KEGG   Homo sapiens (human): 22802
Entry
22802             CDS       T01001                                 
Symbol
CLCA4, CaCC, CaCC2
Name
(RefSeq) chloride channel accessory 4
  KO
K05030  calcium-activated chloride channel regulator 3/4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04924  Renin secretion
hsa04972  Pancreatic secretion
Drug target
Crofelemer: D03605<US>
Niflumic acid: D08275
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    22802 (CLCA4)
  09154 Digestive system
   04972 Pancreatic secretion
    22802 (CLCA4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    22802 (CLCA4)
Ion channels [BR:hsa04040]
 Chloride channels
  Chloride channel, calcium-activated (CaCC)
   22802 (CLCA4)
SSDB
Motif
Pfam: CLCA VWA VWA_2 VWA_3 GBD_IRG7_N
Other DBs
NCBI-GeneID: 22802
NCBI-ProteinID: NP_036260
OMIM: 616857
HGNC: 2018
Ensembl: ENSG00000016602
UniProt: Q14CN2
Position
1:86547078..86580754
AA seq 919 aa
MGLFRGFVFLLVLCLLHQSNTSFIKLNNNGFEDIVIVIDPSVPEDEKIIEQIEDMVTTAS
TYLFEATEKRFFFKNVSILIPENWKENPQYKRPKHENHKHADVIVAPPTLPGRDEPYTKQ
FTECGEKGEYIHFTPDLLLGKKQNEYGPPGKLFVHEWAHLRWGVFDEYNEDQPFYRAKSK
KIEATRCSAGISGRNRVYKCQGGSCLSRACRIDSTTKLYGKDCQFFPDKVQTEKASIMFM
QSIDSVVEFCNEKTHNQEAPSLQNIKCNFRSTWEVISNSEDFKNTIPMVTPPPPPVFSLL
KISQRIVCLVLDKSGSMGGKDRLNRMNQAAKHFLLQTVENGSWVGMVHFDSTATIVNKLI
QIKSSDERNTLMAGLPTYPLGGTSICSGIKYAFQVIGELHSQLDGSEVLLLTDGEDNTAS
SCIDEVKQSGAIVHFIALGRAADEAVIEMSKITGGSHFYVSDEAQNNGLIDAFGALTSGN
TDLSQKSLQLESKGLTLNSNAWMNDTVIIDSTVGKDTFFLITWNSLPPSISLWDPSGTIM
ENFTVDATSKMAYLSIPGTAKVGTWAYNLQAKANPETLTITVTSRAANSSVPPITVNAKM
NKDVNSFPSPMIVYAEILQGYVPVLGANVTAFIESQNGHTEVLELLDNGAGADSFKNDGV
YSRYFTAYTENGRYSLKVRAHGGANTARLKLRPPLNRAAYIPGWVVNGEIEANPPRPEID
EDTQTTLEDFSRTASGGAFVVSQVPSLPLPDQYPPSQITDLDATVHEDKIILTWTAPGDN
FDVGKVQRYIIRISASILDLRDSFDDALQVNTTDLSPKEANSKESFAFKPENISEENATH
IFIAIKSIDKSNLTSKVSNIAQVTLFIPQANPDDIDPTPTPTPTPTPDKSHNSGVNISTL
VLSVIGSVVIVNFILSTTI
NT seq 2760 nt   +upstreamnt  +downstreamnt
atggggttattcagaggttttgttttcctcttagttctgtgcctgctgcaccagtcaaat
acttccttcattaagctgaataataatggctttgaagatattgtcattgttatagatcct
agtgtgccagaagatgaaaaaataattgaacaaatagaggatatggtgactacagcttct
acgtacctgtttgaagccacagaaaaaagattttttttcaaaaatgtatctatattaatt
cctgagaattggaaggaaaatcctcagtacaaaaggccaaaacatgaaaaccataaacat
gctgatgttatagttgcaccacctacactcccaggtagagatgaaccatacaccaagcag
ttcacagaatgtggagagaaaggcgaatacattcacttcacccctgaccttctacttgga
aaaaaacaaaatgaatatggaccaccaggcaaactgtttgtccatgagtgggctcacctc
cggtggggagtgtttgatgagtacaatgaagatcagcctttctaccgtgctaagtcaaaa
aaaatcgaagcaacaaggtgttccgcaggtatctctggtagaaatagagtttataagtgt
