KEGG   Homo sapiens (human): 2217
Entry
2217              CDS       T01001                                 
Symbol
FCGRT, FCRN, FcgammaRn, alpha-chain
Name
(RefSeq) Fc gamma receptor and transporter
  KO
K24019  IgG receptor FcRn large subunit p51
Organism
hsa  Homo sapiens (human)
Drug target
Batoclimab: D11983
Efgartigimod alfa: D11876<JP/US>
Nipocalimab: D11666
Orilanolimab: D12144
Rozanolixizumab: D12182
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2217 (FCGRT)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   Fc receptors
    2217 (FCGRT)
SSDB
Motif
Pfam: MHC_I C1-set MHC_I_3
Other DBs
NCBI-GeneID: 2217
NCBI-ProteinID: NP_001129491
OMIM: 601437
HGNC: 3621
Ensembl: ENSG00000104870
Pharos: P55899(Tchem)
UniProt: P55899 A0A024QZI2
Structure
Position
19:49512661..49526428
AA seq 365 aa
MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
IPATA
NT seq 1098 nt   +upstreamnt  +downstreamnt
atgggggtcccgcggcctcagccctgggcgctggggctcctgctctttctccttcctggg
agcctgggcgcagaaagccacctctccctcctgtaccaccttaccgcggtgtcctcgcct
gccccggggactcctgccttctgggtgtccggctggctgggcccgcagcagtacctgagc
tacaatagcctgcggggcgaggcggagccctgtggagcttgggtctgggaaaaccaggtg
tcctggtattgggagaaagagaccacagatctgaggatcaaggagaagctctttctggaa
gctttcaaagctttggggggaaaaggtccctacactctgcagggcctgctgggctgtgaa
ctgggccctgacaacacctcggtgcccaccgccaagttcgccctgaacggcgaggagttc
atgaatttcgacctcaagcagggcacctggggtggggactggcccgaggccctggctatc
agtcagcggtggcagcagcaggacaaggcggccaacaaggagctcaccttcctgctattc
tcctgcccgcaccgcctgcgggagcacctggagaggggccgcggaaacctggagtggaag
gagcccccctccatgcgcctgaaggcccgacccagcagccctggcttttccgtgcttacc
tgcagcgccttctccttctaccctccggagctgcaacttcggttcctgcggaatgggctg
gccgctggcaccggccagggtgacttcggccccaacagtgacggatccttccacgcctcg
tcgtcactaacagtcaaaagtggcgatgagcaccactactgctgcattgtgcagcacgcg
gggctggcgcagcccctcagggtggagctggaatctccagccaagtcctccgtgctcgtg
gtgggaatcgtcatcggtgtcttgctactcacggcagcggctgtaggaggagctctgttg
tggagaaggatgaggagtgggctgccagccccttggatctcccttcgtggagacgacacc
ggggtcctcctgcccaccccaggggaggcccaggatgctgatttgaaggatgtaaatgtg
attccagccaccgcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Drug (5)   
   KEGG DRUG (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (41)   
   RefSeq(nuc) (7)   
   GenBank (17)   
   EMBL (17)   
3D Structure (23)   
   PDB (23)   
Protein domain (3)   
   Pfam (3)   
All databases (99)   

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