KEGG   Homo sapiens (human): 2289Help
Entry
2289              CDS       T01001                                 

Gene name
FKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
Definition
(RefSeq) FK506 binding protein 5
  KO
K09571  FK506-binding protein 4/5 [EC:5.2.1.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
Disease
H01646  Major depressive disorder (MDD)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Endocrine system
   04915 Estrogen signaling pathway
    2289 (FKBP5)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.8  peptidylprolyl isomerase
     2289 (FKBP5)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Peptidyl prolyl isomerase
   FKBP
    2289 (FKBP5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: FKBP_C TPR_1 TPR_2 TPR_8 TPR_6 TPR_19 TPR_7 TPR_12 Fis1_TPR_C TPR_11 TPR_9 ANAPC3 PknG_TPR NARP1 TPR_14 TPR_10
Motif
Other DBs
NCBI-GeneID: 2289
NCBI-ProteinID: NP_001139247
OMIM: 602623
HGNC: 3721
Ensembl: ENSG00000096060
Vega: OTTHUMG00000014576
Pharos: Q13451(Tchem)
UniProt: Q13451
Structure
PDB: 

Position
6p21.31
AA seq 457 aa AA seqDB search
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
NT seq 1374 nt NT seq  +upstreamnt  +downstreamnt
atgactactgatgaaggtgccaagaacaatgaagaaagccccacagccactgttgctgag
cagggagaggatattacctccaaaaaagacaggggagtattaaagattgtcaaaagagtg
gggaatggtgaggaaacgccgatgattggagacaaagtttatgtccattacaaaggaaaa
ttgtcaaatggaaagaagtttgattccagtcatgatagaaatgaaccatttgtctttagt
cttggcaaaggccaagtcatcaaggcatgggacattggggtggctaccatgaagaaagga
gagatatgccatttactgtgcaaaccagaatatgcatatggctcggctggcagtctccct
aaaattccctcgaatgcaactctcttttttgagattgagctccttgatttcaaaggagag
gatttatttgaagatggaggcattatccggagaaccaaacggaaaggagagggatattca
aatccaaacgaaggagcaacagtagaaatccacctggaaggccgctgtggtggaaggatg
tttgactgcagagatgtggcattcactgtgggcgaaggagaagaccacgacattccaatt
ggaattgacaaagctctggagaaaatgcagcgggaagaacaatgtattttatatcttgga
ccaagatatggttttggagaggcagggaagcctaaatttggcattgaacctaatgctgag
cttatatatgaagttacacttaagagcttcgaaaaggccaaagaatcctgggagatggat
accaaagaaaaattggagcaggctgccattgtcaaagagaagggaaccgtatacttcaag
ggaggcaaatacatgcaggcggtgattcagtatgggaagatagtgtcctggttagagatg
gaatatggtttatcagaaaaggaatcgaaagcttctgaatcatttctccttgctgccttt
ctgaacctggccatgtgctacctgaagcttagagaatacaccaaagctgttgaatgctgt
gacaaggcccttggactggacagtgccaatgagaaaggcttgtataggaggggtgaagcc
cagctgctcatgaacgagtttgagtcagccaagggtgactttgagaaagtgctggaagta
aacccccagaataaggctgcaagactgcagatctccatgtgccagaaaaaggccaaggag
cacaacgagcgggaccgcaggatatacgccaacatgttcaagaagtttgcagagcaggat
gccaaggaagaggccaataaagcaatgggcaagaagacttcagaaggggtcactaatgaa
aaaggaacagacagtcaagcaatggaagaagagaaacctgagggccacgtatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (34)   
   RefSeq(nuc) (4)   
   GenBank (15)   
   EMBL (15)   
Protein domain (16)   
   Pfam (16)   
All databases (77)   

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