KEGG   Homo sapiens (human): 2191Help
Entry
2191              CDS       T01001                                 

Gene name
FAP, DPPIV, FAPA, FAPalpha, SIMP
Definition
(RefSeq) fibroblast activation protein alpha
  KO
K08674  fibroblast activation protein, alpha [EC:3.4.21.-]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    2191 (FAP)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.-  
     2191 (FAP)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S9: prolyl oligopeptidase family
   2191 (FAP)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DPPIV_N Peptidase_S9 DPPIV_rep LIP DLH Abhydrolase_6 Esterase_phd Peptidase_S15 AXE1 PAF-AH_p_II DUF2920
Motif
Other DBs
NCBI-GeneID: 2191
NCBI-ProteinID: NP_004451
OMIM: 600403
HGNC: 3590
Ensembl: ENSG00000078098
Vega: OTTHUMG00000153890
Pharos: Q12884(Tchem)
UniProt: Q12884
Structure
PDB: 

Position
2q24.2
AA seq 760 aa AA seqDB search
MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN
WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK
LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP
FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG
DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT
DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD
AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG
RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR
TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV
YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ
ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY
TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA
QVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD
NT seq 2283 nt NT seq  +upstreamnt  +downstreamnt
atgaagacttgggtaaaaatcgtatttggagttgccacctctgctgtgcttgccttattg
gtgatgtgcattgtcttacgcccttcaagagttcataactctgaagaaaatacaatgaga
gcactcacactgaaggatattttaaatggaacattttcttataaaacattttttccaaac
tggatttcaggacaagaatatcttcatcaatctgcagataacaatatagtactttataat
attgaaacaggacaatcatataccattttgagtaatagaaccatgaaaagtgtgaatgct
tcaaattacggcttatcacctgatcggcaatttgtatatctagaaagtgattattcaaag
ctttggagatactcttacacagcaacatattacatctatgaccttagcaatggagaattt
gtaagaggaaatgagcttcctcgtccaattcagtatttatgctggtcgcctgttgggagt
aaattagcatatgtctatcaaaacaatatctatttgaaacaaagaccaggagatccacct
tttcaaataacatttaatggaagagaaaataaaatatttaatggaatcccagactgggtt
tatgaagaggaaatgcttgctacaaaatatgctctctggtggtctcctaatggaaaattt
ttggcatatgcggaatttaatgatacggatataccagttattgcctattcctattatggc
gatgaacaatatcctagaacaataaatattccatacccaaaggctggagctaagaatccc
gttgttcggatatttattatcgataccacttaccctgcgtatgtaggtccccaggaagtg
cctgttccagcaatgatagcctcaagtgattattatttcagttggctcacgtgggttact
gatgaacgagtatgtttgcagtggctaaaaagagtccagaatgtttcggtcctgtctata
tgtgacttcagggaagactggcagacatgggattgtccaaagacccaggagcatatagaa
gaaagcagaactggatgggctggtggattctttgtttcaacaccagttttcagctatgat
gccatttcgtactacaaaatatttagtgacaaggatggctacaaacatattcactatatc
aaagacactgtggaaaatgctattcaaattacaagtggcaagtgggaggccataaatata
ttcagagtaacacaggattcactgttttattctagcaatgaatttgaagaataccctgga
agaagaaacatctacagaattagcattggaagctatcctccaagcaagaagtgtgttact
tgccatctaaggaaagaaaggtgccaatattacacagcaagtttcagcgactacgccaag
tactatgcacttgtctgctacggcccaggcatccccatttccacccttcatgatggacgc
actgatcaagaaattaaaatcctggaagaaaacaaggaattggaaaatgctttgaaaaat
atccagctgcctaaagaggaaattaagaaacttgaagtagatgaaattactttatggtac
aagatgattcttcctcctcaatttgacagatcaaagaagtatcccttgctaattcaagtg
tatggtggtccctgcagtcagagtgtaaggtctgtatttgctgttaattggatatcttat
cttgcaagtaaggaagggatggtcattgccttggtggatggtcgaggaacagctttccaa
ggtgacaaactcctctatgcagtgtatcgaaagctgggtgtttatgaagttgaagaccag
attacagctgtcagaaaattcatagaaatgggtttcattgatgaaaaaagaatagccata
tggggctggtcctatggaggatacgtttcatcactggcccttgcatctggaactggtctt
ttcaaatgtggtatagcagtggctccagtctccagctgggaatattacgcgtctgtctac
acagagagattcatgggtctcccaacaaaggatgataatcttgagcactataagaattca
actgtgatggcaagagcagaatatttcagaaatgtagactatcttctcatccacggaaca
gcagatgataatgtgcactttcaaaactcagcacagattgctaaagctctggttaatgca
caagtggatttccaggcaatgtggtactctgaccagaaccacggcttatccggcctgtcc
acgaaccacttatacacccacatgacccacttcctaaagcagtgtttctctttgtcagac
taa

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (29)   
   RefSeq(nuc) (7)   
   GenBank (11)   
   EMBL (11)   
Protein domain (11)   
   Pfam (11)   
All databases (71)   

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