KEGG   Homo sapiens (human): 2203Help
Entry
2203              CDS       T01001                                 

Gene name
FBP1, FBP
Definition
(RefSeq) fructose-bisphosphatase 1
  KO
K03841  fructose-1,6-bisphosphatase I [EC:3.1.3.11]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00030  Pentose phosphate pathway
hsa00051  Fructose and mannose metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa04152  AMPK signaling pathway
hsa04910  Insulin signaling pathway
hsa04922  Glucagon signaling pathway
Module
hsa_M00003  Gluconeogenesis, oxaloacetate => fructose-6P
Disease
H00114  Fructose-1,6-bisphosphatase deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    2203 (FBP1)
   00030 Pentose phosphate pathway
    2203 (FBP1)
   00051 Fructose and mannose metabolism
    2203 (FBP1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    2203 (FBP1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    2203 (FBP1)
   04922 Glucagon signaling pathway
    2203 (FBP1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2203 (FBP1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.11  fructose-bisphosphatase
     2203 (FBP1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2203 (FBP1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: FBPase Inositol_P
Motif
Other DBs
NCBI-GeneID: 2203
NCBI-ProteinID: NP_000498
OMIM: 611570
HGNC: 3606
Ensembl: ENSG00000165140
Vega: OTTHUMG00000020268
Pharos: P09467(Tchem)
UniProt: P09467
Structure
PDB: 

Position
9q22.32
AA seq 338 aa AA seqDB search
MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGI
AGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDP
LDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDC
GVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGK
EAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHSAQ
NT seq 1017 nt NT seq  +upstreamnt  +downstreamnt
atggctgaccaggcgcccttcgacacggacgtcaacaccctgacccgcttcgtcatggag
gagggcaggaaggcccgcggcacgggcgagttgacccagctgctcaactcgctctgcaca
gcagtcaaagccatctcttcggcggtgcgcaaggcgggcatcgcgcacctctatggcatt
gctggttctaccaacgtgacaggtgatcaagttaagaagctggacgtcctctccaacgac
ctggttatgaacatgttaaagtcatcctttgccacgtgtgttctcgtgtcagaagaagat
aaacacgccatcatagtggaaccggagaaaaggggtaaatatgtggtctgttttgatccc
cttgatggatcttccaacatcgattgccttgtgtccgttggaaccatttttggcatctat
agaaagaaatcaactgatgagccttctgagaaggatgctctgcaaccaggccggaacctg
gtggcagccggctacgcactgtatggcagtgccaccatgctggtccttgccatggactgt
ggggtcaactgcttcatgctggacccggccatcggggagttcattttggtggacaaggat
gtgaagataaaaaagaaaggtaaaatctacagccttaacgagggctacgccagggacttt
gaccctgccgtcactgagtacatccagaggaagaagttccccccagataattcagctcct
tatggggcccggtatgtgggctccatggtggctgatgttcatcgcactctggtctacgga
gggatatttctgtaccccgctaacaagaagagccccaatggaaagctgagactgctgtac
gaatgcaaccccatggcctacgtcatggagaaggctgggggaatggccaccactgggaag
gaggccgtgttagacgtcattcccacagacattcaccagagggcgccggtgatcttggga
tcccccgacgacgtgctcgagttcctgaaggtgtatgagaagcactctgcccagtga

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