KEGG   Homo sapiens (human): 2244
Entry
2244              CDS       T01001                                 
Symbol
FGB, HEL-S-78p
Name
(RefSeq) fibrinogen beta chain
  KO
K03904  fibrinogen beta chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
hsa04611  Platelet activation
hsa04613  Neutrophil extracellular trap formation
hsa05171  Coronavirus disease - COVID-19
Network
nt06171  SARS coronavirus 2 (SARS-CoV-2)
nt06514  Coagulation cascade
  Element
N01502  Lectin pathway of coagulation cascade, fibrinogen to fibrin
N01513  Common pathway of coagulation cascade, fibrinogen to fibrin
Disease
H00222  Congenital fibrinogen deficiency
H00223  Inherited thrombophilia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    2244 (FGB)
   04611 Platelet activation
    2244 (FGB)
   04613 Neutrophil extracellular trap formation
    2244 (FGB)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    2244 (FGB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2244 (FGB)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    2244 (FGB)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   2244 (FGB)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Extracellular matrix molecules
   2244 (FGB)
 Hyaluronan
  Extracellular matrix or blood plasma proteins
   2244 (FGB)
SSDB
Motif
Pfam: Fibrinogen_C Fib_alpha CALCOCO1 MitMem_reg SF-assemblin
Other DBs
NCBI-GeneID: 2244
NCBI-ProteinID: NP_005132
OMIM: 134830
HGNC: 3662
Ensembl: ENSG00000171564
CPD: C00290 C02404
UniProt: P02675 V9HVY1
Structure
Position
4:154562980..154572807
AA seq 491 aa
MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR
PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE
RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE
CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK
QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT
VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP
RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
SMKIRPFFPQQ
NT seq 1476 nt   +upstreamnt  +downstreamnt
atgaaaaggatggtttcttggagcttccacaaacttaaaaccatgaaacatctattattg
ctactattgtgtgtttttctagttaagtcccaaggtgtcaacgacaatgaggagggtttc
ttcagtgcccgtggtcatcgaccccttgacaagaagagagaagaggctcccagcctgagg
cctgccccaccgcccatcagtggaggtggctatcgggctcgtccagccaaagcagctgcc
actcaaaagaaagtagaaagaaaagcccctgatgctggaggctgtcttcacgctgaccca
gacctgggggtgttgtgtcctacaggatgtcagttgcaagaggctttgctacaacaggaa
aggccaatcagaaatagtgttgatgagttaaataacaatgtggaagctgtttcccagacc
tcctcttcttcctttcagtacatgtatttgctgaaagacctgtggcaaaagaggcagaag
caagtaaaagataatgaaaatgtagtcaatgagtactcctcagaactggaaaagcaccaa
ttatatatagatgagactgtgaatagcaatatcccaactaaccttcgtgtgcttcgttca
atcctggaaaacctgagaagcaaaatacaaaagttagaatctgatgtctcagctcaaatg
gaatattgtcgcaccccatgcactgtcagttgcaatattcctgtggtgtctggcaaagaa
tgtgaggaaattatcaggaaaggaggtgaaacatctgaaatgtatctcattcaacctgac
agttctgtcaaaccgtatagagtatactgtgacatgaatacagaaaatggaggatggaca
gtgattcagaaccgtcaagacggtagtgttgactttggcaggaaatgggatccatataaa
cagggatttggaaatgttgcaaccaacacagatgggaagaattactgtggcctaccaggt
gaatattggcttggaaatgataaaattagccagcttaccaggatgggacccacagaactt
ttgatagaaatggaggactggaaaggagacaaagtaaaggctcactatggaggattcact
gtacagaatgaagccaacaaataccagatctcagtgaacaaatacagaggaacagccggt
aatgccctcatggatggagcatctcagctgatgggagaaaacaggaccatgaccattcac
aacggcatgttcttcagcacgtatgacagagacaatgacggctggttaacatcagatccc
agaaaacagtgttctaaagaagacggtggtggatggtggtataatagatgtcatgcagcc
aatccaaacggcagatactactggggtggacagtacacctgggacatggcaaagcatggc
acagatgatggtgtagtatggatgaattggaaggggtcatggtactcaatgaggaagatg
agtatgaagatcaggcccttcttcccacagcaatag

  All links  
Disease (3)   
   OMIM (3)   
Gene (12)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (12)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (41)   
   RefSeq(nuc) (9)   
   GenBank (16)   
   EMBL (16)   
3D Structure (40)   
   PDB (40)   
Protein domain (5)   
   Pfam (5)   
All databases (113)   

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