KEGG   Homo sapiens (human): 1903
Entry
1903              CDS       T01001                                 
Symbol
S1PR3, C9orf108, C9orf47, EDG-3, EDG3, LPB3, S1P3, bA791O21.3
Name
(RefSeq) sphingosine-1-phosphate receptor 3
  KO
K04290  sphingosine 1-phosphate receptor 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04071  Sphingolipid signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Amiselimod (DG02399): D10904 D10905
Ozanimod (DG02827): D10967<JP/US> D10968
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    1903 (S1PR3)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1903 (S1PR3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1903 (S1PR3)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Sphingolipid
    1903 (S1PR3)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx Tetraspanin 7tm_4 DUF3325 YoqO
Other DBs
NCBI-GeneID: 1903
NCBI-ProteinID: NP_005217
OMIM: 601965
HGNC: 3167
Ensembl: ENSG00000213694
UniProt: Q99500
Structure
Position
9:88990863..89005155
AA seq 378 aa
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP
SSCIMDKNAALQNGIFCN
NT seq 1137 nt   +upstreamnt  +downstreamnt
atggcaactgccctcccgccgcgtctccagccggtgcgggggaacgagaccctgcgggag
cattaccagtacgtggggaagttggcgggcaggctgaaggaggcctccgagggcagcacg
ctcaccaccgtgctcttcttggtcatctgcagcttcatcgtcttggagaacctgatggtt
ttgattgccatctggaaaaacaataaatttcacaaccgcatgtactttttcattggcaac
ctggctctctgcgacctgctggccggcatcgcttacaaggtcaacattctgatgtctggc
aagaagacgttcagcctgtctcccacggtctggttcctcagggagggcagtatgttcgtg
gcccttggggcgtccacctgcagcttactggccatcgccatcgagcggcacttgacaatg
atcaaaatgaggccttacgacgccaacaagaggcaccgcgtcttcctcctgatcgggatg
tgctggctcattgccttcacgctgggcgccctgcccattctgggctggaactgcctgcac
aatctccctgactgctctaccatcctgcccctctactccaagaagtacattgccttctgc
atcagcatcttcacggccatcctggtgaccatcgtgatcctctacgcacgcatctacttc
ctggtgaagtccagcagccgtaaggtggccaaccacaacaactcggagcggtccatggca
ctgctgcggaccgtggtgattgtggtgagcgtgttcatcgcctgctggtccccactcttc
atcctcttcctcattgatgtggcctgcagggtgcaggcgtgccccatcctcttcaaggct
cagtggttcatcgtgttggctgtgctcaactccgccatgaacccggtcatctacacgctg
gccagcaaggagatgcggcgggccttcttccgtctggtctgcaactgcctggtcagggga
cggggggcccgcgcctcacccatccagcctgcgctcgacccaagcagaagtaaatcaagc
agcagcaacaatagcagccactctccgaaggtcaaggaagacctgccccacacagccccc
tcatcctgcatcatggacaagaacgcagcacttcagaatgggatcttctgcaactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (11)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (6)   
   GenBank (14)   
   EMBL (14)   
3D Structure (4)   
   PDB (4)   
Protein domain (6)   
   Pfam (6)   
All databases (60)   

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