KEGG   Homo sapiens (human): 2272Help
Entry
2272              CDS       T01001                                 

Gene name
FHIT, AP3Aase, FRA3B
Definition
(RefSeq) fragile histidine triad
  KO
K01522  bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa05222  Small cell lung cancer
hsa05223  Non-small cell lung cancer
Disease
H00013  Small cell lung cancer
H00014  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    2272 (FHIT)
 09160 Human Diseases
  09162 Cancers: Specific types
   05222 Small cell lung cancer
    2272 (FHIT)
   05223 Non-small cell lung cancer
    2272 (FHIT)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.29  bis(5'-adenosyl)-triphosphatase
     2272 (FHIT)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: HIT DcpS_C
Motif
Other DBs
NCBI-GeneID: 2272
NCBI-ProteinID: NP_001159715
OMIM: 601153
HGNC: 3701
Ensembl: ENSG00000189283
Vega: OTTHUMG00000158591
Pharos: P49789(Tchem)
UniProt: P49789 A0A024R366
Structure
PDB: 

Position
3p14.2
AA seq 147 aa AA seqDB search
MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQ
TTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKH
DKEDFPASWRSEEEMAAEAAALRVYFQ
NT seq 444 nt NT seq  +upstreamnt  +downstreamnt
atgtcgttcagatttggccaacatctcatcaagccctctgtagtgtttctcaaaacagaa
ctgtccttcgctcttgtgaataggaaacctgtggtaccaggacatgtccttgtgtgcccg
ctgcggccagtggagcgcttccatgacctgcgtcctgatgaagtggccgatttgtttcag
acgacccagagagtcgggacagtggtggaaaaacatttccatgggacctctctcaccttt
tccatgcaggatggccccgaagccggacagactgtgaagcacgttcacgtccatgttctt
cccaggaaggctggagactttcacaggaatgacagcatctatgaggagctccagaaacat
gacaaggaggactttcctgcctcttggagatcagaggaggaaatggcagcagaagccgca
gctctgcgggtctactttcagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (2)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (17)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (39)   
   RefSeq(nuc) (17)   
   GenBank (11)   
   EMBL (11)   
Protein domain (2)   
   Pfam (2)   
All databases (85)   

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