KEGG   Homo sapiens (human): 1915
Entry
1915              CDS       T01001                                 
Symbol
EEF1A1, CCS-3, CCS3, EE1A1, EEF-1, EEF1A, EF-Tu, EF1A, EF1A1, EF1alpha1, GRAF-1EF, LENG7, PTI1, eEF1A-1
Name
(RefSeq) eukaryotic translation elongation factor 1 alpha 1
  KO
K03231  elongation factor 1-alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa05134  Legionellosis
hsa05140  Leishmaniasis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    1915 (EEF1A1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05134 Legionellosis
    1915 (EEF1A1)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    1915 (EEF1A1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    1915 (EEF1A1)
   03016 Transfer RNA biogenesis [BR:hsa03016]
    1915 (EEF1A1)
   03012 Translation factors [BR:hsa03012]
    1915 (EEF1A1)
   04131 Membrane trafficking [BR:hsa04131]
    1915 (EEF1A1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1915 (EEF1A1)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Factors involved in mRNA localization
    Trans-acting binding proteins
     1915 (EEF1A1)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic type
  tRNA transport factors
   tRNA export factors
    1915 (EEF1A1)
Translation factors [BR:hsa03012]
 Eukaryotic type
  Elongation factors
   1915 (EEF1A1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Other CMA associated proteins
    1915 (EEF1A1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   1915 (EEF1A1)
SSDB
Motif
Pfam: GTP_EFTU GTP-eEF1A_C GTP_EFTU_D3 GTP_EFTU_D2 MMR_HSR1 GTP_EFTU_D4
Other DBs
NCBI-GeneID: 1915
NCBI-ProteinID: NP_001393
OMIM: 130590
HGNC: 3189
Ensembl: ENSG00000156508
UniProt: P68104 Q6IPS9
Structure
Position
6:complement(73515750..73521032)
AA seq 462 aa
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL
DKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV
GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKK
IGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTR
PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALS
EALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPV
LDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPP
LGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK
NT seq 1389 nt   +upstreamnt  +downstreamnt
atgggaaaggaaaagactcatatcaacattgtcgtcattggacacgtagattcgggcaag
tccaccactactggccatctgatctataaatgcggtggcatcgacaaaagaaccattgaa
aaatttgagaaggaggctgctgagatgggaaagggctccttcaagtatgcctgggtcttg
gataaactgaaagctgagcgtgaacgtggtatcaccattgatatctccttgtggaaattt
gagaccagcaagtactatgtgactatcattgatgccccaggacacagagactttatcaaa
aacatgattacagggacatctcaggctgactgtgctgtcctgattgttgctgctggtgtt
ggtgaatttgaagctggtatctccaagaatgggcagacccgagagcatgcccttctggct
tacacactgggtgtgaaacaactaattgtcggtgttaacaaaatggattccactgagcca
ccctacagccagaagagatatgaggaaattgttaaggaagtcagcacttacattaagaaa
attggctacaaccccgacacagtagcatttgtgccaatttctggttggaatggtgacaac
atgctggagccaagtgctaacatgccttggttcaagggatggaaagtcacccgtaaggat
ggcaatgccagtggaaccacgctgcttgaggctctggactgcatcctaccaccaactcgt
ccaactgacaagcccttgcgcctgcctctccaggatgtctacaaaattggtggtattggt
actgttcctgttggccgagtggagactggtgttctcaaacccggtatggtggtcaccttt
gctccagtcaacgttacaacggaagtaaaatctgtcgaaatgcaccatgaagctttgagt
gaagctcttcctggggacaatgtgggcttcaatgtcaagaatgtgtctgtcaaggatgtt
cgtcgtggcaacgttgctggtgacagcaaaaatgacccaccaatggaagcagctggcttc
actgctcaggtgattatcctgaaccatccaggccaaataagcgccggctatgcccctgta
ttggattgccacacggctcacattgcatgcaagtttgctgagctgaaggaaaagattgat
cgccgttctggtaaaaagctggaagatggccctaaattcttgaagtctggtgatgctgcc
attgttgatatggttcctggcaagcccatgtgtgttgagagcttctcagactatccacct
ttgggtcgctttgctgttcgtgatatgagacagacagttgcggtgggtgtcatcaaagca
gtggacaagaaggctgctggagctggcaaggtcaccaagtctgcccagaaagctcagaag
gctaaatga

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (422)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (398)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (167)   
   RefSeq(nuc) (3)   
   GenBank (82)   
   EMBL (82)   
3D Structure (4)   
   PDB (4)   
Protein domain (6)   
   Pfam (6)   
All databases (615)   

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