KEGG   Homo sapiens (human): 22802
Entry
22802             CDS       T01001                                 

Gene name
CLCA4, CaCC, CaCC2
Definition
(RefSeq) chloride channel accessory 4
  KO
K05030  calcium-activated chloride channel regulator 3/4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04924  Renin secretion
hsa04972  Pancreatic secretion
Drug target
Niflumic acid: D08275
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    22802 (CLCA4)
  09154 Digestive system
   04972 Pancreatic secretion
    22802 (CLCA4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    22802 (CLCA4)
Ion channels [BR:hsa04040]
 Chloride channels
  Chloride channel, calcium-activated (CaCC)
   22802 (CLCA4)
SSDB
Motif
Pfam: CLCA VWA VWA_2 VWA_CoxE
Other DBs
NCBI-GeneID: 22802
NCBI-ProteinID: NP_036260
OMIM: 616857
HGNC: 2018
Ensembl: ENSG00000016602
Vega: OTTHUMG00000010260
Pharos: Q14CN2(Tbio)
UniProt: Q14CN2
Position
1p22.3
AA seq 919 aa
MGLFRGFVFLLVLCLLHQSNTSFIKLNNNGFEDIVIVIDPSVPEDEKIIEQIEDMVTTAS
TYLFEATEKRFFFKNVSILIPENWKENPQYKRPKHENHKHADVIVAPPTLPGRDEPYTKQ
FTECGEKGEYIHFTPDLLLGKKQNEYGPPGKLFVHEWAHLRWGVFDEYNEDQPFYRAKSK
KIEATRCSAGISGRNRVYKCQGGSCLSRACRIDSTTKLYGKDCQFFPDKVQTEKASIMFM
QSIDSVVEFCNEKTHNQEAPSLQNIKCNFRSTWEVISNSEDFKNTIPMVTPPPPPVFSLL
KISQRIVCLVLDKSGSMGGKDRLNRMNQAAKHFLLQTVENGSWVGMVHFDSTATIVNKLI
QIKSSDERNTLMAGLPTYPLGGTSICSGIKYAFQVIGELHSQLDGSEVLLLTDGEDNTAS
SCIDEVKQSGAIVHFIALGRAADEAVIEMSKITGGSHFYVSDEAQNNGLIDAFGALTSGN
TDLSQKSLQLESKGLTLNSNAWMNDTVIIDSTVGKDTFFLITWNSLPPSISLWDPSGTIM
ENFTVDATSKMAYLSIPGTAKVGTWAYNLQAKANPETLTITVTSRAANSSVPPITVNAKM
NKDVNSFPSPMIVYAEILQGYVPVLGANVTAFIESQNGHTEVLELLDNGAGADSFKNDGV
YSRYFTAYTENGRYSLKVRAHGGANTARLKLRPPLNRAAYIPGWVVNGEIEANPPRPEID
EDTQTTLEDFSRTASGGAFVVSQVPSLPLPDQYPPSQITDLDATVHEDKIILTWTAPGDN
FDVGKVQRYIIRISASILDLRDSFDDALQVNTTDLSPKEANSKESFAFKPENISEENATH
IFIAIKSIDKSNLTSKVSNIAQVTLFIPQANPDDIDPTPTPTPTPTPDKSHNSGVNISTL
VLSVIGSVVIVNFILSTTI
NT seq 2760 nt   +upstreamnt  +downstreamnt
atggggttattcagaggttttgttttcctcttagttctgtgcctgctgcaccagtcaaat
acttccttcattaagctgaataataatggctttgaagatattgtcattgttatagatcct
agtgtgccagaagatgaaaaaataattgaacaaatagaggatatggtgactacagcttct
acgtacctgtttgaagccacagaaaaaagattttttttcaaaaatgtatctatattaatt
cctgagaattggaaggaaaatcctcagtacaaaaggccaaaacatgaaaaccataaacat
gctgatgttatagttgcaccacctacactcccaggtagagatgaaccatacaccaagcag
ttcacagaatgtggagagaaaggcgaatacattcacttcacccctgaccttctacttgga
aaaaaacaaaatgaatatggaccaccaggcaaactgtttgtccatgagtgggctcacctc
cggtggggagtgtttgatgagtacaatgaagatcagcctttctaccgtgctaagtcaaaa