caaggaggcagctgtcttagtagagcatgcagaattgattctacaacaaaactgtatgga
aaagattgtcaattctttcctgataaagtacaaacagaaaaagcatccataatgtttatg
caaagtattgattctgttgttgaattttgtaacgaaaaaacccataatcaagaagctcca
agcctacaaaacataaagtgcaattttagaagtacatgggaggtgattagcaattctgag
gattttaaaaacaccatacccatggtgacaccacctcctccacctgtcttctcattgctg
aagatcagtcaaagaattgtgtgcttagttcttgataagtctggaagcatggggggtaag
gaccgcctaaatcgaatgaatcaagcagcaaaacatttcctgctgcagactgttgaaaat
ggatcctgggtggggatggttcactttgatagtactgccactattgtaaataagctaatc
caaataaaaagcagtgatgaaagaaacacactcatggcaggattacctacatatcctctg
ggaggaacttccatctgctctggaattaaatatgcatttcaggtgattggagagctacat
tcccaactcgatggatccgaagtactgctgctgactgatggggaggataacactgcaagt
tcttgtattgatgaagtgaaacaaagtggggccattgttcattttattgctttgggaaga
gctgctgatgaagcagtaatagagatgagcaagataacaggaggaagtcatttttatgtt
tcagatgaagctcagaacaatggcctcattgatgcttttggggctcttacatcaggaaat
actgatctctcccagaagtcccttcagctcgaaagtaagggattaacactgaatagtaat
gcctggatgaacgacactgtcataattgatagtacagtgggaaaggacacgttctttctc
atcacatggaacagtctgcctcccagtatttctctctgggatcccagtggaacaataatg
gaaaatttcacagtggatgcaacttccaaaatggcctatctcagtattccaggaactgca
aaggtgggcacttgggcatacaatcttcaagccaaagcgaacccagaaacattaactatt
acagtaacttctcgagcagcaaattcttctgtgcctccaatcacagtgaatgctaaaatg
aataaggacgtaaacagtttccccagcccaatgattgtttacgcagaaattctacaagga
tatgtacctgttcttggagccaatgtgactgctttcattgaatcacagaatggacataca
gaagttttggaacttttggataatggtgcaggcgctgattctttcaagaatgatggagtc
tactccaggtattttacagcatatacagaaaatggcagatatagcttaaaagttcgggct
catggaggagcaaacactgccaggctaaaattacggcctccactgaatagagccgcgtac
ataccaggctgggtagtgaacggggaaattgaagcaaacccgccaagacctgaaattgat
gaggatactcagaccaccttggaggatttcagccgaacagcatccggaggtgcatttgtg
gtatcacaagtcccaagccttcccttgcctgaccaatacccaccaagtcaaatcacagac
cttgatgccacagttcatgaggataagattattcttacatggacagcaccaggagataat
tttgatgttggaaaagttcaacgttatatcataagaataagtgcaagtattcttgatcta
agagacagttttgatgatgctcttcaagtaaatactactgatctgtcaccaaaggaggcc
aactccaaggaaagctttgcatttaaaccagaaaatatctcagaagaaaatgcaacccac
atatttattgccattaaaagtatagataaaagcaatttgacatcaaaagtatccaacatt
gcacaagtaactttgtttatccctcaagcaaatcctgatgacattgatcctacacctact
cctactcctactcctactcctgataaaagtcataattctggagttaatatttctacgctg
gtattgtctgtgattgggtctgttgtaattgttaactttattttaagtaccaccatttga

  All links  
Disease (1)   
   OMIM (1)   
Gene (22)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (30)   
   RefSeq(nuc) (4)   
   GenBank (13)   
   EMBL (13)   
Protein domain (5)   
   Pfam (5)   
All databases (63)   

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