KEGG   Homo sapiens (human): 2078
Entry
2078              CDS       T01001                                 
Symbol
ERG, LMPHM14, erg-3, p55
Name
(RefSeq) transcriptional regulator ERG isoform 1
  KO
K09435  transcriptional regulator ERG
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
hsa05215  Prostate cancer
Network
nt06240  Transcription (cancer)
nt06272  Prostate cancer
  Element
N00128  TMPRSS2-ERG fusion to transcriptional activation
N00129  TMPRSS2-ERG fusion to transcriptional repression
N00135  EWSR1-ERG fusion to transcriptional activation
Disease
H00024  Prostate cancer
H00035  Ewing sarcoma
H00535  Lymphatic malformation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    2078 (ERG)
  09162 Cancer: specific types
   05215 Prostate cancer
    2078 (ERG)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2078 (ERG)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters Ets-type
    2078 (ERG)
SSDB
Motif
Pfam: Ets SAM_PNT SAM_3 Arb2-like
Other DBs
NCBI-GeneID: 2078
NCBI-ProteinID: NP_891548
OMIM: 165080
HGNC: 3446
Ensembl: ENSP00000288319.7
UniProt: P11308
Structure
Position
21:complement(38367261..38661783)
AA seq 479 aa
MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQP
PARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTT
NERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLT
PSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEA
TQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTS
SRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNM
NYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGS
YHAHPQKMNFVAPHPPALPVTSSSFFAAPNPYWNSPTGGIYPNTRLPTSHMPSHLGTYY
NT seq 1440 nt   +upstreamnt  +downstreamnt
atggccagcactattaaggaagccttatcagttgtgagtgaggaccagtcgttgtttgag
tgtgcctacggaacgccacacctggctaagacagagatgaccgcgtcctcctccagcgac
tatggacagacttccaagatgagcccacgcgtccctcagcaggattggctgtctcaaccc
ccagccagggtcaccatcaaaatggaatgtaaccctagccaggtgaatggctcaaggaac
tctcctgatgaatgcagtgtggccaaaggcgggaagatggtgggcagcccagacaccgtt
gggatgaactacggcagctacatggaggagaagcacatgccacccccaaacatgaccacg
aacgagcgcagagttatcgtgccagcagatcctacgctatggagtacagaccatgtgcgg
cagtggctggagtgggcggtgaaagaatatggccttccagacgtcaacatcttgttattc
cagaacatcgatgggaaggaactgtgcaagatgaccaaggacgacttccagaggctcacc
cccagctacaacgccgacatccttctctcacatctccactacctcagagagactcctctt
ccacatttgacttcagatgatgttgataaagccttacaaaactctccacggttaatgcat
gctagaaacacagggggtgcagcttttattttcccaaatacttcagtatatcctgaagct
acgcaaagaattacaactaggccagatttaccatatgagccccccaggagatcagcctgg
accggtcacggccaccccacgccccagtcgaaagctgctcaaccatctccttccacagtg
cccaaaactgaagaccagcgtcctcagttagatccttatcagattcttggaccaacaagt
agccgccttgcaaatccaggcagtggccagatccagctttggcagttcctcctggagctc
ctgtcggacagctccaactccagctgcatcacctgggaaggcaccaacggggagttcaag
atgacggatcccgacgaggtggcccggcgctggggagagcggaagagcaaacccaacatg
aactacgataagctcagccgcgccctccgttactactatgacaagaacatcatgaccaag
gtccatgggaagcgctacgcctacaagttcgacttccacgggatcgcccaggccctccag
ccccaccccccggagtcatctctgtacaagtacccctcagacctcccgtacatgggctcc
tatcacgcccacccacagaagatgaactttgtggcgccccaccctccagccctccccgtg
acatcttccagtttttttgctgccccaaacccatactggaattcaccaactgggggtata
taccccaacactaggctccccaccagccatatgccttctcatctgggcacttactactaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (10)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (65)   
   RefSeq(nuc) (11)   
   GenBank (27)   
   EMBL (27)   
3D Structure (8)   
   PDB (8)   
Protein domain (4)   
   Pfam (4)   
All databases (100)   

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