KEGG   Homo sapiens (human): 2242
Entry
2242              CDS       T01001                                 

Symbol
FES, FPS
Name
(RefSeq) FES proto-oncogene, tyrosine kinase
  KO
K07527  tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2242 (FES)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2242 (FES)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2242 (FES)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     2242 (FES)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  FES family
   2242 (FES)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Bin/Amphiphysin/Rvs (BAR) family proteins
   F-BAR proteins
    2242 (FES)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 FCH Muted
Other DBs
NCBI-GeneID: 2242
NCBI-ProteinID: NP_001996
OMIM: 190030
HGNC: 3657
Ensembl: ENSG00000182511
Vega: OTTHUMG00000044456
Pharos: P07332(Tchem)
UniProt: P07332 A0A024RC92
Structure
PDB: 

Position
15q26.1
AA seq 822 aa
MGFSSELCSPQGHGVLQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMSLQDSGGQS
RAISPDSPISQSWAEITSQTEGLSRLLRQHAEDLNSGPLSKLSLLIRERQQLRKTYSEQW
QQLQQELTKTHSQDIEKLKSQYRALARDSAQAKRKYQEASKDKDRDKAKDKYVRSLWKLF
AHHNRYVLGVRAAQLHHQHHHQLLLPGLLRSLQDLHEEMACILKEILQEYLEISSLVQDE
VVAIHREMAAAAARIQPEAEYQGFLRQYGSAPDVPPCVTFDESLLEEGEPLEPGELQLNE
LTVESVQHTLTSVTDELAVATEMVFRRQEMVTQLQQELRNEEENTHPRERVQLLGKRQVL
QEALQGLQVALCSQAKLQAQQELLQTKLEHLGPGEPPPVLLLQDDRHSTSSSEQEREGGR
TPTLEILKSHISGIFRPKFSLPPPLQLIPEVQKPLHEQLWYHGAIPRAEVAELLVHSGDF
LVRESQGKQEYVLSVLWDGLPRHFIIQSLDNLYRLEGEGFPSIPLLIDHLLSTQQPLTKK
SGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDL
KAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTL
LQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLR
QVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLP
CPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKRHR
NT seq 2469 nt   +upstreamnt  +downstreamnt
atgggcttctcttccgagctgtgcagcccccagggccacggggtcctgcagcaaatgcag
gaggccgagcttcgtctactggagggcatgagaaagtggatggcccagcgggtcaagagt
gacagggagtatgcaggactgcttcaccacatgtccctgcaggacagtgggggccagagc
cgggccatcagccctgacagccccatcagtcagtcctgggctgagatcaccagccaaact
gagggcctgagccgcttgctgcggcagcacgcagaggatctgaactcagggcccctgagc
aagctgagcctgctcatccgggaacggcagcagcttcgcaagacctacagcgagcagtgg
cagcagctgcagcaggagctcaccaagacccacagccaggacattgagaagctgaagagc
cagtaccgagctctggcacgggacagtgcccaagccaagcgcaagtaccaggaggccagc
aaagacaaggaccgtgacaaggctaaggacaagtatgtgcgcagcctgtggaagctcttt
gctcaccacaaccgctatgtgctgggcgtgcgggctgcgcagctacaccaccagcaccac
caccagctcctgctgcccggcctgctgcggtcactgcaggacctgcacgaggagatggct
tgcatcctgaaggagatcctgcaggaatacctggagattagcagcctggtgcaggatgag
gtggtggccattcaccgggagatggctgcagctgctgcccgcatccagcctgaggctgag
taccaaggcttcctgcgacagtatgggtccgcacctgacgtcccaccctgtgtcacgttc
gatgagtcactgcttgaggagggtgaaccgctggagcctggggagctccagctgaacgag
ctgactgtggagagcgtgcagcacacgctgacctcagtgacagatgagctggctgtggcc
accgagatggtgttcaggcggcaggagatggttacgcagctgcaacaggagctccggaat
gaagaggagaacacccacccccgggagcgggtgcagctgctgggcaagaggcaagtgctg
caagaagcactgcaggggctgcaggtagcgctgtgcagccaggccaagctgcaggcccag
caggagttgctgcagaccaagctggagcacctgggccccggcgagcccccgcctgtgctg
ctcctgcaggatgaccgccactccacgtcgtcctcggagcaggagcgagaggggggaagg
acacccacgctggagatccttaagagccacatctcaggaatcttccgccccaagttctcg
ctccctccaccgctgcagctcattccggaggtgcagaagcccctgcatgagcagctgtgg
taccacggggccatcccgagggcagaggtggctgagctgctggtgcactctggggacttc
ctggtgcgggagagccagggcaagcaggagtacgtgctgtcggtgctgtgggatggtctg
ccccggcacttcatcatccagtccttggataacctgtaccgactggaaggggaaggcttt
cctagcattcctttgctcatcgaccacctactgagcacccagcagcccctcaccaagaag
agtggtgttgtcctgcacagggctgtgcccaaggacaagtgggtgctgaaccatgaggac
ctggtgttgggtgagcagattggacgggggaactttggcgaagtgttcagcggacgcctg
cgagccgacaacaccctggtggcggtgaagtcttgtcgagagacgctcccacctgacctc
aaggccaagtttctacaggaagcgaggatcctgaagcagtacagccaccccaacatcgtg
cgtctcattggtgtctgcacccagaagcagcccatctacatcgtcatggagcttgtgcag
gggggcgacttcctgaccttcctccgcacggagggggcccgcctgcgggtgaagactctg
ctgcagatggtgggggatgcagctgctggcatggagtacctggagagcaagtgctgcatc
caccgggacctggctgctcggaactgcctggtgacagagaagaatgtcctgaagatcagt
gactttgggatgtcccgagaggaagccgatggggtctatgcagcctcagggggcctcaga
caagtccccgtgaagtggaccgcacctgaggcccttaactacggccgctactcctccgaa
agcgacgtgtggagctttggcatcttgctctgggagaccttcagcctgggggcctccccc
tatcccaacctcagcaatcagcagacacgggagtttgtggagaaggggggccgtctgccc
tgcccagagctgtgtcctgatgccgtgttcaggctcatggagcagtgctgggcctatgag
cctgggcagcggcccagcttcagcaccatctaccaggagctgcagagcatccgaaagcgg
catcggtga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (15)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (42)   
   RefSeq(nuc) (16)   
   GenBank (13)   
   EMBL (13)   
Protein domain (5)   
   Pfam (5)   
All databases (84)   

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