M13 ImmE5
Motif
Other DBs
NCBI-GeneID: 1889
NCBI-ProteinID: NP_001388
OMIM: 600423
HGNC: 3146
Ensembl: ENSG00000117298
Vega: OTTHUMG00000002625
Pharos: P42892(Tchem)
UniProt: P42892 A0A024RAF7
Structure
PDB: 

Position
1p36.12
AA seq 770 aa AA seqDB search
MRGVWPPPVSALLSALGMSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHSPRSGQRCWA
ARTQVEKRLVVLVVLLAAGLVACLAALGIQYQTRSPSVCLSEACVSVTSSILSSMDPTVD
PCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASVSEAERKAQV
YYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVY
VSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAI
RPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVE
INESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEV
MYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLS
TLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNF
SWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGG
IGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVN
GRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTP
ESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW
NT seq 2313 nt NT seq  +upstreamnt  +downstreamnt
atgcggggcgtgtggccgcccccggtgtccgccctgctgtcggcgctggggatgtcgacg
tacaagcgggccacgctggacgaggaggacctggtggactcgctctccgagggcgacgca
taccccaacggcctgcaggtgaacttccacagcccccggagtggccagaggtgctgggct
gcacggacccaggtggagaagcggctggtggtgttggtggtacttctggcggcaggactg
gtggcctgcttggcagcactgggcatccagtaccagacaagatccccctctgtgtgcctg
agcgaagcttgtgtctcagtgaccagctccatcttgagctccatggaccccacagtggac
ccctgccatgacttcttcagctacgcctgtgggggctggatcaaggccaacccagtccct
gatggccactcacgctgggggaccttcagcaacctctgggaacacaaccaagcaatcatc
aagcacctcctcgaaaactccacggccagcgtgagcgaggcagagagaaaggcgcaagta
tactaccgtgcgtgcatgaacgagaccaggatcgaggagctcagggccaaacctctaatg
gagttgattgagaggctcgggggctggaacatcacaggtccctgggccaaggacaacttc
caggacaccctgcaggtggtcaccgcccactaccgcacctcacccttcttctctgtctat
gtcagtgccgattccaagaactccaacagcaacgtgatccaggtggaccagtctggcctg
ggcttgccctcgagagactattacctgaacaaaactgaaaacgagaaggtgctgaccgga
tatctgaactacatggtccagctggggaagctgctgggcggcggggacgaggaggccatc
cggccccagatgcagcagatcttggactttgagacggcactggccaacatcaccatccca
caggagaagcgccgtgatgaggagctcatctaccacaaagtgacggcagccgagctgcag
accttggcacccgccatcaactggttgccttttctcaacaccatcttctaccccgtggag
atcaatgaatccgagcctattgtggtctatgacaaggaataccttgagcagatctccact
ctcatcaacaccaccgacagatgcctgctcaacaactacatgatctggaacctggtgcgg
aaaacaagctccttccttgaccagcgctttcaggacgccgatgagaagttcatggaagtc
atgtacgggaccaagaagacctgtcttcctcgctggaagttttgcgtgagtgacacagaa
aacaacctgggctttgcgttgggccccatgtttgtcaaagcaaccttcgccgaggacagc
aagagcatagccaccgagatcatcctggagattaagaaggcatttgaggaaagcctgagc
accctgaagtggatggatgaggaaacccgaaaatcagccaaggaaaaggccgatgccatc
tacaacatgataggataccccaacttcatcatggatcccaaggagctggacaaagtgttt
aatgactacactgcagttccagacctctactttgaaaatgccatgcggtttttcaacttc
tcatggagggtcactgccgatcagctcaggaaagcccccaacagagatcagtggagcatg
accccgcccatggtgaacgcctactactcgcccaccaagaatgagattgtgtttccggcc
gggatcctgcaggcaccattctacacacgctcctcacccaaggccttaaactttggtggc
ataggtgtcgtcgtgggccatgagctgactcatgcttttgatgatcaaggacgggagtat
gacaaggacgggaacctccggccatggtggaagaactcatccgtggaggccttcaagcgt
cagaccgagtgcatggtagagcagtacagcaactacagcgtgaacggggagccggtgaac
gggcggcacaccctgggggagaacatcgccgacaacgggggtctcaaggcggcctatcgg
gcttaccagaactgggtgaagaagaacggggctgagcactcgctccccaccctgggcctc
accaataaccagctcttcttcctgggctttgcacaggtctggtgctccgtccgcacacct
gagagctcccacgaaggcctcatcaccgatccccacagcccctctcgcttccgggtcatc
ggctccctctccaattccaaggagttctcagaacacttccgctgcccacctggctcaccc
atgaacccgcctcacaagtgcgaagtctggtaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (3)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (65)   
   RefSeq(nuc) (7)   
   GenBank (29)   
   EMBL (29)   
Protein domain (3)   
   Pfam (3)   
All databases (109)   

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