KEGG   Homo sapiens (human): 22858
Entry
22858             CDS       T01001                                 
Symbol
CILK1, ECO, EJM10, ICK, LCK2, MRK, hICK
Name
(RefSeq) ciliogenesis associated kinase 1
  KO
K08828  intestinal cell (MAK-like) kinase [EC:2.7.11.22]
Organism
hsa  Homo sapiens (human)
Disease
H00972  Endocrine-cerebro-osteodysplasia syndrome
H02217  Juvenile myoclonic epilepsy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    22858 (CILK1)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    22858 (CILK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     22858 (CILK1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  RCK family [OT]
   22858 (CILK1)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  Other primary cilia associated proteins
   22858 (CILK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Haspin_kinase Anoct_dimer
Other DBs
NCBI-GeneID: 22858
NCBI-ProteinID: NP_055735
OMIM: 612325
HGNC: 21219
Ensembl: ENSG00000112144
UniProt: Q9UPZ9
Position
6:complement(53001303..53061824)
AA seq 632 aa
MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA
NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG
FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP
IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ
CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS
EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH
PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD
LDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPT
LRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNS
VGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHT
QPRSTPGLIPRPPAAQPVHGRTDWASKYASRR
NT seq 1899 nt   +upstreamnt  +downstreamnt
atgaatagatacacaacaatcaggcagctcggggatggaacctacggttccgtcctgctg
ggaagaagcattgagtctggggagctgatcgctattaaaaaaatgaaaagaaaattttat
tcctgggaggaatgcatgaaccttcgggaggttaagtctttaaagaagctcaaccatgcc
aatgtagtcaaattaaaagaagttatcagggaaaatgatcatctttattttatcttcgag
tacatgaaggaaaatctttaccagctcattaaagagagaaataagttgtttcctgagtct
gctataaggaatatcatgtatcagatattacaaggactcgcatttattcacaaacacggc
ttctttcatcgagacttaaagcctgagaacctcctctgcatgggaccagaacttgtgaaa
attgcagactttggtttggcccgagaaatacgatcaaaacctccatatacagattatgta
tctaccagatggtacagggctccagaagtactcctgaggtctaccaactacagctccccc
attgacgtctgggcggtgggctgcatcatggcagaagtttacaccctcaggccactcttc
cctggagccagtgaaattgacacaatattcaaaatttgccaagtgctggggacaccaaaa
aagactgactggcctgaaggctatcaactttcaagtgcaatgaacttccgttggccacag
tgtgtacccaataacttaaagaccttgattcccaatgctagcagtgaagcagtccagctc
ctgagagacatgcttcagtgggatcccaagaaacgaccaacagctagtcaggcacttcga
tatccttacttccaagttggacacccactaggcagcaccacacaaaaccttcaggattca
gaaaaaccacagaaaggcatcctggaaaaggcaggcccacctccttatattaagccagtc
ccacctgcccagccaccagccaagccacacacacgaatttcttcacgacagcatcaagcc
agccagccccctctgcatctcacgtacccctacaaagcagaggtctccaggacagatcac
ccaagccatctccaggaggacaagccaagcccgttgcttttcccatccctccacaacaag
catccacagtcgaaaatcacagctggcctggagcacaaaaatggtgagataaagccaaag
agtaggagaaggtggggtcttatttccaggtcaacaaaggattcagatgattgggctgac
ttggatgacttggatttcagtccatccctcagcaggattgacctgaaaaacaagaaaaga
cagagtgatgacactctctgcaggtttgagagtgttttggacctgaagccctctgagcct
gtgggcacaggaaacagtgcccccacccagacgtcatatcagcggcgagacacgcccacc
ctgagatctgcagccaagcagcactatttgaagcactctcgatacttgcctgggatcagt
ataagaaatggcatactctcgaatccaggcaaggaatttattccacctaatccatggtct
agttctggcttgtctggaaaatcttcagggacaatgtcagtaatcagcaaagtaaattca
gttggttccagctctacaagttctagtggactgactggaaactatgtcccttcctttctg
aaaaaagaaatcggttctgctatgcagagggtacacctagcacctattccagacccttcc
cctggttattcctccctgaaggccatgagacctcatcctgggcgaccattcttccacacc
cagcctagaagcactcctgggttgataccacggcctccagccgcccagccagtgcatggc
cggacagactgggcttccaagtacgcatctcggcgatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (34)   
   RefSeq(nuc) (10)   
   GenBank (12)   
   EMBL (12)   
Protein domain (5)   
   Pfam (5)   
All databases (79)   

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