KEGG   Homo sapiens (human): 204851
Entry
204851            CDS       T01001                                 
Symbol
HIPK1, Myak, Nbak2
Name
(RefSeq) homeodomain interacting protein kinase 1
  KO
K08826  homeodomain interacting protein kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    204851 (HIPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    204851 (HIPK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     204851 (HIPK1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   204851 (HIPK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo Pkinase_fungal APH Pox_ser-thr_kin TCAD9 GP24_25
Other DBs
NCBI-GeneID: 204851
NCBI-ProteinID: NP_938009
OMIM: 608003
HGNC: 19006
Ensembl: ENSG00000163349
UniProt: Q86Z02 B4DZ33
Position
1:113929324..113977869
AA seq 1210 aa
MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQANSSH
QVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHRSNVSLLEPYQK
CGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSSSGEGDYQLVQH
EILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSR
LSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVA
TALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRA
PEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGT
KTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTD
MLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHSNHVKSCFQNME
ICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVLASSSTAAAATL
SLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQ
TGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATIT
PQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVALHNSVQPTAMI
PEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSS
LPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQHQPIIIPDTPS
PPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSLSSPYSTDTLSA
LRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSNKTKPVASVSGQ
SSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRRQQAFVAPLSQA
PYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSIAHLFSPQGSSR
HAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSRGSTIYTGYPLS
PTKISQYSYL
NT seq 3633 nt   +upstreamnt  +downstreamnt
atggcatcacagctgcaagtgttttcgcccccatcagtgtcgtcgagtgccttctgcagt
gcgaagaaactgaaaatagagccctctggctgggatgtttcaggacagagtagcaacgac
aaatattatacccacagcaaaaccctcccagccacacaagggcaagccaactcctctcac
caggtagcaaatttcaacatccctgcttacgaccagggcctcctcctcccagctcctgca
gtggagcatattgttgtaacagccgctgatagctcgggcagtgctgctacatcaaccttc
caaagcagccagaccctgactcacagaagcaacgtttctttgcttgagccatatcaaaaa
tgtggattgaaacgaaaaagtgaggaagttgacagcaacggtagtgtgcagatcatagaa
gaacatccccctctcatgctgcaaaacaggactgtggtgggtgctgctgccacaaccacc
actgtgaccacaaagagtagcagttccagcggagaaggggattaccagctggtccagcat
gagatcctttgctctatgaccaatagctatgaagtcttggagttcctaggccgggggaca
tttggacaggtggctaagtgctggaagaggagcaccaaggaaattgtggctattaaaatc
ttgaagaaccacccctcctatgccagacaaggacagattgaagtgagcatcctttcccgc
ctaagcagtgaaaatgctgatgagtataattttgtccgttcatacgagtgctttcagcat
aagaatcacacctgccttgtttttgaaatgttggagcagaacttatatgattttctaaag
caaaacaaatttagcccactgccactcaagtacatcagaccaatcttgcagcaggtggcc
acagccttgatgaagctcaagagtcttggtctgatccacgctgaccttaagcctgaaaac
atcatgctggttgatccagttcgccagccctaccgagtgaaggtcattgactttggttct
gctagtcacgtttccaaagctgtgtgctcaacctacttacagtcacgttactacagagct
cctgaaattattcttgggttaccattttgtgaagctattgatatgtggtcactgggctgt
gtgatagctgagctgttcctgggatggcctctttatcctggtgcttcagaatatgatcag
attcgttatatttcacaaacacaaggcttgccagctgaatatcttctcagtgccggaaca
aaaacaaccaggtttttcaacagagatcctaatttggggtacccactgtggaggcttaag
acacctgaagaacatgaactggagactggaataaaatcaaaagaagctcggaagtacatt
tttaattgcttagatgacatggctcaggtgaatatgtctacagacctggagggaacagac
atgttggcagagaaggcagaccgaagagaatacattgatctgttaaagaaaatgctcaca
attgatgcagataagagaattacccctctaaaaactcttaaccatcagtttgtgacaatg
actcaccttttggattttccacatagcaatcatgttaagtcttgttttcagaacatggag
atctgcaagcggagggttcacatgtatgatacagtgagtcagatcaagagtcccttcact
acacatgttgccccaaatacaagcacaaatctaaccatgagcttcagcaatcagctcaat
acagtgcacaatcaggccagtgttctagcttccagttctactgcagcagctgctactctt
tctctggctaattcagatgtctcactactaaactaccagtcagctttgtacccatcatct
gctgcaccagttcctggagttgcccagcagggtgtttccttgcagcctggaaccacccag
atttgcactcagacagatccattccaacagacatttatagtatgtccacctgcgtttcaa
actggactacaagcaacaacaaagcattctggattccctgtgaggatggataatgctgta
ccgattgtaccccaggcaccagctgctcagccactacagattcagtcaggagttctcacg
cagggaagctgtacaccactaatggtagcaactctccaccctcaagtagccaccatcaca
ccgcagtatgcggtgccctttactctgagctgcgcagccggccggccggcgctggttgaa
cagactgccgctgtactgcaggcgtggcctggagggactcagcaaattctcctgccttca
acttggcaacagttgcctggggtagctctacacaactctgtccagcccacagcaatgatt
ccagaggccatggggagtggacagcagctagctgactggaggaatgcccactctcatggc
aaccagtacagcactatcatgcagcagccatccttgctgactaaccatgtgacattggcc
actgctcagcctctgaatgttggtgttgcccatgttgtcagacaacaacaatccagttcc
ctcccttcgaagaagaataagcagtcagctccagtctcttccaagtcctctctagatgtt
ctgccttcccaagtctattctctggttgggagcagtcccctccgcaccacatcttcttat
aattccttggtccctgtccaagatcagcatcagcccatcatcattccagatactcccagc
cctcctgtgagtgtcatcactatccgaagtgacactgatgaggaagaggacaacaaatac
aagcccagtagctctggactgaagccaaggtctaatgtcatcagttatgtcactgtcaat
gattctccagactctgactcttctttgagcagcccttattccactgataccctgagtgct
ctccgaggcaatagtggatccgttttggaggggcctggcagagttgtggcagatggcact
ggcacccgcactatcattgtgcctccactgaaaactcagcttggtgactgcactgtagca
acccaggcctcaggtctcctgagcaataagactaagccagtcgcttcagtgagtgggcag
tcatctggatgctgtatcacccccacagggtatcgagctcaacgcggggggaccagtgca
gcacaaccactcaatcttagccagaaccagcagtcatcggcggctccaacctcacaggag
agaagcagcaacccagccccccgcaggcagcaggcgtttgtggcccctctctcccaagcc
ccctacaccttccagcatggcagcccgctacactcgacagggcacccacaccttgccccg
gcccctgctcacctgccaagccaggctcatctgtatacgtatgctgccccgacttctgct
gctgcactgggctcaaccagctccattgctcatcttttctccccacagggttcctcaagg
catgctgcagcctataccactcaccctagcactttggtgcaccaggtccctgtcagtgtt
gggcccagcctcctcacttctgccagcgtggcccctgctcagtaccaacaccagtttgcc
acccaatcctacattgggtcttcccgaggctcaacaatttacactggatacccgctgagt
cctaccaagatcagccagtattcctacttatag

  All links  
Disease (1)   
   OMIM (1)   
Gene (24)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (29)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (26)   
DNA sequence (48)   
   RefSeq(nuc) (26)   
   GenBank (11)   
   EMBL (11)   
Protein domain (8)   
   Pfam (8)   
All databases (110)   

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