KEGG   Homo sapiens (human): 2213
Entry
2213              CDS       T01001                                 
Symbol
FCGR2B, CD32, CD32B, FCG2, FCGR2, FCGR2C, FcGRIIB, FcRII-c, FcgammaRIIb, IGFR2
Name
(RefSeq) Fc gamma receptor IIb
  KO
K12560  low affinity immunoglobulin gamma Fc receptor II-b
Organism
hsa  Homo sapiens (human)
Pathway
hsa03265  Virion - Ebolavirus, Lyssavirus and Morbillivirus
hsa04145  Phagosome
hsa04380  Osteoclast differentiation
hsa04662  B cell receptor signaling pathway
hsa04666  Fc gamma R-mediated phagocytosis
hsa05150  Staphylococcus aureus infection
hsa05152  Tuberculosis
hsa05162  Measles
Disease
H00080  Systemic lupus erythematosus
H00361  Malaria
Drug target
Valziflocept: D11339
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
    2213 (FCGR2B)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    2213 (FCGR2B)
 09150 Organismal Systems
  09151 Immune system
   04662 B cell receptor signaling pathway
    2213 (FCGR2B)
   04666 Fc gamma R-mediated phagocytosis
    2213 (FCGR2B)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    2213 (FCGR2B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    2213 (FCGR2B)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    2213 (FCGR2B)
   05152 Tuberculosis
    2213 (FCGR2B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2213 (FCGR2B)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    2213 (FCGR2B)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   Fc receptors
    2213 (FCGR2B)
CD molecules [BR:hsa04090]
 Proteins
  2213 (FCGR2B)
SSDB
Motif
Pfam: Ig_2 Ig_3 ig Ig_4 I-set V-set Ig_5 Big_7 V-set_CD47 KIAA1549 ECSCR Protocadherin Adeno_E3_CR2
Other DBs
NCBI-GeneID: 2213
NCBI-ProteinID: NP_003992
OMIM: 604590
HGNC: 3618
Ensembl: ENSG00000072694
UniProt: P31994
Structure
Position
1:161647243..161678654
AA seq 310 aa
MGILSFLPVLATESDWADCKSPQPWGHMLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWIN
VLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSL
SDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPN
FSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIVAA
VVALIYCRKKRISALPGYPECREMGETLPEKPANPTNPDEADKVGAENTITYSLLMHPDA
LEEPDDQNRI
NT seq 933 nt   +upstreamnt  +downstreamnt
atgggaatcctgtcattcttacctgtccttgccactgagagtgactgggctgactgcaag
tccccccagccttggggtcatatgcttctgtggacagctgtgctattcctggctcctgtt
gctgggacacctgcagctcccccaaaggctgtgctgaaactcgagccccagtggatcaac
gtgctccaggaggactctgtgactctgacatgccgggggactcacagccctgagagcgac
tccattcagtggttccacaatgggaatctcattcccacccacacgcagcccagctacagg
ttcaaggccaacaacaatgacagcggggagtacacgtgccagactggccagaccagcctc
agcgaccctgtgcatctgactgtgctttctgagtggctggtgctccagacccctcacctg
gagttccaggagggagaaaccatcgtgctgaggtgccacagctggaaggacaagcctctg
gtcaaggtcacattcttccagaatggaaaatccaagaaattttcccgttcggatcccaac
ttctccatcccacaagcaaaccacagtcacagtggtgattaccactgcacaggaaacata
ggctacacgctgtactcatccaagcctgtgaccatcactgtccaagctcccagctcttca
ccgatggggatcattgtggctgtggtcactgggattgctgtagcggccattgttgctgct
gtagtggccttgatctactgcaggaaaaagcggatttcagctctcccaggataccctgag
tgcagggaaatgggagagaccctccctgagaaaccagccaatcccactaatcctgatgag
gctgacaaagttggggctgagaacacaatcacctattcacttctcatgcacccggatgct
ctggaagagcctgatgaccagaaccgtatttag

  All links  
Disease (3)   
   OMIM (3)   
Gene (10)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (96)   
   RefSeq(nuc) (16)   
   GenBank (40)   
   EMBL (40)   
3D Structure (3)   
   PDB (3)   
Protein domain (13)   
   Pfam (13)   
All databases (142)   

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