KEGG   Homo sapiens (human): 191Help
Entry
191               CDS       T01001                                 

Gene name
AHCY, SAHH, adoHcyase
Definition
(RefSeq) adenosylhomocysteinase
  KO
K01251  adenosylhomocysteinase [EC:3.3.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00270  Cysteine and methionine metabolism
hsa01100  Metabolic pathways
Module
hsa_M00035  Methionine degradation
Disease
H00184  Hypermethioninemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    191 (AHCY)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    191 (AHCY)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    191 (AHCY)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.1  Thioether and trialkylsulfonium hydrolases
    3.3.1.1  adenosylhomocysteinase
     191 (AHCY)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     191 (AHCY)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   191 (AHCY)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AdoHcyase AdoHcyase_NAD 2-Hacid_dh_C IlvN TrkA_N 3HCDH_N
Motif
Other DBs
NCBI-GeneID: 191
NCBI-ProteinID: NP_000678
OMIM: 180960
HGNC: 343
Ensembl: ENSG00000101444
Vega: OTTHUMG00000140098
Pharos: P23526(Tchem)
UniProt: P23526 A0A384MTQ3
Structure
PDB: 

Position
20q11.22
AA seq 432 aa AA seqDB search
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET
AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF
KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
CDGPFKPDHYRY
NT seq 1299 nt NT seq  +upstreamnt  +downstreamnt
atgtctgacaaactgccctacaaagtcgccgacatcggcctggctgcctggggacgcaag
gccctggacattgctgagaacgagatgccgggcctgatgcgtatgcgggagcggtactcg
gcctccaagccactgaagggcgcccgcatcgctggctgcctgcacatgaccgtggagacg
gccgtcctcattgagaccctcgtcaccctgggtgctgaggtgcagtggtccagctgcaac
atcttctccacccaggaccatgcggcggctgccattgccaaggctggcattccggtgtat
gcctggaagggcgaaacggacgaggagtacctgtggtgcattgagcagaccctgtacttc
aaggacgggcccctcaacatgattctggacgacgggggcgacctcaccaacctcatccac
accaagtacccgcagcttctgccaggcatccgaggcatctctgaggagaccacgactggg
gtccacaacctctacaagatgatggccaatgggatcctcaaggtgcctgccatcaatgtc
aatgactccgtcaccaagagcaagtttgacaacctctatggctgccgggagtccctcata
gatggcatcaagcgggccacagatgtgatgattgccggcaaggtagcggtggtagcaggc
tatggtgatgtgggcaagggctgtgcccaggccctgcggggtttcggagcccgcgtcatc
atcaccgagattgaccccatcaacgcactgcaggctgccatggagggctatgaggtgacc
accatggatgaggcctgtcaggagggcaacatctttgtcaccaccacaggctgtattgac
atcatccttggccggcactttgagcagatgaaggatgatgccattgtgtgtaacattgga
cactttgacgtggagatcgatgtcaagtggctcaacgagaacgccgtggagaaggtgaac
atcaagccgcaggtggaccggtatcggttgaagaatgggcgccgcatcatcctgctggcc
gagggtcggctggtcaacctgggttgtgccatgggccaccccagcttcgtgatgagtaac
tccttcaccaaccaggtgatggcgcagatcgagctgtggacccatccagacaagtacccc
gttggggttcatttcctgcccaagaagctggatgaggcagtggctgaagcccacctgggc
aagctgaatgtgaagttgaccaagctaactgagaagcaagcccagtacctgggcatgtcc
tgtgatggccccttcaagccggatcactaccgctactga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (60)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (27)   
   OC (1)   
   PHAROS (1)   
   PROTHERM (10)   
   VEGA (1)   
Protein sequence (16)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (51)   
   RefSeq(nuc) (13)   
   GenBank (19)   
   EMBL (19)   
Protein domain (6)   
   Pfam (6)   
All databases (153)   

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