KEGG   Homo sapiens (human): 2028
Entry
2028              CDS       T01001                                 
Symbol
ENPEP, APA, CD249, gp160
Name
(RefSeq) glutamyl aminopeptidase
  KO
K11141  glutamyl aminopeptidase [EC:3.4.11.7]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04614  Renin-angiotensin system
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04614 Renin-angiotensin system
    2028 (ENPEP)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    2028 (ENPEP)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2028 (ENPEP)
   04090 CD molecules [BR:hsa04090]
    2028 (ENPEP)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.11  Aminopeptidases
    3.4.11.7  glutamyl aminopeptidase
     2028 (ENPEP)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M1
   2028 (ENPEP)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2028 (ENPEP)
CD molecules [BR:hsa04090]
 Proteins
  2028 (ENPEP)
SSDB
Motif
Pfam: Peptidase_M1 ERAP1_C Peptidase_M1_N Cyclophil_like DUF1570
Other DBs
NCBI-GeneID: 2028
NCBI-ProteinID: NP_001968
OMIM: 138297
HGNC: 3355
Ensembl: ENSG00000138792
Pharos: Q07075(Tchem)
UniProt: Q07075
Structure
Position
4:110476155..110565285
AA seq 957 aa
MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPSHL
PSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVS
ISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPS
SGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGQVKSIVATDHEPTDARKSFPCFDEPNKK
ATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRI
SNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAME
NWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFAS
FFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYS
KGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTR
QMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSE
KEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLID
DAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYF
QGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPV
NLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLK
DTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFN
TELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG
NT seq 2874 nt   +upstreamnt  +downstreamnt
atgaactttgcggagagagagggctctaagagatactgcattcaaacgaaacatgtggcc
attctctgtgcggtggtggtgggtgtaggattaatagtgggacttgccgtgggcttgacc
agatcgtgtgactccagcggggacggcgggccgggcactgcgccagctccttcccacctg
ccttcttccacggccagcccctcaggtcctcctgcccaggaccaggacatctgcccggcc
agtgaggatgagagcggacagtggaaaaactttcgactgccggacttcgtcaacccagtc
cactacgacctgcacgtgaagcccctgttggaggaggacacctacacgggcaccgtgagc
atctccatcaacctgagcgctcccacccggtacctgtggctgcacctccgggagaccagg
atcacccggctcccggagctgaagaggccctctggggaccaggtgcaagtccggaggtgt
ttcgagtacaaaaagcaggagtacgtggtggtcgaggcggaggaagagcttacccccagc
agtggagatggcctgtatctcctgaccatggagttcgccggctggctgaacggctccctc
gtgggattttatagaaccacctacacggagaacggacaagtcaagagcatagtggccacc
gatcatgaaccaacagatgccaggaaatcttttccttgttttgatgagcccaacaaaaag
gcaacttatacaatatctatcacccatcccaaagaatacggagcactttcaaatatgcca
gtggcgaaagaagagtcagtggatgataaatggactcgaacaacttttgagaagtctgtc
cccatgagcacgtacctggtgtgctttgctgtacatcaatttgactctgtaaagagaata
tcaaatagtggaaaacctcttacaatttatgtccagccagagcaaaagcacacagccgaa
tatgctgcaaacataactaaaagtgtgtttgattattttgaagaatactttgctatgaat
tattctcttcctaaattagataaaatcgctattccagattttggcactggtgccatggag
aactggggactcatcacgtacagagaaacgaacctgctttatgaccctaaggaatcagcc
tcatcaaaccaacagagggtggccactgtggttgcccatgaacttgtgcatcagtggttt
ggaaatattgtgaccatggactggtgggaagacttgtggctaaatgaaggatttgcttct
ttctttgagtttctgggagtaaaccatgcagaaacagactggcaaatgcgtgaccaaatg
ttacttgaagatgtattacctgttcaagaggatgattctttgatgtcttcgcatccaatt
attgtgactgtgacaacccctgatgaaataacatctgtttttgatggaatatcctatagc
aagggatcttctattttgagaatgcttgaagactggataaaaccagagaattttcaaaaa
ggatgtcagatgtacttggaaaaataccaattcaagaatgcaaaaacttctgatttttgg
gcagcactggaagaggcaagtaggctaccagtgaaagaagtaatggacacctggaccaga
cagatgggttatcctgtgcttaacgtgaacggtgtcaagaacatcacacagaaacgcttt
ttgttggacccaagagctaacccttctcagcccccttcagatcttggttatacatggaat
atcccagttaaatggactgaagataatataacaagcagtgtgttatttaataggtcagaa
aaagaaggaatcactttgaactcctctaatcctagtggaaatgcttttctcaaaataaac
ccagatcatattgggttttatcgtgtaaattatgaagtagcaacttgggactcgatagct
acagcgctctccttgaaccacaagacattttcttcagcagatcgtgcaagtcttattgat
gatgcttttgccttggcaagagctcaacttctagattataaggtggctttgaacttgacc
aagtatctcaaaagggaagagaattttttaccatggcagagagtaatttcagctgtaacc
tacatcattagcatgtttgaagatgataaagagctatatcctatgattgaggaatacttc
caaggtcaagtgaagcctattgcagattctctgggatggaatgatgctggagaccatgtc
acaaagttactccgttcctccgtgttagggtttgcgtgcaagatgggagacagagaagcc
ttgaacaatgcttcctcgttatttgagcagtggctaaatgggactgtaagccttcccgta
aatctcaggcttctggtgtatcggtatgggatgcagaactctggcaatgagatttcatgg
aactacactcttgagcaataccagaaaacttcattagctcaagaaaaagaaaaactgctg
tatggattagcatcagtgaagaacgttactcttttgtcaaggtatttggatttgctcaag
gacacgaaccttattaaaactcaggatgtgtttacagtcattcgatatatctcatataac
agctatgggaagaacatggcctggaattggatacaactcaactgggactatctagtcaac
agatatacactcaataacagaaaccttggccgaattgtcacaatagcagagccattcaac
actgaactgcaactgtggcagatggagagcttttttgcaaaatatccacaagctggagca
ggagaaaaacctagggaacaagtgctggaaacagtgaaaaacaatatagagtggctaaaa
caacatagaaacaccatcagagaatggttttttaatttacttgagagtggttaa

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (47)   
   RefSeq(nuc) (7)   
   GenBank (20)   
   EMBL (20)   
3D Structure (7)   
   PDB (7)   
Protein domain (5)   
   Pfam (5)   
All databases (98)   

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