KEGG   Homo sapiens (human): 2289
Entry
2289              CDS       T01001                                 
Symbol
FKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
Name
(RefSeq) FKBP prolyl isomerase 5
  KO
K09571  FK506-binding protein 4/5 [EC:5.2.1.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
Disease
H01646  Major depressive disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    2289 (FKBP5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    2289 (FKBP5)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.8  peptidylprolyl isomerase
     2289 (FKBP5)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Peptidyl prolyl isomerase
   FKBP
    2289 (FKBP5)
SSDB
Motif
Pfam: FKBP_C TPR_1 TPR_2 TPR_8 TPR_6 TPR_19 TPR_7 TPR_12 TPR_9 TPR_11 Fis1_TPR_C ANAPC3 PknG_TPR NatA_aux_su
Other DBs
NCBI-GeneID: 2289
NCBI-ProteinID: NP_001139247
OMIM: 602623
HGNC: 3721
Ensembl: ENSG00000096060
Pharos: Q13451(Tchem)
UniProt: Q13451
Structure
Position
6:complement(35573590..35728583)
AA seq 457 aa
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
NT seq 1374 nt   +upstreamnt  +downstreamnt
atgactactgatgaaggtgccaagaacaatgaagaaagccccacagccactgttgctgag
cagggagaggatattacctccaaaaaagacaggggagtattaaagattgtcaaaagagtg
gggaatggtgaggaaacgccgatgattggagacaaagtttatgtccattacaaaggaaaa
ttgtcaaatggaaagaagtttgattccagtcatgatagaaatgaaccatttgtctttagt
cttggcaaaggccaagtcatcaaggcatgggacattggggtggctaccatgaagaaagga
gagatatgccatttactgtgcaaaccagaatatgcatatggctcggctggcagtctccct
aaaattccctcgaatgcaactctcttttttgagattgagctccttgatttcaaaggagag
gatttatttgaagatggaggcattatccggagaaccaaacggaaaggagagggatattca
aatccaaacgaaggagcaacagtagaaatccacctggaaggccgctgtggtggaaggatg
tttgactgcagagatgtggcattcactgtgggcgaaggagaagaccacgacattccaatt
ggaattgacaaagctctggagaaaatgcagcgggaagaacaatgtattttatatcttgga
ccaagatatggttttggagaggcagggaagcctaaatttggcattgaacctaatgctgag
cttatatatgaagttacacttaagagcttcgaaaaggccaaagaatcctgggagatggat
accaaagaaaaattggagcaggctgccattgtcaaagagaagggaaccgtatacttcaag
ggaggcaaatacatgcaggcggtgattcagtatgggaagatagtgtcctggttagagatg
gaatatggtttatcagaaaaggaatcgaaagcttctgaatcatttctccttgctgccttt
ctgaacctggccatgtgctacctgaagcttagagaatacaccaaagctgttgaatgctgt
gacaaggcccttggactggacagtgccaatgagaaaggcttgtataggaggggtgaagcc
cagctgctcatgaacgagtttgagtcagccaagggtgactttgagaaagtgctggaagta
aacccccagaataaggctgcaagactgcagatctccatgtgccagaaaaaggccaaggag
cacaacgagcgggaccgcaggatatacgccaacatgttcaagaagtttgcagagcaggat
gccaaggaagaggccaataaagcaatgggcaagaagacttcagaaggggtcactaatgaa
aaaggaacagacagtcaagcaatggaagaagagaaacctgagggccacgtatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (34)   
   RefSeq(nuc) (4)   
   GenBank (15)   
   EMBL (15)   
3D Structure (59)   
   PDB (59)   
Protein domain (14)   
   Pfam (14)   
All databases (133)   

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