KEGG   Homo sapiens (human): 2193
Entry
2193              CDS       T01001                                 
Symbol
FARSA, CML33, FARSL, FARSLA, FRSA, PheHA, RILDBC2
Name
(RefSeq) phenylalanyl-tRNA synthetase subunit alpha
  KO
K01889  phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00970  Aminoacyl-tRNA biosynthesis
Disease
H02466  Rajab interstitial lung disease with brain calcification
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   00970 Aminoacyl-tRNA biosynthesis
    2193 (FARSA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    2193 (FARSA)
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:hsa03016]
    2193 (FARSA)
Enzymes [BR:hsa01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.20  phenylalanine---tRNA ligase
     2193 (FARSA)
Amino acid related enzymes [BR:hsa01007]
 Aminoacyl-tRNA synthetase
  Class II (U)
   2193 (FARSA)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Other AARSs
    2193 (FARSA)
 Prokaryotic type
    2193 (FARSA)
SSDB
Motif
Pfam: tRNA-synt_2d PheRS_DBD1 PheRS_DBD3 PheRS_DBD2 MarR_2 tRNA_synthFbeta tRNA-synt_2 HTH_11 DUF1204 ARM_FBXO47
Other DBs
NCBI-GeneID: 2193
NCBI-ProteinID: NP_004452
OMIM: 602918
HGNC: 3592
Ensembl: ENSG00000179115
UniProt: Q9Y285 Q6IBR2
Structure
Position
19:complement(12922479..12933711)
AA seq 508 aa
MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKH
WELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAA
DGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSA
FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE
MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH
SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE
TLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVF
SYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGH
KVNLQMVYDSPLCRLDAEPRPPPTQEAA
NT seq 1527 nt   +upstreamnt  +downstreamnt
atggcggatggtcaggtggcggaactgctgctccggcggctggaggcgtctgatggcggc
ctggacagcgccgagttggcggctgagctgggcatggagcaccaggcggtggtgggcgcc
gtgaagagccttcaggcgctgggcgaggtcatcgaggctgaacttcggtccaccaagcac
tgggagcttactgcggagggcgaggagattgcccgggagggcagccatgaggcccgtgtg
tttcgaagcattcccccagagggcctggcccagagcgagcttatgcgactgcccagtggc
aaagtgggcttcagcaaggccatgtccaacaagtggattcgggtggacaagagtgcggct
gacgggccccgggtgttccgagtggtggacagcatggaggatgaggtgcagcggcggctc
cagctggtccgggggggacaggctgagaagctgggggagaaggagaggagcgagctgagg
aagaggaagctgttggctgaagtgactctgaagacctactgggtgagcaaaggcagtgcc
tttagtaccagcatctccaagcaagagacagagctgagcccagagatgatctccagtggc
tcttggcgggaccggcccttcaagccctacaacttcttggcccacggtgtcctccccgac
agcggccaccttcacccgctgctcaaggtccgctcccagttccgacagatcttcctggag
atggggttcaccgagatgccgactgataacttcattgagagctccttctggaactttgac
gccctcttccagccccagcagcacccagcccgtgaccagcacgacaccttcttccttcga
gatccagcggaggccctgcagctcccaatggactatgtccagcgggtcaagcggacccac
tctcagggcggctacggctcacaggggtacaagtataactggaagctggacgaggcccgg
aaaaacctactgcgaacccacaccacatcagccagcgcccgtgcgctctaccgccttgcc
cagaagaagcccttcactccggtcaagtacttctccatcgaccgcgtattccggaatgag
accctggacgccacgcacctggctgagttccaccagatcgagggcgtggtggcggatcat
ggtctcaccttgggccacctcatgggcgttctgcgggagttcttcaccaagctgggtatc
acgcaactccgcttcaagccagcctacaacccatacacagagcccagcatggaggtgttc
agctaccaccaaggcctgaagaagtgggtggaggtcggaaactcgggggtcttccgtcca
gagatgctgctgcccatggggcttcccgagaacgtgtcggtcattgcctggggcctctcc
ctggagcgcccaacgatgatcaaatatggcatcaacaatatccgggagctggtgggccac
aaggtgaacctgcagatggtgtatgacagtcccctgtgccgcctggatgccgagccgagg
ccccctcccacacaggaggctgcgtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (16)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (25)   
   RefSeq(nuc) (1)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (10)   
   Pfam (10)   
All databases (58)   

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