KEGG   Homo sapiens (human): 1903
Entry
1903              CDS       T01001                                 

Gene name
S1PR3, EDG-3, EDG3, LPB3, S1P3
Definition
(RefSeq) sphingosine-1-phosphate receptor 3
  KO
K04290  sphingosine 1-phosphate receptor 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04071  Sphingolipid signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Amiselimod (DG02399): D10904 D10905
Etrasimod (DG02444): D10930
Ozanimod (DG02827): D10967<US> D10968
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    1903 (S1PR3)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1903 (S1PR3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    1903 (S1PR3)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Sphingolipid
    1903 (S1PR3)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx Tetraspanin 7tm_4 YoqO
Other DBs
NCBI-GeneID: 1903
NCBI-ProteinID: NP_005217
OMIM: 601965
HGNC: 3167
Ensembl: ENSG00000213694
Vega: OTTHUMG00000020173
Pharos: Q99500(Tclin)
UniProt: Q99500
Position
9q22.1
AA seq 378 aa
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP
SSCIMDKNAALQNGIFCN
NT seq 1137 nt   +upstreamnt  +downstreamnt
atggcaactgccctcccgccgcgtctccagccggtgcgggggaacgagaccctgcgggag
cattaccagtacgtggggaagttggcgggcaggctgaaggaggcctccgagggcagcacg
ctcaccaccgtgctcttcttggtcatctgcagcttcatcgtcttggagaacctgatggtt
ttgattgccatctggaaaaacaataaatttcacaaccgcatgtactttttcattggcaac
ctggctctctgcgacctgctggccggcatcgcttacaaggtcaacattctgatgtctggc
aagaagacgttcagcctgtctcccacggtctggttcctcagggagggcagtatgttcgtg
gcccttggggcgtccacctgcagcttactggccatcgccatcgagcggcacttgacaatg
atcaaaatgaggccttacgacgccaacaagaggcaccgcgtcttcctcctgatcgggatg
tgctggctcattgccttcacgctgggcgccctgcccattctgggctggaactgcctgcac
aatctccctgactgctctaccatcctgcccctctactccaagaagtacattgccttctgc
atcagcatcttcacggccatcctggtgaccatcgtgatcctctacgcacgcatctacttc
ctggtgaagtccagcagccgtaaggtggccaaccacaacaactcggagcggtccatggca
ctgctgcggaccgtggtgattgtggtgagcgtgttcatcgcctgctggtccccactcttc
atcctcttcctcattgatgtggcctgcagggtgcaggcgtgccccatcctcttcaaggct
cagtggttcatcgtgttggctgtgctcaactccgccatgaacccggtcatctacacgctg
gccagcaaggagatgcggcgggccttcttccgtctggtctgcaactgcctggtcagggga
cggggggcccgcgcctcacccatccagcctgcgctcgacccaagcagaagtaaatcaagc
agcagcaacaatagcagccactctccgaaggtcaaggaagacctgccccacacagccccc
tcatcctgcatcatggacaagaacgcagcacttcagaatgggatcttctgcaactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (5)   
   KEGG DRUG (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (5)   
   Pfam (5)   
All databases (50)   

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