KEGG   Homo sapiens (human): 2289
Entry
2289              CDS       T01001                                 
Symbol
FKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
Name
(RefSeq) FKBP prolyl isomerase 5
  KO
K09571  FK506-binding protein 4/5 [EC:5.2.1.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
Disease
H01646  Major depressive disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    2289 (FKBP5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    2289 (FKBP5)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.8  peptidylprolyl isomerase
     2289 (FKBP5)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Peptidyl prolyl isomerase
   FKBP
    2289 (FKBP5)
SSDB
Motif
Pfam: FKBP_C TPR_1 TPR_2 TPR_8 TPR_6 TPR_12 TPR_19 TPR_16 TPR_11 TPR_9 Fis1_TPR_C ANAPC3 PknG_TPR TPR_7 TPR_14 ARM_TT21_4th TPR_10 TPR_NUP160_120_M TPR_CcmH_CycH DUF3856
Other DBs
NCBI-GeneID: 2289
NCBI-ProteinID: NP_001139247
OMIM: 602623
HGNC: 3721
Ensembl: ENSG00000096060
UniProt: Q13451
Structure
Position
6:complement(35573590..35728583)
AA seq 457 aa
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
NT seq 1374 nt   +upstreamnt  +downstreamnt
atgactactgatgaaggtgccaagaacaatgaagaaagccccacagccactgttgctgag
cagggagaggatattacctccaaaaaagacaggggagtattaaagattgtcaaaagagtg
gggaatggtgaggaaacgccgatgattggagacaaagtttatgtccattacaaaggaaaa
ttgtcaaatggaaagaagtttgattccagtcatgatagaaatgaaccatttgtctttagt
cttggcaaaggccaagtcatcaaggcatgggacattggggtggctaccatgaagaaagga
gagatatgccatttactgtgcaaaccagaatatgcatatggctcggctggcagtctccct
aaaattccctcgaatgcaactctcttttttgagattgagctccttgatttcaaaggagag
gatttatttgaagatggaggcattatccggagaaccaaacggaaaggagagggatattca
aatccaaacgaaggagcaacagtagaaatccacctggaaggccgctgtggtggaaggatg
tttgactgcagagatgtggcattcactgtgggcgaaggagaagaccacgacattccaatt
ggaattgacaaagctctggagaaaatgcagcgggaagaacaatgtattttatatcttgga
ccaagatatggttttggagaggcagggaagcctaaatttggcattgaacctaatgctgag
cttatatatgaagttacacttaagagcttcgaaaaggccaaagaatcctgggagatggat
accaaagaaaaattggagcaggctgccattgtcaaagagaagggaaccgtatacttcaag
ggaggcaaatacatgcaggcggtgattcagtatgggaagatagtgtcctggttagagatg
gaatatggtttatcagaaaaggaatcgaaagcttctgaatcatttctccttgctgccttt
ctgaacctggccatgtgctacctgaagcttagagaatacaccaaagctgttgaatgctgt
gacaaggcccttggactggacagtgccaatgagaaaggcttgtataggaggggtgaagcc
cagctgctcatgaacgagtttgagtcagccaagggtgactttgagaaagtgctggaagta
aacccccagaataaggctgcaagactgcagatctccatgtgccagaaaaaggccaaggag
cacaacgagcgggaccgcaggatatacgccaacatgttcaagaagtttgcagagcaggat
gccaaggaagaggccaataaagcaatgggcaagaagacttcagaaggggtcactaatgaa
aaaggaacagacagtcaagcaatggaagaagagaaacctgagggccacgtatga

  All links  
Disease (2)   
   OMIM (2)   
Gene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (34)   
   RefSeq(nuc) (4)   
   GenBank (15)   
   EMBL (15)   
3D Structure (133)   
   PDB (133)   
Protein domain (20)   
   Pfam (20)   
All databases (203)   

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