aaaatcgaagcaacaaggtgttccgcaggtatctctggtagaaatagagtttataagtgt
caaggaggcagctgtcttagtagagcatgcagaattgattctacaacaaaactgtatgga
aaagattgtcaattctttcctgataaagtacaaacagaaaaagcatccataatgtttatg
caaagtattgattctgttgttgaattttgtaacgaaaaaacccataatcaagaagctcca
agcctacaaaacataaagtgcaattttagaagtacatgggaggtgattagcaattctgag
gattttaaaaacaccatacccatggtgacaccacctcctccacctgtcttctcattgctg
aagatcagtcaaagaattgtgtgcttagttcttgataagtctggaagcatggggggtaag
gaccgcctaaatcgaatgaatcaagcagcaaaacatttcctgctgcagactgttgaaaat
ggatcctgggtggggatggttcactttgatagtactgccactattgtaaataagctaatc
caaataaaaagcagtgatgaaagaaacacactcatggcaggattacctacatatcctctg
ggaggaacttccatctgctctggaattaaatatgcatttcaggtgattggagagctacat
tcccaactcgatggatccgaagtactgctgctgactgatggggaggataacactgcaagt
tcttgtattgatgaagtgaaacaaagtggggccattgttcattttattgctttgggaaga
gctgctgatgaagcagtaatagagatgagcaagataacaggaggaagtcatttttatgtt
tcagatgaagctcagaacaatggcctcattgatgcttttggggctcttacatcaggaaat
actgatctctcccagaagtcccttcagctcgaaagtaagggattaacactgaatagtaat
gcctggatgaacgacactgtcataattgatagtacagtgggaaaggacacgttctttctc
atcacatggaacagtctgcctcccagtatttctctctgggatcccagtggaacaataatg
gaaaatttcacagtggatgcaacttccaaaatggcctatctcagtattccaggaactgca
aaggtgggcacttgggcatacaatcttcaagccaaagcgaacccagaaacattaactatt
acagtaacttctcgagcagcaaattcttctgtgcctccaatcacagtgaatgctaaaatg
aataaggacgtaaacagtttccccagcccaatgattgtttacgcagaaattctacaagga
tatgtacctgttcttggagccaatgtgactgctttcattgaatcacagaatggacataca
gaagttttggaacttttggataatggtgcaggcgctgattctttcaagaatgatggagtc
tactccaggtattttacagcatatacagaaaatggcagatatagcttaaaagttcgggct
catggaggagcaaacactgccaggctaaaattacggcctccactgaatagagccgcgtac
ataccaggctgggtagtgaacggggaaattgaagcaaacccgccaagacctgaaattgat
gaggatactcagaccaccttggaggatttcagccgaacagcatccggaggtgcatttgtg
gtatcacaagtcccaagccttcccttgcctgaccaatacccaccaagtcaaatcacagac
cttgatgccacagttcatgaggataagattattcttacatggacagcaccaggagataat
tttgatgttggaaaagttcaacgttatatcataagaataagtgcaagtattcttgatcta
agagacagttttgatgatgctcttcaagtaaatactactgatctgtcaccaaaggaggcc
aactccaaggaaagctttgcatttaaaccagaaaatatctcagaagaaaatgcaacccac
atatttattgccattaaaagtatagataaaagcaatttgacatcaaaagtatccaacatt
gcacaagtaactttgtttatccctcaagcaaatcctgatgacattgatcctacacctact
cctactcctactcctactcctgataaaagtcataattctggagttaatatttctacgctg
gtattgtctgtgattgggtctgttgtaattgttaactttattttaagtaccaccatttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (29)   
   RefSeq(nuc) (3)   
   GenBank (13)   
   EMBL (13)   
Protein domain (4)   
   Pfam (4)   
All databases (69)   

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