KEGG   Homo sapiens (human): 2241
Entry
2241              CDS       T01001                                 
Symbol
FER, PPP1R74, TYK3, p94-Fer
Name
(RefSeq) FER tyrosine kinase
  KO
K08889  tyrosine-protein kinase Fer [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04520  Adherens junction
Network
nt06541  Cytoskeleton in neurons
  Element
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    2241 (FER)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2241 (FER)
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    2241 (FER)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2241 (FER)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     2241 (FER)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  FES family
   2241 (FER)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     2241 (FER)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Bin/Amphiphysin/Rvs (BAR) family proteins
   F-BAR proteins
    2241 (FER)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 FCH ABC1 PGDH_inter
Other DBs
NCBI-GeneID: 2241
NCBI-ProteinID: NP_005237
OMIM: 176942
HGNC: 3655
Ensembl: ENSG00000151422
UniProt: P16591 W0S0X4
Structure
Position
5:108747897..109196841
AA seq 822 aa
MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
NT seq 2469 nt   +upstreamnt  +downstreamnt
atggggtttgggagtgacctgaagaattcacatgaagcagtgttaaaattgcaagactgg
gaattacggttactggaaacagtaaagaaatttatggccctgagaataaaaagtgataaa
gaatatgcatctactttacagaacctttgtaatcaagttgataaggaaagtactgtccaa
atgaattatgtcagcaacgtatccaagtcttggctacttatgattcagcagacagaacaa
cttagtaggataatgaagacacatgcagaggacttgaactctggacctttacacaggctc
accatgatgattaaggacaagcagcaggtgaagaaaagttacataggtgttcatcagcag
atagaggcagagatgatcaaggttaccaaaacagaattggagaagttaaaatgcagctat
agacaattaataaaagaaatgaattctgccaaagagaaatataaagaagctttagctaaa
gggaaggaaactgaaaaggccaaggaacgatacgacaaagccacaatgaaacttcatatg
ttgcacaatcagtatgtattggcgttgaaaggggcacagctccatcagaatcagtattat
gatatcacacttcccctgcttctggactccttacaaaagatgcaagaagaaatgataaaa
gcactcaaaggtatatttgatgaatacagccagataaccagtcttgtcacagaggaaata
gtgaatgtccataaagagattcaaatgtcggttgaacagatagatcctagtacagaatac
aataatttcatagatgttcacagaacaacggctgctaaagaacaagaaatagagtttgat
acttccttactggaagaaaatgaaaatcttcaggcaaatgagatcatgtggaataactta
acagcagaaagtttgcaagtaatgttgaaaacgttagcggaagaacttatgcaaacacag
cagatgcttttaaacaaggaggaggctgttttggagttagagaagagaattgaagaatct
tctgaaacttgtgagaagaagtctgatattgtgcttctgctaagccaaaaacaggcactt
gaagaactgaaacagtcagtccagcagctgagatgcactgaagcaaagttttcagcacag
aaggaattactagagcaaaaagtgcaagaaaatgatgggaaagagccacctccagtagta
aattatgaagaagatgcacgatcagttacatctatggaaagaaaggagaggctatccaaa
tttgaatctattcgtcattcaattgctggaataattaggtctccaaaatctgcactgggc
tcttcagcactttctgatatgatctccatcagtgagaagcctttggcagaacaggactgg
taccatggtgcaattcccagaatagaagctcaagaactgttaaaaaaacaaggagacttt
ttggtgcgagagagtcatgggaaacctggtgaatatgtcctttctgtatattctgatgga
cagaggagacattttatcatacaatatgttgataacatgtatcgattcgagggcactggg
ttttcaaacattcctcaacttatagatcatcactatacaacaaaacaggtcatcactaag
aaatcaggtgtagttctgctgaatcctattcctaaggacaagaaatggattctcagtcat
gaagatgtcatattgggagaattactgggcaagggaaattttggtgaagtatataagggc
acattaaaggataaaacttctgttgctgttaaaacatgtaaagaagatcttcctcaggaa
ttgaaaataaaatttttacaagaagccaaaattctcaagcaatatgatcatcccaatatt
gtcaaacttataggagtttgcacacaaagacagcctgtctacatcattatggaactggtt
tcaggaggtgatttcctcacctttctgagaaggaagaaggatgaactaaaactcaaacag
ttagtgaaattttcattagacgctgctgctggtatgttgtatctcgagagtaaaaactgt
atacacagggaccttgctgcaagaaactgcctggtaggtgaaaataatgttctgaaaatc
agtgactttggaatgtctcgtcaagaggatggtggagtgtattcatcttctggcttaaag
cagattcccattaaatggacagcaccggaagctcttaattatgggagatacagttcagag
agtgacgtgtggagctttggcatccttctctgggagaccttcagcttaggggtttgtccg
taccctggaatgacaaatcagcaagcaagagagcaagtagaaagaggataccggatgtca
gctccccagcactgtccagaggatatttccaaaatcatgatgaagtgttgggattataaa
cctgaaaatcgccctaagttcagtgaacttcagaaagagctcactatcatcaagagaaaa
ctcacatag

  All links  
Disease (1)   
   OMIM (1)   
Gene (7)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (44)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (41)   
DNA sequence (78)   
   RefSeq(nuc) (48)   
   GenBank (15)   
   EMBL (15)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (138)   

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