KEGG   Homo sapiens (human): 2242
Entry
2242              CDS       T01001                                 
Symbol
FES, FPS
Name
(RefSeq) FES proto-oncogene, tyrosine kinase
  KO
K07527  tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Network
nt06541  Cytoskeleton in neurons
  Element
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2242 (FES)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2242 (FES)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2242 (FES)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     2242 (FES)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  FES family
   2242 (FES)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Bin/Amphiphysin/Rvs (BAR) family proteins
   F-BAR proteins
    2242 (FES)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 FCH ABC1 DUF7063 SnoaL_5
Other DBs
NCBI-GeneID: 2242
NCBI-ProteinID: NP_001996
OMIM: 190030
HGNC: 3657
Ensembl: ENSG00000182511
UniProt: P07332
Structure
Position
15:90884504..90895776
AA seq 822 aa
MGFSSELCSPQGHGVLQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMSLQDSGGQS
RAISPDSPISQSWAEITSQTEGLSRLLRQHAEDLNSGPLSKLSLLIRERQQLRKTYSEQW
QQLQQELTKTHSQDIEKLKSQYRALARDSAQAKRKYQEASKDKDRDKAKDKYVRSLWKLF
AHHNRYVLGVRAAQLHHQHHHQLLLPGLLRSLQDLHEEMACILKEILQEYLEISSLVQDE
VVAIHREMAAAAARIQPEAEYQGFLRQYGSAPDVPPCVTFDESLLEEGEPLEPGELQLNE
LTVESVQHTLTSVTDELAVATEMVFRRQEMVTQLQQELRNEEENTHPRERVQLLGKRQVL
QEALQGLQVALCSQAKLQAQQELLQTKLEHLGPGEPPPVLLLQDDRHSTSSSEQEREGGR
TPTLEILKSHISGIFRPKFSLPPPLQLIPEVQKPLHEQLWYHGAIPRAEVAELLVHSGDF
LVRESQGKQEYVLSVLWDGLPRHFIIQSLDNLYRLEGEGFPSIPLLIDHLLSTQQPLTKK
SGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDL
KAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTL
LQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLR
QVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLP
CPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKRHR
NT seq 2469 nt   +upstreamnt  +downstreamnt
atgggcttctcttccgagctgtgcagcccccagggccacggggtcctgcagcaaatgcag
gaggccgagcttcgtctactggagggcatgagaaagtggatggcccagcgggtcaagagt
gacagggagtatgcaggactgcttcaccacatgtccctgcaggacagtgggggccagagc
cgggccatcagccctgacagccccatcagtcagtcctgggctgagatcaccagccaaact
gagggcctgagccgcttgctgcggcagcacgcagaggatctgaactcagggcccctgagc
aagctgagcctgctcatccgggaacggcagcagcttcgcaagacctacagcgagcagtgg
cagcagctgcagcaggagctcaccaagacccacagccaggacattgagaagctgaagagc
cagtaccgagctctggcacgggacagtgcccaagccaagcgcaagtaccaggaggccagc
aaagacaaggaccgtgacaaggctaaggacaagtatgtgcgcagcctgtggaagctcttt
gctcaccacaaccgctatgtgctgggcgtgcgggctgcgcagctacaccaccagcaccac
caccagctcctgctgcccggcctgctgcggtcactgcaggacctgcacgaggagatggct
tgcatcctgaaggagatcctgcaggaatacctggagattagcagcctggtgcaggatgag
gtggtggccattcaccgggagatggctgcagctgctgcccgcatccagcctgaggctgag
taccaaggcttcctgcgacagtatgggtccgcacctgacgtcccaccctgtgtcacgttc
gatgagtcactgcttgaggagggtgaaccgctggagcctggggagctccagctgaacgag
ctgactgtggagagcgtgcagcacacgctgacctcagtgacagatgagctggctgtggcc
accgagatggtgttcaggcggcaggagatggttacgcagctgcaacaggagctccggaat
gaagaggagaacacccacccccgggagcgggtgcagctgctgggcaagaggcaagtgctg
caagaagcactgcaggggctgcaggtagcgctgtgcagccaggccaagctgcaggcccag
caggagttgctgcagaccaagctggagcacctgggccccggcgagcccccgcctgtgctg
ctcctgcaggatgaccgccactccacgtcgtcctcggagcaggagcgagaggggggaagg
acacccacgctggagatccttaagagccacatctcaggaatcttccgccccaagttctcg
ctccctccaccgctgcagctcattccggaggtgcagaagcccctgcatgagcagctgtgg
taccacggggccatcccgagggcagaggtggctgagctgctggtgcactctggggacttc
ctggtgcgggagagccagggcaagcaggagtacgtgctgtcggtgctgtgggatggtctg
ccccggcacttcatcatccagtccttggataacctgtaccgactggaaggggaaggcttt
cctagcattcctttgctcatcgaccacctactgagcacccagcagcccctcaccaagaag
agtggtgttgtcctgcacagggctgtgcccaaggacaagtgggtgctgaaccatgaggac
ctggtgttgggtgagcagattggacgggggaactttggcgaagtgttcagcggacgcctg
cgagccgacaacaccctggtggcggtgaagtcttgtcgagagacgctcccacctgacctc
aaggccaagtttctacaggaagcgaggatcctgaagcagtacagccaccccaacatcgtg
cgtctcattggtgtctgcacccagaagcagcccatctacatcgtcatggagcttgtgcag
gggggcgacttcctgaccttcctccgcacggagggggcccgcctgcgggtgaagactctg
ctgcagatggtgggggatgcagctgctggcatggagtacctggagagcaagtgctgcatc
caccgggacctggctgctcggaactgcctggtgacagagaagaatgtcctgaagatcagt
gactttgggatgtcccgagaggaagccgatggggtctatgcagcctcagggggcctcaga
caagtccccgtgaagtggaccgcacctgaggcccttaactacggccgctactcctccgaa
agcgacgtgtggagctttggcatcttgctctgggagaccttcagcctgggggcctccccc
tatcccaacctcagcaatcagcagacacgggagtttgtggagaaggggggccgtctgccc
tgcccagagctgtgtcctgatgccgtgttcaggctcatggagcagtgctgggcctatgag
cctgggcagcggcccagcttcagcaccatctaccaggagctgcagagcatccgaaagcgg
catcggtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (11)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (36)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (34)   
DNA sequence (60)   
   RefSeq(nuc) (34)   
   GenBank (13)   
   EMBL (13)   
3D Structure (12)   
   PDB (12)   
Protein domain (7)   
   Pfam (7)   
All databases (127)   

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