| Entry |
|
|---|
| Gene name |
FGG
|
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| Definition |
(RefSeq) fibrinogen gamma chain
|
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| KO |
|
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| Organism |
|
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| Pathway |
| hsa04610 | Complement and coagulation cascades |
| hsa04613 | Neutrophil extracellular trap formation |
| hsa05150 | Staphylococcus aureus infection |
|
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| Network |
nt06136 Complement activation (viruses) nt06171 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
|---|
| Element |
| N01315 | Lectin pathway of coagulation activation |
| N01316 | SARS-CoV-2 S/N to lectin pathway of coagulation activation |
|
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| Disease |
| H00223 | Inherited thrombophilia |
|
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
2266 (FGG)
04611 Platelet activation
2266 (FGG)
04613 Neutrophil extracellular trap formation
2266 (FGG)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
2266 (FGG)
09171 Infectious disease: bacterial
05150 Staphylococcus aureus infection
2266 (FGG)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
2266 (FGG)
00536 Glycosaminoglycan binding proteins [BR:hsa00536]
2266 (FGG)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
2266 (FGG)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Heparin
Extracellular matrix molecules
2266 (FGG)
Hyaluronan
Extracellular matrix or blood plasma proteins
2266 (FGG)
|
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| SSDB |
|
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| Motif |
|
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| Other DBs |
|
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| Structure |
PDB: |
|---|
| Position |
4q32.1
|
|---|
| AA seq |
453 aa
MSWSLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQT
KVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIM
KYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQ
DIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEG
FGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKY
RLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGW
WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
GEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL |
|---|
| NT seq |
1362 nt +upstreamnt +downstreamnt
atgagttggtccttgcacccccggaatttaattctctacttctatgctcttttatttctc
tcttcaacatgtgtagcatatgttgctaccagagacaactgctgcatcttagatgaaaga
ttcggtagttattgtccaactacctgtggcattgcagatttcctgtctacttatcaaacc
aaagtagacaaggatctacagtctttggaagacatcttacatcaagttgaaaacaaaaca
tcagaagtcaaacagctgataaaagcaatccaactcacttataatcctgatgaatcatca
aaaccaaatatgatagacgctgctactttgaagtccaggaaaatgttagaagaaattatg
aaatatgaagcatcgattttaacacatgactcaagtattcgatatttgcaggaaatatat
aattcaaataatcaaaagattgttaacctgaaagagaaggtagcccagcttgaagcacag
tgccaggaaccttgcaaagacacggtgcaaatccatgatatcactgggaaagattgtcaa
gacattgccaataagggagctaaacagagcgggctttactttattaaacctctgaaagct
aaccagcaattcttagtctactgtgaaatcgatgggtctggaaatggatggactgtgttt
cagaagagacttgatggcagtgtagatttcaagaaaaactggattcaatataaagaagga
tttggacatctgtctcctactggcacaacagaattttggctgggaaatgagaagattcat
ttgataagcacacagtctgccatcccatatgcattaagagtggaactggaagactggaat
ggcagaaccagtactgcagactatgccatgttcaaggtgggacctgaagctgacaagtac
cgcctaacatatgcctacttcgctggtggggatgctggagatgcctttgatggctttgat
tttggcgatgatcctagtgacaagtttttcacatcccataatggcatgcagttcagtacc
tgggacaatgacaatgataagtttgaaggcaactgtgctgaacaggatggatctggttgg
tggatgaacaagtgtcacgctggccatctcaatggagtttattaccaaggtggcacttac
tcaaaagcatctactcctaatggttatgataatggcattatttgggccacttggaaaacc
cggtggtattccatgaagaaaaccactatgaagataatcccattcaacagactcacaatt
ggagaaggacagcaacaccacctggggggagccaaacaggtcagaccagagcaccctgcg
gaaacagaatatgactcactttaccctgaggatgatttgtag |
|---|
